Microglia undergo disease-associated transcriptional activation and CX3C motif chemokine receptor 1 expression regulates neurogenesis in the aged brain.
Fritze J, Muralidharan C, Stamp E, Ahlenius H.

Microglial phagocytosis of single dying oligodendrocytes is mediated by CX3CR1 but not MERTK.
Olveda GE, Barasa MN, Hill RA., Free PMC Article

Mild Hypoxia Accelerates Cerebral Cavernous Malformation Disease Through CX3CR1-CX3CL1 Signaling.
Frias-Anaya E, Gallego-Gutierrez H, Gongol B, Weinsheimer S, Lai CC, Orecchioni M, Sriram A, Bui CM, Nelsen B, Hale P, Pham A, Shenkar R, DeBiasse D, Lightle R, Girard R, Li Y, Srinath A, Daneman R, Nudleman E, Sun H, Guma M, Dubrac A, Mesarwi OA, Ley K, Kim H, Awad IA, Ginsberg MH, Lopez-Ramirez MA.,

CX3CR1 deficiency promotes resolution of hepatic ischemia-reperfusion injury by regulating homeostatic function of liver infiltrating macrophages.
Zhang H, You G, Yang Q, Jin G, Lv G, Fan L, Chen Y, Li H, Yi S, Li H, Guo N, Liu W, Yang Y.

Pneumococcal Meningitis Induces Hearing Loss and Cochlear Ossification Modulated by Chemokine Receptors CX3CR1 and CCR2.
Hirose K, Li SZ, Gill R, Hartsock J.,

Fractalkine isoforms differentially regulate microglia-mediated inflammation and enhance visual function in the diabetic retina.
Rodriguez D, Church KA, Pietramale AN, Cardona SM, Vanegas D, Rorex C, Leary MC, Muzzio IA, Nash KR, Cardona AE., Free PMC Article

FKN secreted by kidney epithelial cells regulates macrophage activation in lupus nephritis via the Hippo signaling pathway.
Zuo Y, Pan X, Wang X, You Y.

CX3CR1 mediates motor dysfunction in mice through 5-HTR2a.
Pei J, Zou Y, Wan C, Liu S, Hu B, Li Z, Tang Z.

Non-classical monocytes promote neurovascular repair in cerebral small vessel disease associated with microinfarctions via CX3CR1.
Lecordier S, Menet R, Allain AS, ElAli A., Free PMC Article

CX3CL1 represses autophagy via CX3CR1/ CaMKIIδ/HDAC4/Rubicon axis and exacerbates chronic intermittent hypoxia induced Kupffer cell apoptosis.
Li Y, Chen Y, Xiao X, Deng S, Kuang J, Wang Y.

Chronic hyperpalatable diet induces impairment of hippocampal-dependent memories and alters glutamatergic and fractalkine axis signaling.
Ribeiro R, Silva EG, Moreira FC, Gomes GF, Cussat GR, Silva BSR, da Silva MCM, de Barros Fernandes H, de Sena Oliveira C, de Oliveira Guarnieri L, Lopes V, Ferreira CN, de Faria AMC, Maioli TU, Ribeiro FM, de Miranda AS, Moraes GSP, de Oliveira ACP, Vieira LB., Free PMC Article

CX3CR1 regulates the development of renal interstitial fibrosis through macrophage polarization.
Xu L, Zhu Y, Cai H, Liu S, Cao Q, Zhuang Q., Free PMC Article

Graded expression of the chemokine receptor CX3CR1 marks differentiation states of human and murine T cells and enables cross-species interpretation.
Zwijnenburg AJ, Pokharel J, Varnaitė R, Zheng W, Hoffer E, Shryki I, Comet NR, Ehrström M, Gredmark-Russ S, Eidsmo L, Gerlach C.

Microglial LRRK2-mediated NFATc1 attenuates α-synuclein immunotoxicity in association with CX3CR1-induced migration and the lysosome-initiated degradation.
Feng L, Lo H, Hong Z, Zheng J, Yan Y, Ye Z, Chen X, Pan X.

Influence of CX3CR1 Deletion on Cochlear Hair Cell Survival and Macrophage Expression in Chronic Suppurative Otitis Media.
Schiel V, Xia A, Santa Maria PL., Free PMC Article

Cx3cr1 controls kidney resident macrophage heterogeneity.
Yashchenko A, Bland SJ, Song CJ, Ahmed UKB, Sharp R, Darby IG, Cordova AM, Smith ME, Lever JM, Li Z, Aloria EJ, Khan S, Maryam B, Liu S, Crowley MR, Jones KL, Zenewicz LA, George JF, Mrug M, Crossman DK, Hopp K, Stavrakis S, Humphrey MB, Ginhoux F, Zimmerman KA., Free PMC Article

CX3CR1(hi) macrophages sustain metabolic adaptation by relieving adipose-derived stem cell senescence in visceral adipose tissue.
Zhou Z, Zhang H, Tao Y, Jie H, Zhao J, Zang J, Li H, Wang Y, Wang T, Zhao H, Li Y, Guo C, Zhu F, Mao H, Zhang L, Liu F, Wang Q.

CX(3)CR1 modulates SLE-associated glomerulonephritis and cardiovascular disease in MRL/lpr mice.
Cabana-Puig X, Lu R, Geng S, Michaelis JS, Oakes V, Armstrong C, Testerman JC, Liao X, Alajoleen R, Appiah M, Zhang Y, Reilly CM, Li L, Luo XM., Free PMC Article

CX3CR1 deficiency exacerbates immune-mediated hepatitis by increasing NF-κB-mediated cytokine production in macrophage and T cell.
Ren M, Zhang J, Dai S, Wang C, Chen Z, Zhang S, Xu J, Qin X, Liu F., Free PMC Article

CX3CR1 deficiency leads to impairment of immune surveillance in the epididymis.
Barrachina F, Ottino K, Tu LJ, Soberman RJ, Brown D, Breton S, Battistone MA., Free PMC Article

CX3CL1/CX3CR1 interaction protects against lipotoxicity-induced nonalcoholic steatohepatitis by regulating macrophage migration and M1/M2 status.
Ni Y, Zhuge F, Ni L, Nagata N, Yamashita T, Mukaida N, Kaneko S, Ota T, Nagashimada M.

Chronic social instability stress down-regulates IL-10 and up-regulates CX3CR1 in tumor-bearing and non-tumor-bearing female mice.
Díez-Solinska A, Lebeña A, Garmendia L, Labaka A, Azkona G, Perez-Tejada J, Vegas O.

Multiple Mild Stimulations Reduce Membrane Distribution of CX3CR1 Promoted by Annexin a1 in Microglia to Attenuate Excessive Dendritic Spine Pruning and Cognitive Deficits Caused by a Transient Ischemic Attack in Mice.
Zheng L, Wang Y, Shao B, Zhou H, Li X, Zhang C, Sun N, Shi J., Free PMC Article

CX3CR1 deficiency aggravates amyloid driven neuronal pathology and cognitive decline in Alzheimer's disease.
Puntambekar SS, Moutinho M, Lin PB, Jadhav V, Tumbleson-Brink D, Balaji A, Benito MA, Xu G, Oblak A, Lasagna-Reeves CA, Landreth GE, Lamb BT., Free PMC Article

CX3CR1-Expressing Myeloid Cells Regulate Host-Helminth Interaction and Lung Inflammation.
Kim SY, Barnes MA, Sureshchandra S, Menicucci AR, Patel JJ, Messaoudi I, Nair MG., Free PMC Article