| A CTCF-binding site in the Mdm1-Il22-Ifng locus shapes cytokine expression profiles and plays a critical role in early Th1 cell fate specification. | A CTCF-binding site in the Mdm1-Il22-Ifng locus shapes cytokine expression profiles and plays a critical role in early Th1 cell fate specification.
Liu C, Nagashima H, Fernando N, Bass V, Gopalakrishnan J, Signorella S, Montgomery W, Lim AI, Harrison O, Reich L, Yao C, Sun HW, Brooks SR, Jiang K, Nagarajan V, Zhao Y, Jung S, Phillips R, Mikami Y, Lareau CA, Kanno Y, Jankovic D, Aryee MJ, Pękowska A, Belkaid Y, O'Shea J, Shih HY., | 08/5/2024 |
| CTCF mutation at R567 causes developmental disorders via 3D genome rearrangement and abnormal neurodevelopment. | CTCF mutation at R567 causes developmental disorders via 3D genome rearrangement and abnormal neurodevelopment.
Zhang J, Hu G, Lu Y, Ren H, Huang Y, Wen Y, Ji B, Wang D, Wang H, Liu H, Ma N, Zhang L, Pan G, Qu Y, Wang H, Zhang W, Miao Z, Yao H., Free PMC Article | 07/22/2024 |
| Transcriptional regulation of FACT involves Coordination of chromatin accessibility and CTCF binding. | Transcriptional regulation of FACT involves Coordination of chromatin accessibility and CTCF binding.
Wang P, Fan N, Yang W, Cao P, Liu G, Zhao Q, Guo P, Li X, Lin X, Jiang N, Nashun B., Free PMC Article | 07/1/2024 |
| Systematic assessment of ISWI subunits shows that NURF creates local accessibility for CTCF. | Systematic assessment of ISWI subunits shows that NURF creates local accessibility for CTCF.
Iurlaro M, Masoni F, Flyamer IM, Wirbelauer C, Iskar M, Burger L, Giorgetti L, Schübeler D., Free PMC Article | 06/26/2024 |
| ADNP modulates SINE B2-derived CTCF-binding sites during blastocyst formation in mice. | ADNP modulates SINE B2-derived CTCF-binding sites during blastocyst formation in mice.
Wang W, Gao R, Yang D, Ma M, Zang R, Wang X, Chen C, Kou X, Zhao Y, Chen J, Liu X, Lu J, Xu B, Liu J, Huang Y, Chen C, Wang H, Gao S, Zhang Y, Gao Y., Free PMC Article | 04/4/2024 |
| CCCTC-binding factor: the specific transcription factor of beta-galactoside alpha-2,6-sialyltransferase 1 that upregulates the sialylation of anti-citrullinated protein antibodies in rheumatoid arthritis. | CCCTC-binding factor: the specific transcription factor of β-galactoside α-2,6-sialyltransferase 1 that upregulates the sialylation of anti-citrullinated protein antibodies in rheumatoid arthritis.
Zhao H, Wang H, Qin Y, Ling S, Zhai H, Jin J, Fang L, Cao Z, Jin S, Yang X, Wang J. | 03/5/2024 |
| Outward-oriented sites within clustered CTCF boundaries are key for intra-TAD chromatin interactions and gene regulation. | Outward-oriented sites within clustered CTCF boundaries are key for intra-TAD chromatin interactions and gene regulation.
Ge X, Huang H, Han K, Xu W, Wang Z, Wu Q., Free PMC Article | 01/8/2024 |
| CTCF coordinates cell fate specification via orchestrating regulatory hubs with pioneer transcription factors. | CTCF coordinates cell fate specification via orchestrating regulatory hubs with pioneer transcription factors.
Liu Y, Wan X, Li H, Chen Y, Hu X, Chen H, Zhu D, Li C, Zhang Y. | 11/29/2023 |
| Sequential and directional insulation by conserved CTCF sites underlies the Hox timer in stembryos. | Sequential and directional insulation by conserved CTCF sites underlies the Hox timer in stembryos.
Rekaik H, Lopez-Delisle L, Hintermann A, Mascrez B, Bochaton C, Mayran A, Duboule D., Free PMC Article | 10/20/2023 |
| SATB1 regulates 3D genome architecture in T cells by constraining chromatin interactions surrounding CTCF-binding sites. | SATB1 regulates 3D genome architecture in T cells by constraining chromatin interactions surrounding CTCF-binding sites.
Wang B, Ji L, Bian Q. | 10/6/2023 |
| Chromatin architectural factor CTCF is essential for progesterone-dependent uterine maturation. | Chromatin architectural factor CTCF is essential for progesterone-dependent uterine maturation.
Hewitt SC, Gruzdev A, Willson CJ, Wu SP, Lydon JP, Galjart N, DeMayo FJ., Free PMC Article | 09/8/2023 |
| CCCTC-Binding Factor Mediates the Transcription of Insulin-Like Growth Factor Binding Protein 5 Through EZH2 in Ulcerative Colitis. | CCCTC-Binding Factor Mediates the Transcription of Insulin-Like Growth Factor Binding Protein 5 Through EZH2 in Ulcerative Colitis.
Gu D, Cao T, Yi S, Liu Y, Fan C. | 03/16/2023 |
| Enhancer-promoter interactions and transcription are largely maintained upon acute loss of CTCF, cohesin, WAPL or YY1. | Enhancer-promoter interactions and transcription are largely maintained upon acute loss of CTCF, cohesin, WAPL or YY1.
Hsieh TS, Cattoglio C, Slobodyanyuk E, Hansen AS, Darzacq X, Tjian R., Free PMC Article | 12/17/2022 |
| Recruitment of CTCF to an Fto enhancer is responsible for transgenerational inheritance of BPA-induced obesity. | Recruitment of CTCF to an Fto enhancer is responsible for transgenerational inheritance of BPA-induced obesity.
Jung YH, Wang HV, Ruiz D, Bixler BJ, Linsenbaum H, Xiang JF, Forestier S, Shafik AM, Jin P, Corces VG., Free PMC Article | 12/17/2022 |
| Establishment of 3D chromatin structure after fertilization and the metabolic switch at the morula-to-blastocyst transition require CTCF. | Establishment of 3D chromatin structure after fertilization and the metabolic switch at the morula-to-blastocyst transition require CTCF.
Andreu MJ, Alvarez-Franco A, Portela M, Gimenez-Llorente D, Cuadrado A, Badia-Careaga C, Tiana M, Losada A, Manzanares M. | 10/29/2022 |
| Cooperation of ATF4 and CTCF promotes adipogenesis through transcriptional regulation. | Cooperation of ATF4 and CTCF promotes adipogenesis through transcriptional regulation.
Chen Y, He R, Han Z, Wu Y, Wang Q, Zhu X, Huang Z, Ye J, Tang Y, Huang H, Chen J, Shan H, Xiao F. | 10/8/2022 |
| CTCF and cohesin promote focal detachment of DNA from the nuclear lamina. | CTCF and cohesin promote focal detachment of DNA from the nuclear lamina.
van Schaik T, Liu NQ, Manzo SG, Peric-Hupkes D, de Wit E, van Steensel B., Free PMC Article | 09/17/2022 |
| Alcohol induced increases in sperm Histone H3 lysine 4 trimethylation correlate with increased placental CTCF occupancy and altered developmental programming. | Alcohol induced increases in sperm Histone H3 lysine 4 trimethylation correlate with increased placental CTCF occupancy and altered developmental programming.
Bedi YS, Wang H, Thomas KN, Basel A, Prunier J, Robert C, Golding MC., Free PMC Article | 06/11/2022 |
| CCCTC-binding factor is an upstream regulator of the pluripotency factor Oct4 and functions in active transcription of linc1253 and linc1356 genes in pluripotent cells. | CCCTC-binding factor is an upstream regulator of the pluripotency factor Oct4 and functions in active transcription of linc1253 and linc1356 genes in pluripotent cells.
Wang F, Ci B, Wang Y. | 04/30/2022 |
| CTCF functions as an insulator for somatic genes and a chromatin remodeler for pluripotency genes during reprogramming. | CTCF functions as an insulator for somatic genes and a chromatin remodeler for pluripotency genes during reprogramming.
Song Y, Liang Z, Zhang J, Hu G, Wang J, Li Y, Guo R, Dong X, Babarinde IA, Ping W, Sheng YL, Li H, Chen Z, Gao M, Chen Y, Shan G, Zhang MQ, Hutchins AP, Fu XD, Yao H. | 04/23/2022 |
| CTCF in parvalbumin-expressing neurons regulates motor, anxiety and social behavior and neuronal identity. | CTCF in parvalbumin-expressing neurons regulates motor, anxiety and social behavior and neuronal identity.
Davis L, Rayi PR, Getselter D, Kaphzan H, Elliott E., Free PMC Article | 04/23/2022 |
| The number of the CTCF binding sites of the H19/IGF2:IG-DMR correlates with DNA methylation and expression imprinting in a humanized mouse model. | The number of the CTCF binding sites of the H19/IGF2:IG-DMR correlates with DNA methylation and expression imprinting in a humanized mouse model.
Freschi A, Del Prete R, Pignata L, Cecere F, Manfrevola F, Mattia M, Cobellis G, Sparago A, Bartolomei MS, Riccio A, Cerrato F., Free PMC Article | 04/16/2022 |
| Dissecting CTCF site function in a tense HoxD locus. | Dissecting CTCF site function in a tense HoxD locus.
Bruneau BG., Free PMC Article | 04/9/2022 |
| Liver-Specific Deletion of Mouse CTCF Leads to Hepatic Steatosis via Augmented PPARgamma Signaling. | Liver-Specific Deletion of Mouse CTCF Leads to Hepatic Steatosis via Augmented PPARγ Signaling.
Choi Y, Song MJ, Jung WJ, Jeong H, Park S, Yang B, Lee EC, Joo JS, Choi D, Koo SH, Kim EK, Nam KT, Kim HP., Free PMC Article | 04/2/2022 |
| CRISPR and biochemical screens identify MAZ as a cofactor in CTCF-mediated insulation at Hox clusters. | CRISPR and biochemical screens identify MAZ as a cofactor in CTCF-mediated insulation at Hox clusters.
Ortabozkoyun H, Huang PY, Cho H, Narendra V, LeRoy G, Gonzalez-Buendia E, Skok JA, Tsirigos A, Mazzoni EO, Reinberg D., Free PMC Article | 02/26/2022 |