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    Csf2 colony stimulating factor 2 (granulocyte-macrophage) [ Mus musculus (house mouse) ]

    Gene ID: 12981, updated on 10-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    A GITRL-mTORC1-GM-CSF Positive Loop Promotes Pathogenic Th17 Response in Primary Sjogren Syndrome.

    A GITRL-mTORC1-GM-CSF Positive Loop Promotes Pathogenic Th17 Response in Primary Sjögren Syndrome.
    Gan Y, Zhou H, Guo Y, Huang B, Liu H, Wang Z, Li Z, Zhao X, Zhu H, Han Q, Ye H, He J, Wang Q, Li Z, Sun X.

    08/31/2024
    CD73 induces GM-CSF/MDSC-mediated suppression of T cells to accelerate pancreatic cancer pathogenesis.

    CD73 induces GM-CSF/MDSC-mediated suppression of T cells to accelerate pancreatic cancer pathogenesis.
    King RJ, Shukla SK, He C, Vernucci E, Thakur R, Attri KS, Dasgupta A, Chaika NV, Mulder SE, Abrego J, Murthy D, Gunda V, Pacheco CG, Grandgenett PM, Lazenby AJ, Hollingsworth MA, Yu F, Mehla K, Singh PK., Free PMC Article

    08/27/2024
    Granulocyte macrophage colony stimulating factor exerts dominant effects over macrophage colony stimulating factor during macrophage differentiation in vitro to induce an inflammatory phenotype.

    Granulocyte macrophage colony stimulating factor exerts dominant effects over macrophage colony stimulating factor during macrophage differentiation in vitro to induce an inflammatory phenotype.
    Petrina M, Alothaimeen T, Bouzeineddine NZ, Trus E, Banete A, Gee K, Basta S.

    02/15/2024
    CSF2 upregulates CXCL3 expression in adipocytes to promote metastasis of breast cancer via the FAK signaling pathway.

    CSF2 upregulates CXCL3 expression in adipocytes to promote metastasis of breast cancer via the FAK signaling pathway.
    He X, Wang L, Li H, Liu Y, Tong C, Xie C, Yan X, Luo D, Xiong X., Free PMC Article

    11/30/2023
    The GM-CSF/CCL17 pathway in obesity-associated osteoarthritic pain and disease in mice.

    The GM-CSF/CCL17 pathway in obesity-associated osteoarthritic pain and disease in mice.
    Shin H, Prasad V, Lupancu T, Malik S, Achuthan A, Biondo M, Kingwell BA, Thiem M, Gottschalk M, Weighardt H, Förster I, de Steiger R, Hamilton JA, Lee KM.

    09/19/2023
    Lethal eosinophilic crystalline pneumonia in mice expressing a stabilized Csf2 mRNA.

    Lethal eosinophilic crystalline pneumonia in mice expressing a stabilized Csf2 mRNA.
    Arao Y, Stumpo DJ, Hoenerhoff MJ, Tighe RM, Yu YR, Sutton D, Kashyap A, Beerman I, Blackshear PJ., Free PMC Article

    07/24/2023
    GM-CSF Promotes the Survival of Peripheral-Derived Myeloid Cells in the Central Nervous System for Pain-Induced Relapse of Neuroinflammation.

    GM-CSF Promotes the Survival of Peripheral-Derived Myeloid Cells in the Central Nervous System for Pain-Induced Relapse of Neuroinflammation.
    Matsuyama S, Yamamoto R, Murakami K, Takahashi N, Nishi R, Ishii A, Nio-Kobayashi J, Abe N, Tanaka K, Jiang JJ, Kawamoto T, Iwanaga T, Shinohara Y, Yamasaki T, Ohki I, Hojyo S, Hasebe R, Kubota SI, Hirata N, Kamimura D, Hashimoto S, Tanaka Y, Murakami M.

    06/26/2023
    Roles of CSF2 as a modulator of inflammation during retinal degeneration.

    Roles of CSF2 as a modulator of inflammation during retinal degeneration.
    Saita K, Moriuchi Y, Iwagawa T, Aihara M, Takai Y, Uchida K, Watanabe S.

    10/1/2022
    Blocking DCIR mitigates colitis and prevents colorectal tumors by enhancing the GM-CSF-STAT5 pathway.

    Blocking DCIR mitigates colitis and prevents colorectal tumors by enhancing the GM-CSF-STAT5 pathway.
    Sun H, Tang C, Chung SH, Ye XQ, Makusheva Y, Han W, Kubo M, Shichino S, Ueha S, Matsushima K, Ikeo K, Asano M, Iwakura Y.

    08/13/2022
    IFN-gamma-independent control of M. tuberculosis requires CD4 T cell-derived GM-CSF and activation of HIF-1alpha.

    IFN-γ-independent control of M. tuberculosis requires CD4 T cell-derived GM-CSF and activation of HIF-1α.
    Van Dis E, Fox DM, Morrison HM, Fines DM, Babirye JP, McCann LH, Rawal S, Cox JS, Stanley SA., Free PMC Article

    08/13/2022
    GM-CSF derived from the inflammatory microenvironment potentially enhanced PD-L1 expression on tumor-associated macrophages in human breast cancer.

    GM-CSF derived from the inflammatory microenvironment potentially enhanced PD-L1 expression on tumor-associated macrophages in human breast cancer.
    Yonemitsu K, Pan C, Fujiwara Y, Miyasato Y, Shiota T, Yano H, Hosaka S, Tamada K, Yamamoto Y, Komohara Y., Free PMC Article

    07/23/2022
    CSF2-dependent monocyte education in the pathogenesis of ANCA-induced glomerulonephritis.

    CSF2-dependent monocyte education in the pathogenesis of ANCA-induced glomerulonephritis.
    Rousselle A, Sonnemann J, Amann K, Mildner A, Lodka D, Kling L, Bieringer M, Schneider U, Leutz A, Enghard P, Kettritz R, Schreiber A., Free PMC Article

    07/16/2022
    Pathogenic Tconvs promote inflammatory macrophage polarization through GM-CSF and exacerbate abdominal aortic aneurysm formation.

    Pathogenic Tconvs promote inflammatory macrophage polarization through GM-CSF and exacerbate abdominal aortic aneurysm formation.
    Li D, Li J, Liu H, Zhai L, Hu W, Xia N, Tang T, Jiao J, Lv B, Nie S, Hu D, Liao Y, Yang X, Shi GP, Cheng X., Free PMC Article

    03/5/2022
    Group 2 innate lymphoid cells in bone marrow regulate osteoclastogenesis in a reciprocal manner via RANKL, GM-CSF and IL-13.

    Group 2 innate lymphoid cells in bone marrow regulate osteoclastogenesis in a reciprocal manner via RANKL, GM-CSF and IL-13.
    Momiuchi Y, Motomura Y, Suga E, Mizuno H, Kikuta J, Morimoto A, Mochizuki M, Otaki N, Ishii M, Moro K.

    02/19/2022
    Gas6/TAM Signalling Negatively Regulates Inflammatory Induction of GM-CSF in Mouse Brain Microglia.

    Gas6/TAM Signalling Negatively Regulates Inflammatory Induction of GM-CSF in Mouse Brain Microglia.
    Gilchrist SE, Pennelli GM, Hafizi S., Free PMC Article

    01/22/2022
    GM-CSF Nitration Is a New Driver of Myeloid Suppressor Cell Activity in Tumors.

    GM-CSF Nitration Is a New Driver of Myeloid Suppressor Cell Activity in Tumors.
    Calì B, Agnellini AHR, Cioccarelli C, Sanchez-Rodriguez R, Predonzani A, Toffolo GI, Viola A, Bronte V, Arrigoni G, Zonta F, Albertoni L, Mescoli C, Marigo I, Molon B., Free PMC Article

    12/25/2021
    IL-23p19 and CD5 antigen-like form a possible novel heterodimeric cytokine and contribute to experimental autoimmune encephalomyelitis development.

    IL-23p19 and CD5 antigen-like form a possible novel heterodimeric cytokine and contribute to experimental autoimmune encephalomyelitis development.
    Hasegawa H, Mizoguchi I, Orii N, Inoue S, Katahira Y, Yoneto T, Xu M, Miyazaki T, Yoshimoto T., Free PMC Article

    12/11/2021
    Alveolar macrophages rely on GM-CSF from alveolar epithelial type 2 cells before and after birth.

    Alveolar macrophages rely on GM-CSF from alveolar epithelial type 2 cells before and after birth.
    Gschwend J, Sherman SPM, Ridder F, Feng X, Liang HE, Locksley RM, Becher B, Schneider C., Free PMC Article

    12/4/2021
    Cytokine regulation of apoptosis-induced apoptosis and apoptosis-induced cell proliferation in vascular smooth muscle cells.

    Cytokine regulation of apoptosis-induced apoptosis and apoptosis-induced cell proliferation in vascular smooth muscle cells.
    Aravani D, Foote K, Figg N, Finigan A, Uryga A, Clarke M, Bennett M., Free PMC Article

    07/31/2021
    The effects and mechanisms of GM-CSF on endometrial regeneration.

    The effects and mechanisms of GM-CSF on endometrial regeneration.
    Liu J, Ying Y, Wang S, Li J, Xu J, Lv P, Chen J, Zhou C, Liu Y, Wu Y, Huang Y, Chen Y, Chen L, Tu S, Zhao W, Yang M, Hu Y, Zhang R, Zhang D.

    05/22/2021
    GM-CSF Dependent Differential Control of Mycobacterium tuberculosis Infection in Human and Mouse Macrophages: Is Macrophage Source of GM-CSF Critical to Tuberculosis Immunity?

    GM-CSF Dependent Differential Control of Mycobacterium tuberculosis Infection in Human and Mouse Macrophages: Is Macrophage Source of GM-CSF Critical to Tuberculosis Immunity?
    Mishra A, Singh VK, Actor JK, Hunter RL, Jagannath C, Subbian S, Khan A., Free PMC Article

    04/17/2021
    MYC-induced human acute myeloid leukemia requires a continuing IL-3/GM-CSF costimulus.

    MYC-induced human acute myeloid leukemia requires a continuing IL-3/GM-CSF costimulus.
    Bulaeva E, Pellacani D, Nakamichi N, Hammond CA, Beer PA, Lorzadeh A, Moksa M, Carles A, Bilenky M, Lefort S, Shu J, Wilhelm BT, Weng AP, Hirst M, Eaves CJ.

    04/13/2021
    Constitutive Expression of CCL22 Is Mediated by T Cell-Derived GM-CSF.

    Constitutive Expression of CCL22 Is Mediated by T Cell-Derived GM-CSF.
    Piseddu I, Röhrle N, Knott MML, Moder S, Eiber S, Schnell K, Vetter V, Meyer B, Layritz P, Kühnemuth B, Wiedemann GM, Gruen J, Perleberg C, Rapp M, Endres S, Anz D.

    04/3/2021
    Microglial Homeostasis Requires Balanced CSF-1/CSF-2 Receptor Signaling.

    Microglial Homeostasis Requires Balanced CSF-1/CSF-2 Receptor Signaling.
    Chitu V, Biundo F, Shlager GGL, Park ES, Wang P, Gulinello ME, Gokhan Ş, Ketchum HC, Saha K, DeTure MA, Dickson DW, Wszolek ZK, Zheng D, Croxford AL, Becher B, Sun D, Mehler MF, Stanley ER., Free PMC Article

    03/27/2021
    Toll-like receptor 4 regulates spontaneous intestinal tumorigenesis by up-regulating IL-6 and GM-CSF.

    Toll-like receptor 4 regulates spontaneous intestinal tumorigenesis by up-regulating IL-6 and GM-CSF.
    Shi YJ, Zhao QQ, Liu XS, Dong SH, E JF, Li X, Liu C, Wang H., Free PMC Article

    03/20/2021
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