| CREB3 mediates the transcriptional regulation of PGC-1alpha, a master regulator of energy homeostasis and mitochondrial biogenesis. | CREB3 mediates the transcriptional regulation of PGC-1α, a master regulator of energy homeostasis and mitochondrial biogenesis.
Locke B, Campbell E, Lu R. | 08/22/2024 |
| ER stress-associated transcription factor CREB3 is essential for normal Ca[2+], ATP, and ROS homeostasis. | ER stress-associated transcription factor CREB3 is essential for normal Ca(2+), ATP, and ROS homeostasis.
Smith BS, Hewitt T, Bakovic M, Lu R. | 03/14/2023 |
| Transcription factor CREB3 is a potent regulator of high-fat diet-induced obesity and energy metabolism. | Transcription factor CREB3 is a potent regulator of high-fat diet-induced obesity and energy metabolism.
Smith BS, Diaguarachchige De Silva KH, Hashemi A, Duncan RE, Grapentine S, Bakovic M, Lu R. | 08/6/2022 |
| The role of small leucine zipper protein in osteoclastogenesis and its involvement in bone remodeling. | The role of small leucine zipper protein in osteoclastogenesis and its involvement in bone remodeling.
Kim S, Park S, Kang M, Ko J. | 01/9/2021 |
| Exploring the role of Luman/CREB3 in regulating decidualization of mice endometrial stromal cells by comparative transcriptomics. | Exploring the role of Luman/CREB3 in regulating decidualization of mice endometrial stromal cells by comparative transcriptomics.
Zhao F, Liu H, Wang N, Yu L, Wang A, Yi Y, Jin Y., Free PMC Article | 10/3/2020 |
| These findings suggest a model whereby SUMO regulates the distribution, oligomerization, and activity of oligomeric CPEB3, a critical player in the persistence of memory. | CPEB3 inhibits translation of mRNA targets by localizing them to P bodies.
Ford L, Ling E, Kandel ER, Fioriti L., Free PMC Article | 03/28/2020 |
| This finding is especially true for the unique action of the copper ion on CREB3 stabilization and processing in parallel to aberration of ubiquitin-proteasome system, which might provide new insights into understanding the mechanisms of intractable disorders. | Elucidating post-translational regulation of mouse CREB3 in Neuro2a cells.
Oh-Hashi K, Soga A, Naruse Y, Takahashi K, Kiuchi K, Hirata Y. | 11/3/2018 |
| LUMAN is a key regulator of glucocorticoid receptor-mediated signaling. | LUMAN/CREB3 is a key regulator of glucocorticoid-mediated stress responses.
Penney J, Mendell A, Zeng M, Tran K, Lymer J, Turner PV, Choleris E, MacLusky N, Lu R. | 09/30/2017 |
| Luman regulates mouse granulosa cell modulation of steroid synthesis, cell cycle activity and other regulators of folliculogenesis | Knockdown of CREB3/Luman by shRNA in Mouse Granulosa Cells Results in Decreased Estradiol and Progesterone Synthesis and Promotes Cell Proliferation.
Zhao F, Wang N, Yi Y, Lin P, Tang K, Wang A, Jin Y., Free PMC Article | 07/15/2017 |
| LRF seems to be involved in the regulation of decidualization during pregnancy. | Luman recruiting factor is involved in stromal cell proliferation during decidualization in mice.
Li X, Lin P, Chen F, Wang N, Zhao F, Wang A, Jin Y. | 05/20/2017 |
| These results suggest that Luman regulates the multinucleation of osteoclasts by promoting cell fusion of mononuclear osteoclasts through DC-STAMP induction and intracellular distribution during osteoclastogenesis. | Luman is involved in osteoclastogenesis through the regulation of DC-STAMP expression, stability and localization.
Kanemoto S, Kobayashi Y, Yamashita T, Miyamoto T, Cui M, Asada R, Cui X, Hino K, Kaneko M, Takai T, Matsuhisa K, Takahashi N, Imaizumi K., Free PMC Article | 09/10/2016 |
| sLZIP is a novel PPARgamma2 modulator for control of the balance between adipogenesis and osteogenesis during Mesenchymal stem cell differentiation | A novel PPARγ2 modulator sLZIP controls the balance between adipogenesis and osteogenesis during mesenchymal stem cell differentiation.
Kim J, Ko J., Free PMC Article | 06/20/2015 |
| sLZIP negatively regulates skeletal muscle differentiation via interaction with ACTN4. | Small leucine zipper protein (sLZIP) negatively regulates skeletal muscle differentiation via interaction with α-actinin-4.
An HT, Kim J, Yoo S, Ko J., Free PMC Article | 10/7/2014 |
| Luman might have important roles in embryo implantation and decidualization. | Expression and localization of Luman RNA and protein during mouse implantation and decidualization.
Lan X, Jin Y, Yang Y, Lin P, Hu L, Cui C, Li Q, Li X, Wang A. | 02/15/2014 |
| Luman recruiting factor might be involved in inducing apoptosis of granulosa cells through the endoplasmic reticulum stress pathway in mice | Luman recruiting factor regulates endoplasmic reticulum stress in mouse ovarian granulosa cell apoptosis.
Yang Y, Lin P, Chen F, Wang A, Lan X, Song Y, Jin Y. | 07/13/2013 |
| Data show that ApoA4 is a true target gene of LUMAN in bone marrow-derived DCs (BMDCs). | Analysis of genes regulated by the transcription factor LUMAN identifies ApoA4 as a target gene in dendritic cells.
Sanecka A, Ansems M, van Hout-Kuijer MA, Looman MW, Prosser AC, Welten S, Gilissen C, Sama IE, Huynen MA, Veltman JA, Jansen BJ, Eleveld-Trancikova D, Adema GJ. | 05/12/2012 |
| Luman/CREB3 recruitment factor inhibits Luman activation of the unfolded protein response | A novel protein, Luman/CREB3 recruitment factor, inhibits Luman activation of the unfolded protein response.
Audas TE, Li Y, Liang G, Lu R., Free PMC Article | 01/21/2010 |