| Loss of Calponin 2 causes premature ovarian insufficiency in mice. | Loss of Calponin 2 causes premature ovarian insufficiency in mice.
Hsieh TB, Jin JP., Free PMC Article | 02/15/2024 |
| Calponin 2 regulates ketogenesis to mitigate acute kidney injury. | Calponin 2 regulates ketogenesis to mitigate acute kidney injury.
Gui Y, Palanza Z, Gupta P, Li H, Pan Y, Wang Y, Hargis G, Kreutzer DL, Wang Y, Bastacky SI, Liu Y, Liu S, Zhou D., Free PMC Article | 11/14/2023 |
| Calponin 2 harnesses metabolic reprogramming to determine kidney fibrosis. | Calponin 2 harnesses metabolic reprogramming to determine kidney fibrosis.
Gui Y, Wang Y, Palanza Z, Wang JL, Gupta P, Tao J, Qiao Y, Hargis G, Kreutzer DL, Bastacky SI, Yu Y, Wang Y, Liu S, Fu H, Zhou D., Free PMC Article | 04/12/2023 |
| Loss of Calponin 2 causes age-progressive proteinuria in mice. | Loss of Calponin 2 causes age-progressive proteinuria in mice.
Hsieh TB, Jin JP., Free PMC Article | 10/8/2022 |
| Deletion of Calponin 2 Reduces the Formation of Postoperative Peritoneal Adhesions. | Deletion of Calponin 2 Reduces the Formation of Postoperative Peritoneal Adhesions.
Hsieh TB, Feng HZ, Jin JP., Free PMC Article | 03/5/2022 |
| A rapid degradation of calponin 2 is required for cytokinesis. | A rapid degradation of calponin 2 is required for cytokinesis.
Qian A, Hsieh TB, Hossain MM, Lin JJ, Jin JP., Free PMC Article | 09/25/2021 |
| Cnn1(-/-) and Cnn2(-/-) double knockout aortic smooth muscle exhibits faster relaxation than that of wild type control. | Double deletion of calponin 1 and calponin 2 in mice decreases systemic blood pressure with blunted length-tension response of aortic smooth muscle.
Feng HZ, Wang H, Takahashi K, Jin JP., Free PMC Article | 06/27/2020 |
| Cnn2 KO attenuated TGFb1-induced differentiation of myofibroblasts in culture as shown by the lower expression of SMA and less calcification than that of wild type (WT) cells. These findings present calponin 2 as a novel molecular target for the treatment and prevention of Calcific aortic valve | Deletion of calponin 2 attenuates the development of calcific aortic valve disease in ApoE(-/-) mice.
Plazyo O, Liu R, Moazzem Hossain M, Jin JP. | 09/14/2019 |
| Calponin 2-null macrophages and foam cells have significantly weakened cell adhesion, indicating a role of cytoskeleton regulation in macrophage functions and inflammatory responses, and a novel therapeutic target for the treatment of arterial atherosclerosis. | Deletion of calponin 2 in macrophages alters cytoskeleton-based functions and attenuates the development of atherosclerosis.
Liu R, Jin JP., Free PMC Article | 06/3/2017 |
| The novel finding that calponin 2 regulates myosin-dependent CTF in non-muscle cells demonstrates a mechanism for controlling cell motility-based functions | Deletion of Calponin 2 in Mouse Fibroblasts Increases Myosin II-Dependent Cell Traction Force.
Hossain MM, Zhao G, Woo MS, Wang JH, Jin JP. | 05/7/2017 |
| h2-Calponin gene expression is further affected by the treatment of cells with Notch inhibitor and activator, suggesting an upstream signaling mechanism. | Mechanoregulation of h2-calponin gene expression and the role of Notch signaling.
Jiang WR, Cady G, Hossain MM, Huang QQ, Wang X, Jin JP., Free PMC Article | 03/22/2014 |
| H2-calponin has a role in regulating macrophage motility and phagocytosis | Role of H2-calponin in regulating macrophage motility and phagocytosis.
Huang QQ, Hossain MM, Wu K, Parai K, Pope RM, Jin JP., Free PMC Article | 01/21/2010 |
| Expressed h2-calponin is associated with actin-tropomyosin microfilaments and may regulate cytokinesis by inhibiting the activity of the actin cytoskeleton. | Developmentally regulated expression of calponin isoforms and the effect of h2-calponin on cell proliferation.
Hossain MM, Hwang DY, Huang QQ, Sasaki Y, Jin JP. | 01/21/2010 |