| CADHERIN-11 regulation of myeloid phagocytes and autoimmune inflammation in murine lupus. | CADHERIN-11 regulation of myeloid phagocytes and autoimmune inflammation in murine lupus.
Chavula T, To S, Smith J, Pedroza M, Nimri J, Devaraj S, Wenderfer S, Vogel TP, Agarwal SK. | 05/31/2024 |
| Let-7c-3p suppresses lens epithelial-mesenchymal transition by inhibiting cadherin-11 expression in fibrotic cataract. | Let-7c-3p suppresses lens epithelial-mesenchymal transition by inhibiting cadherin-11 expression in fibrotic cataract.
Hou M, Luo F, Ding Y, Bao X, Chen X, Liu L, Wu M. | 04/17/2024 |
| Cadherin-11 and Its Role in Tissue Fibrosis. | Cadherin-11 and Its Role in Tissue Fibrosis.
Chavula T, To S, Agarwal SK. | 07/26/2023 |
| Cadherin-11 Regulates Macrophage Development and Function. | Cadherin-11 Regulates Macrophage Development and Function.
To S, Chavula T, Pedroza M, Smith J, Agarwal SK., Free PMC Article | 04/2/2022 |
| Dimerization of Cadherin-11 involves multi-site coupled unfolding and strand swapping. | Dimerization of Cadherin-11 involves multi-site coupled unfolding and strand swapping.
Koss H, Honig B, Shapiro L, Palmer AG 3rd., Free PMC Article | 03/19/2022 |
| Association of CDH11 with Autism Spectrum Disorder Revealed by Matched-gene Co-expression Analysis and Mouse Behavioral Studies. | Association of CDH11 with Autism Spectrum Disorder Revealed by Matched-gene Co-expression Analysis and Mouse Behavioral Studies.
Wu N, Wang Y, Jia JY, Pan YH, Yuan XB., Free PMC Article | 01/29/2022 |
| Impaired macrophage trafficking and increased helper T-cell recruitment with loss of cadherin-11 in atherosclerotic immune response. | Impaired macrophage trafficking and increased helper T-cell recruitment with loss of cadherin-11 in atherosclerotic immune response.
Johnson CL, Riley L, Bersi M, Linton MF, Merryman WD., Free PMC Article | 10/30/2021 |
| Regulation of Neural Circuit Development by Cadherin-11 Provides Implications for Autism. | Regulation of Neural Circuit Development by Cadherin-11 Provides Implications for Autism.
Frei JA, Niescier RF, Bridi MS, Durens M, Nestor JE, Kilander MBC, Yuan X, Dykxhoorn DM, Nestor MW, Huang S, Blatt GJ, Lin YC., Free PMC Article | 08/21/2021 |
| Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice. | Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice.
Peran I, Dakshanamurthy S, McCoy MD, Mavropoulos A, Allo B, Sebastian A, Hum NR, Sprague SC, Martin KA, Pishvaian MJ, Vietsch EE, Wellstein A, Atkins MB, Weiner LM, Quong AA, Loots GG, Yoo SS, Assefnia S, Byers SW., Free PMC Article | 08/7/2021 |
| Side-specific valvular endothelial-interstitial cell mechano-communication via cadherin-11. | Side-specific valvular endothelial-interstitial cell mechano-communication via cadherin-11.
Johnson CL, Merryman WD., Free PMC Article | 06/12/2021 |
| Cadherin-11 blockade reduces inflammation-driven fibrotic remodeling and improves outcomes after myocardial infarction. | Cadherin-11 blockade reduces inflammation-driven fibrotic remodeling and improves outcomes after myocardial infarction.
Schroer AK, Bersi MR, Clark CR, Zhang Q, Sanders LH, Hatzopoulos AK, Force TL, Majka SM, Lal H, Merryman WD., Free PMC Article | 10/3/2020 |
| mRNA expression profiles of two autism spectrum disorder-associated cadherins, Cdh9 and Cdh11, in the developing cerebellum, were examined. | Segregated expressions of autism risk genes Cdh11 and Cdh9 in autism-relevant regions of developing cerebellum.
Wang C, Pan YH, Wang Y, Blatt G, Yuan XB., Free PMC Article | 05/30/2020 |
| Cadherin 11 (Cdh11) establishes proximity for macrophages and myofibroblasts (MFs) that enhances local amounts of active transforming growth factor-beta (TGF-beta1). | Cadherin-11-mediated adhesion of macrophages to myofibroblasts establishes a profibrotic niche of active TGF-β.
Lodyga M, Cambridge E, Karvonen HM, Pakshir P, Wu B, Boo S, Kiebalo M, Kaarteenaho R, Glogauer M, Kapoor M, Ask K, Hinz B. | 03/28/2020 |
| These data demonstrate that CDH11 is increased during liver fibrosis, is an important regulator of liver fibrosis induced by CCL4 and suggest that CDH11 may be a potential therapeutic target for liver fibrosis | Cadherin-11 contributes to liver fibrosis induced by carbon tetrachloride.
Pedroza M, To S, Smith J, Agarwal SK., Free PMC Article | 02/22/2020 |
| Cadherin-11 influences valvular interstitial cell contractility by regulating focal adhesions and inflammatory cytokine secretion. | Cadherin-11 as a regulator of valve myofibroblast mechanobiology.
Bowler MA, Bersi MR, Ryzhova LM, Jerrell RJ, Parekh A, Merryman WD., Free PMC Article | 09/14/2019 |
| may be directly involved in middle ear cavitation | The adhesion molecule cadherin 11 is essential for acquisition of normal hearing ability through middle ear development in the mouse.
Kiyama Y, Kikkawa YS, Kinoshita M, Matsumoto Y, Kondo K, Fujimoto C, Iwasaki S, Yamasoba T, Manabe T. | 06/15/2019 |
| CDH11 promotes liver fibrosis by activating hepatic stellate cells | CDH11 promotes liver fibrosis via activation of hepatic stellate cells.
Ruan W, Pan R, Shen X, Nie Y, Wu Y. | 06/8/2019 |
| Targeting Cadherin-11 Prevents Notch1-Mediated Calcific Aortic Valve Disease. | Targeting Cadherin-11 Prevents Notch1-Mediated Calcific Aortic Valve Disease.
Clark CR, Bowler MA, Snider JC, Merryman WD., Free PMC Article | 01/19/2019 |
| Expression of cadherin-11, an adhesion molecule known to promote cell migration and compaction, was upregulated by intermediate-dose BMP7. BMP7-induced cadherin-11 expression was inhibited by cotreatment with SB203580 and PD98059. | BMP7 dose-dependently stimulates proliferation and cadherin-11 expression via ERK and p38 in a murine metanephric mesenchymal cell line.
Awazu M, Nagata M, Hida M., Free PMC Article | 05/5/2018 |
| data demonstrate an important role for CDH11 in the development of skin fibrosis in Tsk-1 mice. These data add to the growing evidence for the important role of CDH11 in tissue fibrosis and fibrotic disease such as systemic sclerosis | Targeting of cadherin-11 decreases skin fibrosis in the tight skin-1 mouse model.
Pedroza M, Welschhans RL, Agarwal SK., Free PMC Article | 12/2/2017 |
| stromal fibroblasts expressing cadherin-11 regulate adipose tissue inflammation | Stromal cell cadherin-11 regulates adipose tissue inflammation and diabetes.
Chang SK, Kohlgruber AC, Mizoguchi F, Michelet X, Wolf BJ, Wei K, Lee PY, Lynch L, Duquette D, Ceperuelo-Mallafré V, Banks AS, Brenner MB., Free PMC Article | 10/28/2017 |
| engagement of CDH11 through homophilic interactions, led to swift activation of the TGF-beta and ROCK pathways as evidenced by phosphorylation of downstream effectors. | Cadherin-11 is a novel regulator of extracellular matrix synthesis and tissue mechanics.
Row S, Liu Y, Alimperti S, Agarwal SK, Andreadis ST., Free PMC Article | 08/5/2017 |
| Loss of CDH11 gene is associated with retinoblastoma. | Genomic landscape of retinoblastoma in Rb(-/-) p130(-/-) mice resembles human retinoblastoma.
Kooi IE, van Mil SE, MacPherson D, Mol BM, Moll AC, Meijers-Heijboer H, Kaspers GJ, Cloos J, Te Riele H, Dorsman JC. | 07/22/2017 |
| Overexpression of Cad-11 upregulates RhoA and Sox9 to induce calcification and extracellular matrix remodeling in adult aortic valves. | Cadherin-11 Overexpression Induces Extracellular Matrix Remodeling and Calcification in Mature Aortic Valves.
Sung DC, Bowen CJ, Vaidya KA, Zhou J, Chapurin N, Recknagel A, Zhou B, Chen J, Kotlikoff M, Butcher JT., Free PMC Article | 06/24/2017 |
| Cad-11 depleted cells in culture contained few filopodia, stress fibers, or contact inhibited locomotion | Cadherin-11 coordinates cellular migration and extracellular matrix remodeling during aortic valve maturation.
Bowen CJ, Zhou J, Sung DC, Butcher JT., Free PMC Article | 02/27/2016 |