| The actin-binding protein CAP1 represses MRTF-SRF-dependent gene expression in mouse cerebral cortex. | The actin-binding protein CAP1 represses MRTF-SRF-dependent gene expression in mouse cerebral cortex.
Khudayberdiev S, Weiss K, Heinze A, Colombaretti D, Trausch N, Linne U, Rust MB. | 06/3/2024 |
| Cyclase-associated protein interacts with actin filament barbed ends to promote depolymerization and formin displacement. | Cyclase-associated protein interacts with actin filament barbed ends to promote depolymerization and formin displacement.
Alimov N, Hoeprich GJ, Padrick SB, Goode BL., Free PMC Article | 01/9/2024 |
| Loss of the actin regulator cyclase-associated protein 1 (CAP1) modestly affects dendritic spine remodeling during synaptic plasticity. | Loss of the actin regulator cyclase-associated protein 1 (CAP1) modestly affects dendritic spine remodeling during synaptic plasticity.
Heinze A, Rust MB. | 12/1/2023 |
| Functional Redundancy of Cyclase-Associated Proteins CAP1 and CAP2 in Differentiating Neurons. | Functional Redundancy of Cyclase-Associated Proteins CAP1 and CAP2 in Differentiating Neurons.
Schneider F, Metz I, Khudayberdiev S, Rust MB., Free PMC Article | 10/30/2021 |
| CAP1, a target of miR-144/451, negatively regulates erythroid differentiation and enucleation. | CAP1, a target of miR-144/451, negatively regulates erythroid differentiation and enucleation.
Huang X, Chao R, Zhang Y, Wang P, Gong X, Liang D, Wang Y., Free PMC Article | 09/25/2021 |
| Results provide evidence for the importance of dynamic actin recycling by CAP1 and cofilin in the asymmetric division of mouse female gametes. | CAP1-mediated actin cycling via ADF/cofilin proteins is essential for asymmetric division in mouse oocytes.
Jin ZL, Jo YJ, Namgoong S, Kim NH. | 12/7/2019 |
| we purified an INF2 inhibitor from mouse brain tissue, and identified it as a complex of lysine-acetylated actin (KAc-actin) and cyclase-associated protein (CAP). Inhibition of INF2 by CAP-KAc-actin is dependent on the INF2 diaphanous inhibitory domain (DID). | A complex containing lysine-acetylated actin inhibits the formin INF2.
A M, Fung TS, Kettenbach AN, Chakrabarti R, Higgs HN., Free PMC Article | 07/6/2019 |
| The structural basis of actin monomer re-charging by CAP1 protein has been reported. | Structural basis of actin monomer re-charging by cyclase-associated protein.
Kotila T, Kogan K, Enkavi G, Guo S, Vattulainen I, Goode BL, Lappalainen P., Free PMC Article | 12/1/2018 |
| Phosphorylation regulates CAP1 function through association with cofilin and actin in order to control the actin cytoskeleton. | Phosphorylation of the cytoskeletal protein CAP1 controls its association with cofilin and actin.
Zhou GL, Zhang H, Wu H, Ghai P, Field J., Free PMC Article | 07/25/2015 |
| a novel inhibitory interaction between CAP1/Prss8 and nexin-1, opening the search for specific CAP1/Prss8 antagonists that are independent of its catalytic activity | The CAP1/Prss8 catalytic triad is not involved in PAR2 activation and protease nexin-1 (PN-1) inhibition.
Crisante G, Battista L, Iwaszkiewicz J, Nesca V, Mérillat AM, Sergi C, Zoete V, Frateschi S, Hummler E. | 01/31/2015 |
| lkj o hpoi oihl hip oihpo ih | Structure and mechanism of mouse cyclase-associated protein (CAP1) in regulating actin dynamics.
Jansen S, Collins A, Golden L, Sokolova O, Goode BL., Free PMC Article | 01/3/2015 |
| CAP1 depletion also led to changes in cofilin phosphorylation and localization as well as activation of focal adhesion kinase (FAK) and enhanced cell spreading. | Mammalian adenylyl cyclase-associated protein 1 (CAP1) regulates cofilin function, the actin cytoskeleton, and cell adhesion.
Zhang H, Ghai P, Wu H, Wang C, Field J, Zhou GL., Free PMC Article | 11/30/2013 |
| study provides evidence that catalyzing nucleotide exchange on actin monomers via the beta-sheet domain is the most highly conserved function of CAPs from mammals to apicomplexan parasites. | Mammalian and malaria parasite cyclase-associated proteins catalyze nucleotide exchange on G-actin through a conserved mechanism.
Makkonen M, Bertling E, Chebotareva NA, Baum J, Lappalainen P., Free PMC Article | 03/30/2013 |
| These studies suggest that CAP1 provides a direct link from the actin cytoskeleton to the mitochondria by functioning as an actin shuttle. | Mitochondrial shuttling of CAP1 promotes actin- and cofilin-dependent apoptosis.
Wang C, Zhou GL, Vedantam S, Li P, Field J., Free PMC Article | 01/21/2010 |
| Postsynaptic adenylyl cyclase 1 is required for functional maturation of thalamocortical synapses and morphological barrels. | Cortical adenylyl cyclase 1 is required for thalamocortical synapse maturation and aspects of layer IV barrel development.
Iwasato T, Inan M, Kanki H, Erzurumlu RS, Itohara S, Crair MC., Free PMC Article | 01/21/2010 |
| CAP1 shows a broad tissue distribution and localizes to the cytoplasm | CAP2, cyclase-associated protein 2, is a dual compartment protein.
Peche V, Shekar S, Leichter M, Korte H, Schröder R, Schleicher M, Holak TA, Clemen CS, Ramanath-Y B, Pfitzer G, Karakesisoglou I, Noegel AA., Free PMC Article | 01/21/2010 |
| CAP1 is widely expressed in mouse nonmuscle cells and promotes cofilin-induced actin dynamics. | Cyclase-associated protein 1 (CAP1) promotes cofilin-induced actin dynamics in mammalian nonmuscle cells.
Bertling E, Hotulainen P, Mattila PK, Matilainen T, Salminen M, Lappalainen P., Free PMC Article | 01/21/2010 |