| Hypothyroidism alters the rhythmicity of the central clock, body temperature and metabolism: evidence of Bmal1 transcriptional regulation by T3. | Hypothyroidism alters the rhythmicity of the central clock, body temperature and metabolism: evidence of Bmal1 transcriptional regulation by T3.
Emrich F, Gomes BH, Selvatici-Tolentino L, Lopes RA, Secio-Silva A, Carvalho-Moreira JP, Bittencourt-Silva PG, Guarnieri LO, Silva ABP, Drummond LR, da Silva GSF, Szawka RE, Moraes MFD, Coimbra CC, Peliciari-Garcia RA, Bargi-Souza P. | 10/10/2024 |
| Deletion of Bmal1 in aggrecan-expressing cells leads to mouse temporomandibular joint osteoarthritis. | Deletion of Bmal1 in aggrecan-expressing cells leads to mouse temporomandibular joint osteoarthritis.
Liao L, Yang L, Li Y, Hu J, Lu H, Liu H, Huang J, He L, Meng Z, Liang J, Chen D, Zhou Q, Chang X, Wu S. | 10/7/2024 |
| Hepatic BMAL1 and HIF1alpha regulate a time-dependent hypoxic response and prevent hepatopulmonary-like syndrome. | Hepatic BMAL1 and HIF1α regulate a time-dependent hypoxic response and prevent hepatopulmonary-like syndrome.
Dandavate V, Bolshette N, Van Drunen R, Manella G, Bueno-Levy H, Zerbib M, Kawano I, Golik M, Adamovich Y, Asher G. | 09/12/2024 |
| BMAL1 plays a crucial role in immune homeostasis during sepsis-induced acute lung injury. | BMAL1 plays a crucial role in immune homeostasis during sepsis-induced acute lung injury.
Zeng T, Liang L, Deng W, Xie M, Zhao M, Wang S, Liu J, Yang M. | 08/28/2024 |
| Skeletal muscle BMAL1 is necessary for transcriptional adaptation of local and peripheral tissues in response to endurance exercise training. | Skeletal muscle BMAL1 is necessary for transcriptional adaptation of local and peripheral tissues in response to endurance exercise training.
Viggars MR, Berko HE, Hesketh SJ, Wolff CA, Gutierrez-Monreal MA, Martin RA, Jennings IG, Huo Z, Esser KA., Free PMC Article | 08/20/2024 |
| Sleep deprivation induces corneal endothelial dysfunction by downregulating Bmal1. | Sleep deprivation induces corneal endothelial dysfunction by downregulating Bmal1.
Wang Y, Wang Q, Dou S, Zhou Q, Xie L., Free PMC Article | 07/19/2024 |
| Bmal1 regulates female reproduction in mice via the hypothalamic-pituitary-ovarian axis. | Bmal1 regulates female reproduction in mice via the hypothalamic-pituitary-ovarian axis.
Zhang A, Li S, Huang L, Jiang Y, Chen Y, Zhu S, Xiong F, Luo Z, Ou M, Ying J, Wang S, Mu D, Qu Y. | 07/16/2024 |
| Circadian rhythm disruption-mediated downregulation of Bmal1 exacerbates DSS-induced colitis by impairing intestinal barrier. | Circadian rhythm disruption-mediated downregulation of Bmal1 exacerbates DSS-induced colitis by impairing intestinal barrier.
Zhang Z, Li W, Han X, Tian D, Yan W, Liu M, Cao L., Free PMC Article | 07/8/2024 |
| Metabolic Profile and Lipid Metabolism Phenotype in Mice with Conditional Deletion of Hepatic BMAL1. | Metabolic Profile and Lipid Metabolism Phenotype in Mice with Conditional Deletion of Hepatic BMAL1.
Gu W, Li T, Huang Y, Wang R, Zhang L, Chen R, Li R, Liu C., Free PMC Article | 07/3/2024 |
| BMAL1 sex-specific effects in the neonatal mouse airway exposed to moderate hyperoxia. | BMAL1 sex-specific effects in the neonatal mouse airway exposed to moderate hyperoxia.
Bartman CM, Nesbitt L, Lee KK, Khalfaoui L, Fang YH, Pabelick CM, Prakash YS., Free PMC Article | 07/2/2024 |
| Phosphorylation of DNA-binding domains of CLOCK-BMAL1 complex for PER-dependent inhibition in circadian clock of mammalian cells. | Phosphorylation of DNA-binding domains of CLOCK-BMAL1 complex for PER-dependent inhibition in circadian clock of mammalian cells.
Otobe Y, Jeong EM, Ito S, Shinohara Y, Kurabayashi N, Aiba A, Fukada Y, Kim JK, Yoshitane H., Free PMC Article | 06/12/2024 |
| BMAL1 deletion protects against obesity and non-alcoholic fatty liver disease induced by a high-fat diet. | BMAL1 deletion protects against obesity and non-alcoholic fatty liver disease induced by a high-fat diet.
Zhan C, Chen H, Zhang Z, Shao Y, Xu B, Hua R, Yao Q, Liu W, Shen Q. | 04/2/2024 |
| Autistic-like behavior and cerebellar dysfunction in Bmal1 mutant mice ameliorated by mTORC1 inhibition. | Autistic-like behavior and cerebellar dysfunction in Bmal1 mutant mice ameliorated by mTORC1 inhibition.
Liu D, Nanclares C, Simbriger K, Fang K, Lorsung E, Le N, Amorim IS, Chalkiadaki K, Pathak SS, Li J, Gewirtz JC, Jin VX, Kofuji P, Araque A, Orr HT, Gkogkas CG, Cao R., Free PMC Article | 02/23/2024 |
| Mutations of the circadian clock genes Cry, Per, or Bmal1 have different effects on the transcribed and nontranscribed strands of cycling genes. | Mutations of the circadian clock genes Cry, Per, or Bmal1 have different effects on the transcribed and nontranscribed strands of cycling genes.
Yang Y, Wu G, Sancar A, Hogenesch JB., Free PMC Article | 02/20/2024 |
| miR-155-5p/Bmal1 Modulates the Senescence and Osteogenic Differentiation of Mouse BMSCs through the Hippo Signaling Pathway. | miR-155-5p/Bmal1 Modulates the Senescence and Osteogenic Differentiation of Mouse BMSCs through the Hippo Signaling Pathway.
Zhang L, Zhang C, Zheng J, Wang Y, Wei X, Yang Y, Zhao Q., Free PMC Article | 02/12/2024 |
| Sleep deprivation reduced LPS-induced IgG2b production by up-regulating BMAL1 and CLOCK expression. | Sleep deprivation reduced LPS-induced IgG2b production by up-regulating BMAL1 and CLOCK expression.
Xing C, Zhai B, Zhang Y, Fang Y, Zhang M, Zhang C, Wang W, Ding M, Huang X, Shen B, Wang R, Song L. | 02/12/2024 |
| Identification of BMAL1-Regulated circadian genes in mouse liver and their potential association with hepatocellular carcinoma: Gys2 and Upp2 as promising candidates. | Identification of BMAL1-Regulated circadian genes in mouse liver and their potential association with hepatocellular carcinoma: Gys2 and Upp2 as promising candidates.
Zhao H, Han G, Jiang Z, Gao D, Zhang H, Yang L, Ma T, Gao L, Wang A, Chao HW, Li Q, Jin Y, Chen H. | 02/9/2024 |
| Circadian misalignment impairs oligodendrocyte myelination via Bmal1 overexpression leading to anxiety and depression-like behaviors. | Circadian misalignment impairs oligodendrocyte myelination via Bmal1 overexpression leading to anxiety and depression-like behaviors.
Zuo Y, Hou Y, Wang Y, Yuan L, Cheng L, Zhang T. | 02/8/2024 |
| Neuronal deletion of the circadian clock gene Bmal1 induces cell-autonomous dopaminergic neurodegeneration. | Neuronal deletion of the circadian clock gene Bmal1 induces cell-autonomous dopaminergic neurodegeneration.
Kanan MF, Sheehan PW, Haines JN, Gomez PG, Dhuler A, Nadarajah CJ, Wargel ZM, Freeberg BM, Nelvagal HR, Izumo M, Takahashi JS, Cooper JD, Davis AA, Musiek ES., Free PMC Article | 02/2/2024 |
| Acute exercise modulates Trim63 and Bmal1 in the skeletal muscle of IL-10 knockout mice. | Acute exercise modulates Trim63 and Bmal1 in the skeletal muscle of IL-10 knockout mice.
da Mata GE, Bricola R, Ribeiro DN, Simabuco FM, Pauli JR, de Freitas EC, Ropelle ER, da Silva ASR, Pinto AP. | 02/2/2024 |
| Cell state dependent effects of Bmal1 on melanoma immunity and tumorigenicity. | Cell state dependent effects of Bmal1 on melanoma immunity and tumorigenicity.
Zhang X, Pant SM, Ritch CC, Tang HY, Shao H, Dweep H, Gong YY, Brooks R, Brafford P, Wolpaw AJ, Lee Y, Weeraratna A, Sehgal A, Herlyn M, Kossenkov A, Speicher D, Sorger PK, Santagata S, Dang CV., Free PMC Article | 02/1/2024 |
| iMS-Bmal1[-/-] mice show evident signs of sarcopenia that are counteracted by exercise and melatonin therapies. | iMS-Bmal1(-/-) mice show evident signs of sarcopenia that are counteracted by exercise and melatonin therapies.
Fernández-Martínez J, Ramírez-Casas Y, Aranda-Martínez P, López-Rodríguez A, Sayed RKA, Escames G, Acuña-Castroviejo D. | 01/26/2024 |
| Myeloid Bmal1 deletion suppresses the house dust mite-induced chronic lung allergy. | Myeloid Bmal1 deletion suppresses the house dust mite-induced chronic lung allergy.
Hong H, Zhang J, Cao X, Wu Y, Chan TF, Tian XY. | 01/8/2024 |
| Deficiency of BMAL1 promotes ROS generation and enhances IgE-dependent degranulation in mast cells. | Deficiency of BMAL1 promotes ROS generation and enhances IgE-dependent degranulation in mast cells.
Nagasaka Y, Nakamura Y, Tran NQV, Kobayashi Y, Nakano N, Nakao A. | 01/5/2024 |
| BMAL1 loss in oligodendroglia contributes to abnormal myelination and sleep. | BMAL1 loss in oligodendroglia contributes to abnormal myelination and sleep.
Rojo D, Dal Cengio L, Badner A, Kim S, Sakai N, Greene J, Dierckx T, Mehl LC, Eisinger E, Ransom J, Arellano-Garcia C, Gumma ME, Soyk RL, Lewis CM, Lam M, Weigel MK, Damonte VM, Yalçın B, Jones SE, Ollila HM, Nishino S, Gibson EM., Free PMC Article | 12/15/2023 |