Potential i-Nos/Arg-1 Switch with NLRP3 and Parasitic Load Down Regulation in Experimental Schistosoma mansoni Infection via Chloroquine Repurposing. | Potential i-Nos/Arg-1 Switch with NLRP3 and Parasitic Load Down Regulation in Experimental Schistosoma mansoni Infection via Chloroquine Repurposing. Hasby Saad MA, El-Saadi EG, Ali DA, Watany MM, Eid MM. | 03/20/2024 |
Arginase 1 does not affect RNA m6A methylation in mouse fetal lung. | Arginase 1 does not affect RNA m6A methylation in mouse fetal lung. Sui X, Sui Y, Long P, Wang Y, Chen Y, Zhai W, Gao L. | 02/20/2024 |
DDR2-regulated arginase activity in ovarian cancer-associated fibroblasts promotes collagen production and tumor progression. | DDR2-regulated arginase activity in ovarian cancer-associated fibroblasts promotes collagen production and tumor progression. Akinjiyan FA, Ibitoye Z, Zhao P, Shriver LP, Patti GJ, Longmore GD, Fuh KC., Free PMC Article | 01/27/2024 |
Methylglyoxal-Modified Albumin Effects on Endothelial Arginase Enzyme and Vascular Function. | Methylglyoxal-Modified Albumin Effects on Endothelial Arginase Enzyme and Vascular Function. Alzayadneh EM, Shatanawi A, Caldwell RW, Caldwell RB., Free PMC Article | 10/26/2023 |
Arginase-1 promotes lens epithelial-to-mesenchymal transition in different models of anterior subcapsular cataract. | Arginase-1 promotes lens epithelial-to-mesenchymal transition in different models of anterior subcapsular cataract. Li Q, Wang Y, Shi L, Wang Q, Yang G, Deng L, Tian Y, Hua X, Yuan X., Free PMC Article | 09/28/2023 |
Loss of CD4[+] T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection. | Loss of CD4(+) T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection. West EE, Merle NS, Kamiński MM, Palacios G, Kumar D, Wang L, Bibby JA, Overdahl K, Jarmusch AK, Freeley S, Lee DY, Thompson JW, Yu ZX, Taylor N, Sitbon M, Green DR, Bohrer A, Mayer-Barber KD, Afzali B, Kazemian M, Scholl-Buergi S, Karall D, Huemer M, Kemper C., Free PMC Article | 09/18/2023 |
Inhibitory IL-10-producing CD4[+] T cells are T-bet-dependent and facilitate cytomegalovirus persistence via coexpression of arginase-1. | Inhibitory IL-10-producing CD4(+) T cells are T-bet-dependent and facilitate cytomegalovirus persistence via coexpression of arginase-1. Clement M, Ladell K, Miners KL, Marsden M, Chapman L, Cardus Figueras A, Scott J, Andrews R, Clare S, Kriukova VV, Lupyr KR, Britanova OV, Withers DR, Jones SA, Chudakov DM, Price DA, Humphreys IR., Free PMC Article | 08/31/2023 |
Arginase 1 and L-arginine coordinate fetal lung development and the initiation of labor in mice. | Arginase 1 and L-arginine coordinate fetal lung development and the initiation of labor in mice. Yu Y, Liu Y, Sui X, Sui Y, Wang Z, Mendelson CR, Gao L., Free PMC Article | 08/4/2023 |
Arginase 1 is a key driver of immune suppression in pancreatic cancer. | Arginase 1 is a key driver of immune suppression in pancreatic cancer. Menjivar RE, Nwosu ZC, Du W, Donahue KL, Hong HS, Espinoza C, Brown K, Velez-Delgado A, Yan W, Lima F, Bischoff A, Kadiyala P, Salas-Escabillas D, Crawford HC, Bednar F, Carpenter E, Zhang Y, Halbrook CJ, Lyssiotis CA, Pasca di Magliano M., Free PMC Article | 06/22/2023 |
ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain. | ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain. Stratoulias V, Ruiz R, Kanatani S, Osman AM, Keane L, Armengol JA, Rodríguez-Moreno A, Murgoci AN, García-Domínguez I, Alonso-Bellido I, González Ibáñez F, Picard K, Vázquez-Cabrera G, Posada-Pérez M, Vernoux N, Tejera D, Grabert K, Cheray M, González-Rodríguez P, Pérez-Villegas EM, Martínez-Gallego I, Lastra-Romero A, Brodin D, Avila-Cariño J, Cao Y, Airavaara M, Uhlén P, Heneka MT, Tremblay MÈ, Blomgren K, Venero JL, Joseph B., Free PMC Article | 06/9/2023 |
Autophagic reprogramming of bone marrow-derived macrophages. | Autophagic reprogramming of bone marrow-derived macrophages. Mazher M, Moqidem YA, Zidan M, Sayed AA, Abdellatif A., Free PMC Article | 04/5/2023 |
Arginase 1 Expression by Macrophages Promotes Cryptococcus neoformans Proliferation and Invasion into Brain Microvascular Endothelial Cells. | Arginase 1 Expression by Macrophages Promotes Cryptococcus neoformans Proliferation and Invasion into Brain Microvascular Endothelial Cells. Hansakon A, Ngamphiw C, Tongsima S, Angkasekwinai P. | 02/11/2023 |
Arginase-1 Deletion in Erythrocytes Promotes Vascular Calcification via Enhanced GSNOR (S-Nitrosoglutathione Reductase) Expression and NO Signaling in Smooth Muscle Cells. | Arginase-1 Deletion in Erythrocytes Promotes Vascular Calcification via Enhanced GSNOR (S-Nitrosoglutathione Reductase) Expression and NO Signaling in Smooth Muscle Cells. Gogiraju R, Renner L, Bochenek ML, Zifkos K, Molitor M, Danckwardt S, Wenzel P, Münzel T, Konstantinides S, Schäfer K. | 11/26/2022 |
Arginase-1 Is Required for Macrophage-Mediated Renal Tubule Regeneration. | Arginase-1 Is Required for Macrophage-Mediated Renal Tubule Regeneration. Shin NS, Marlier A, Xu L, Doilicho N, Linberg D, Guo J, Cantley LG., Free PMC Article | 06/11/2022 |
Metabolomic Analysis of Diverse Mice Reveals Hepatic Arginase-1 as Source of Plasma Arginase in Plasmodium chabaudi Infection. | Metabolomic Analysis of Diverse Mice Reveals Hepatic Arginase-1 as Source of Plasma Arginase in Plasmodium chabaudi Infection. Davis NM, Lissner MM, Richards CL, Chevée V, Gupta AS, Gherardini FC, Schneider DS., Free PMC Article | 01/29/2022 |
Myeloid arginase-1 controls excessive inflammation and modulates T cell responses in Pseudomonas aeruginosa pneumonia. | Myeloid arginase-1 controls excessive inflammation and modulates T cell responses in Pseudomonas aeruginosa pneumonia. Haydar D, Gonzalez R, Garvy BA, Garneau-Tsodikova S, Thamban Chandrika N, Bocklage TJ, Feola DJ., Free PMC Article | 01/29/2022 |
Carbon Monoxide Regulates Macrophage Differentiation and Polarization toward the M2 Phenotype through Upregulation of Heme Oxygenase 1. | Carbon Monoxide Regulates Macrophage Differentiation and Polarization toward the M2 Phenotype through Upregulation of Heme Oxygenase 1. Kang IS, Kim RI, Kim C., Free PMC Article | 01/22/2022 |
Arginase-1 deficiency in neural cells does not contribute to neurodevelopment or functional outcomes after sciatic nerve injury. | Arginase-1 deficiency in neural cells does not contribute to neurodevelopment or functional outcomes after sciatic nerve injury. Richmond CR, Ballantyne LL, de Guzman AE, Nieman BJ, Funk CD, Ghasemlou N. | 11/22/2021 |
Murine Susceptibility to Leishmania amazonensis Infection Is Influenced by Arginase-1 and Macrophages at the Lesion Site. | Murine Susceptibility to Leishmania amazonensis Infection Is Influenced by Arginase-1 and Macrophages at the Lesion Site. Tomiotto-Pellissier F, Miranda-Sapla MM, Silva TF, Bortoleti BTDS, Gonçalves MD, Concato VM, Rodrigues ACJ, Detoni MB, Costa IN, Panis C, Conchon-Costa I, Bordignon J, Pavanelli WR., Free PMC Article | 10/30/2021 |
Cytokine-Mediated Regulation of ARG1 in Macrophages and Its Impact on the Control of Salmonella enterica Serovar Typhimurium Infection. | Cytokine-Mediated Regulation of ARG1 in Macrophages and Its Impact on the Control of Salmonella enterica Serovar Typhimurium Infection. Brigo N, Pfeifhofer-Obermair C, Tymoszuk P, Demetz E, Engl S, Barros-Pinkelnig M, Dichtl S, Fischer C, Valente De Souza L, Petzer V, von Raffay L, Hilbe R, Berger S, Seifert M, Schleicher U, Bogdan C, Weiss G., Free PMC Article | 10/30/2021 |
Myeloid Arginase 1 Insufficiency Exacerbates Amyloid-beta Associated Neurodegenerative Pathways and Glial Signatures in a Mouse Model of Alzheimer's Disease: A Targeted Transcriptome Analysis. | Myeloid Arginase 1 Insufficiency Exacerbates Amyloid-β Associated Neurodegenerative Pathways and Glial Signatures in a Mouse Model of Alzheimer's Disease: A Targeted Transcriptome Analysis. Ma C, Hunt JB, Kovalenko A, Liang H, Selenica MB, Orr MB, Zhang B, Gensel JC, Feola DJ, Gordon MN, Morgan D, Bickford PC, Lee DC., Free PMC Article | 09/18/2021 |
Arginase 1 Insufficiency Precipitates Amyloid-beta Deposition and Hastens Behavioral Impairment in a Mouse Model of Amyloidosis. | Arginase 1 Insufficiency Precipitates Amyloid-β Deposition and Hastens Behavioral Impairment in a Mouse Model of Amyloidosis. Ma C, Hunt JB, Selenica MB, Sanneh A, Sandusky-Beltran LA, Watler M, Daas R, Kovalenko A, Liang H, Placides D, Cao C, Lin X, Orr MB, Zhang B, Gensel JC, Feola DJ, Gordon MN, Morgan D, Bickford PC, Lee DC., Free PMC Article | 06/26/2021 |
Increased Arginase1 expression in tumor microenvironment promotes mammary carcinogenesis via multiple mechanisms. | Increased Arginase1 expression in tumor microenvironment promotes mammary carcinogenesis via multiple mechanisms. Croce M, Damonte P, Morini M, Pigozzi S, Chiossone L, Vacca P, Bronte V, Barbieri O, Astigiano S. | 05/22/2021 |
HGF-MET Signaling Shifts M1 Macrophages Toward an M2-Like Phenotype Through PI3K-Mediated Induction of Arginase-1 Expression. | HGF-MET Signaling Shifts M1 Macrophages Toward an M2-Like Phenotype Through PI3K-Mediated Induction of Arginase-1 Expression. Nishikoba N, Kumagai K, Kanmura S, Nakamura Y, Ono M, Eguchi H, Kamibayashiyama T, Oda K, Mawatari S, Tanoue S, Hashimoto S, Tsubouchi H, Ido A., Free PMC Article | 05/8/2021 |
Myeloid-Derived Suppressor Cell-Derived Arginase-1 Oppositely Modulates IL-17A and IL-17F Through the ESR/STAT3 Pathway During Colitis in Mice. | Myeloid-Derived Suppressor Cell-Derived Arginase-1 Oppositely Modulates IL-17A and IL-17F Through the ESR/STAT3 Pathway During Colitis in Mice. Ma Z, Zhen Y, Hu C, Yi H., Free PMC Article | 04/3/2021 |