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    MUCL1 mucin like 1 [ Homo sapiens (human) ]

    Gene ID: 118430, updated on 10-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    miRNA-186-5p inhibits migration, invasion and proliferation of breast cancer cells by targeting SBEM.

    miRNA-186-5p inhibits migration, invasion and proliferation of breast cancer cells by targeting SBEM.
    Hao H, Wang B, Yang L, Sang Y, Xu W, Liu W, Zhang L, Jiang D., Free PMC Article

    08/7/2023
    The mucin protein MUCL1 regulates melanogenesis and melanoma genes in a manner dependent on threonine content.

    The mucin protein MUCL1 regulates melanogenesis and melanoma genes in a manner dependent on threonine content.
    Kim J, Choi H., Free PMC Article

    04/30/2022
    Targeting MUCL1 protein inhibits cell proliferation and EMT by deregulating betacatenin and increases irinotecan sensitivity in colorectal cancer.

    Targeting MUCL1 protein inhibits cell proliferation and EMT by deregulating β‑catenin and increases irinotecan sensitivity in colorectal cancer.
    Abdulla M, Traiki TB, Vaali-Mohammed MA, El-Wetidy MS, Alhassan N, Al-Khayal K, Zubaidi A, Al-Obeed O, Ahmad R., Free PMC Article

    03/26/2022
    Small breast epithelial mucin promotes the invasion and metastasis of breast cancer cells via promoting epithelialtomesenchymal transition.

    Small breast epithelial mucin promotes the invasion and metastasis of breast cancer cells via promoting epithelial‑to‑mesenchymal transition.
    Li QH, Liu ZZ, Ge YΝ, Liu X, Xie XD, Zheng ZD, Ma YH, Liu B., Free PMC Article

    05/8/2021
    an important role for MUCL1 in the proliferation of breast cancer cells

    HER2 drives Mucin-like 1 to control proliferation in breast cancer cells.
    Conley SJ, Bosco EE, Tice DA, Hollingsworth RE, Herbst R, Xiao Z., Free PMC Article

    08/19/2017
    SBEM has the potential to be a specific marker for predicting hematogenous micrometastasis and response to neoadjuvant chemotherapy in breast cancer.

    Small breast epithelial mucin (SBEM) has the potential to be a marker for predicting hematogenous micrometastasis and response to neoadjuvant chemotherapy in breast cancer.
    Liu ZZ, Xie XD, Qu SX, Zheng ZD, Wang YK.

    06/14/2010
    The SBEM might a suitable marker for molecular detection of ITCs in BM in breast cancer patients. Analysis of prognostic value for SBEM mRNA-based assay should take into account the heterogeneity and different molecular subtypes of breast cancer.

    Diagnostic accuracy of small breast epithelial mucin mRNA as a marker for bone marrow micrometastasis in breast cancer: a pilot study.
    Valladares-Ayerbes M, Iglesias-Díaz P, Díaz-Prado S, Ayude D, Medina V, Haz M, Reboredo M, Antolín S, Calvo L, Antón-Aparicio LM.

    01/21/2010
    results demonstrate that SBEM mRNA may be an important marker for targeting breast cancer micrometastasis

    In silico and in vitro analysis of small breast epithelial mucin as a marker for bone marrow micrometastasis in breast cancer.
    Ayerbes MV, Díaz-Prado S, Ayude D, Campelo RG, Iglesias P, Haz M, Medina V, Gallegos I, Quindós M, Aparicio LA.

    01/21/2010
    SBEM may identify a unique subset of breast cancers with poor prognosis and have implications for therapeutic management.

    Expression of small breast epithelial mucin (SBEM) protein in tissue microarrays (TMAs) of primary invasive breast cancers.
    Skliris GP, Hubé F, Gheorghiu I, Mutawe MM, Penner C, Watson PH, Murphy LC, Leygue E, Myal Y., Free PMC Article

    01/21/2010
    octamer-binding transcription factors participate in the strong expression of SBEM gene in breast tissues

    Identification of an octamer-binding site controlling the activity of the small breast epithelial mucin gene promoter.
    Hubé F, Chooniedass-Kothari S, Hamedani MK, Miksicek RJ, Leygue E, Myal Y.

    01/21/2010
    identification as possible new breast tumor biomarker

    Human small breast epithelial mucin: the promise of a new breast tumor biomarker.
    Hubé F, Mutawe M, Leygue E, Myal Y.

    01/21/2010
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