Sphingosine Kinase 2 Regulates Aryl Hydrocarbon Receptor Nuclear Translocation and Target Gene Activation. | Sphingosine Kinase 2 Regulates Aryl Hydrocarbon Receptor Nuclear Translocation and Target Gene Activation. Yokoyama S, Koo I, Aibara D, Tian Y, Murray IA, Collins SL, Coslo DM, Kono M, Peters JM, Proia RL, Gonzalez FJ, Perdew GH, Patterson AD., Free PMC Article | 11/5/2024 |
MerTK[+] macrophages promote melanoma progression and immunotherapy resistance through AhR-ALKAL1 activation. | MerTK(+) macrophages promote melanoma progression and immunotherapy resistance through AhR-ALKAL1 activation. Wu N, Li J, Li L, Yang L, Dong L, Shen C, Sha S, Fu Y, Dong E, Zheng F, Tan Z, Tao J., Free PMC Article | 10/10/2024 |
Involvement of Aryl Hydrocarbon Receptor in Longevity and Healthspan: Insights from Humans, Mice, and C. elegans. | Involvement of Aryl Hydrocarbon Receptor in Longevity and Healthspan: Insights from Humans, Mice, and C. elegans. Serna E, Verdú D, Valls A, Belenguer-Varea Á, Tarazona-Santabalbina FJ, Borrás C, Viña J., Free PMC Article | 10/4/2024 |
Aryl Hydrocarbon Receptor Activation in Pulmonary Alveolar Epithelial Cells Limits Inflammation and Preserves Lung Epithelial Cell Integrity. | Aryl Hydrocarbon Receptor Activation in Pulmonary Alveolar Epithelial Cells Limits Inflammation and Preserves Lung Epithelial Cell Integrity. Zimmerman E, Sturrock A, Reilly CA, Burrell-Gerbers KL, Warren K, Mir-Kasimov M, Zhang MA, Pierce MS, Helms MN, Paine R 3rd., Free PMC Article | 09/30/2024 |
Aryl Hydrocarbon Receptor Activation Limits the Fatty Acid Synthesis and Subsequent "miR-193a-3p-HDAC3-FASN" Signals to Alleviate Intestinal Fibrosis. | Aryl Hydrocarbon Receptor Activation Limits the Fatty Acid Synthesis and Subsequent "miR-193a-3p-HDAC3-FASN" Signals to Alleviate Intestinal Fibrosis. Wu X, Miao X, Xue X, Qiao S, Dai Y, Wei Z. | 09/16/2024 |
Aryl Hydrocarbon Receptor Knockout Accelerates PanIN Formation and Fibro-Inflammation in a Mutant Kras -Driven Pancreatic Cancer Model. | Aryl Hydrocarbon Receptor Knockout Accelerates PanIN Formation and Fibro-Inflammation in a Mutant Kras -Driven Pancreatic Cancer Model. Walcheck MT, Schwartz PB, Carrillo ND, Matkowskyj KA, Nukaya M, Bradfield CA, Ronnekleiv-Kelly SM., | 08/21/2024 |
Activation of aryl hydrocarbon receptor (AhR) alleviates depressive-like behaviors in LPS-induced mice. | Activation of aryl hydrocarbon receptor (AhR) alleviates depressive-like behaviors in LPS-induced mice. Wang MY, Li JM, Wu YL, Zhang Y, Hu T, Su WJ, Feng JF, Jiang CL. | 07/9/2024 |
Phosphorylation of aryl hydrocarbon receptor interacting protein by TBK1 negatively regulates IRF7 and the type I interferon response. | Phosphorylation of aryl hydrocarbon receptor interacting protein by TBK1 negatively regulates IRF7 and the type I interferon response. Kazzaz SA, Shaikh KA, White J, Zhou Q, Powell WH, Harhaj EW., Free PMC Article | 07/1/2024 |
Aryl hydrocarbon receptor activation alters immune cell populations in the lung and bone marrow during coronavirus infection. | Aryl hydrocarbon receptor activation alters immune cell populations in the lung and bone marrow during coronavirus infection. Healey AM, Fenner KN, O'Dell CT, Lawrence BP., | 05/24/2024 |
Tumor formation at ileocecal junction associated with interleukin-1beta upregulation in aryl hydrocarbon receptor-deficient mouse. | Tumor formation at ileocecal junction associated with interleukin-1β upregulation in aryl hydrocarbon receptor-deficient mouse. Ikuta T, Kanda H. | 05/22/2024 |
Silencing of aryl hydrocarbon receptor repressor restrains Th17 cell immunity in autoimmune hepatitis. | Silencing of aryl hydrocarbon receptor repressor restrains Th17 cell immunity in autoimmune hepatitis. Gao L, Zhang W, Zhang L, Gromova B, Chen G, Csizmadia E, Cagle C, Nastasio S, Ma Y, Bonder A, Patwardhan V, Robson SC, Jiang S, Longhi MS., | 04/3/2024 |
Indoxyl sulphate-initiated activation of cardiac fibroblasts is modulated by aryl hydrocarbon receptor and nuclear factor-erythroid-2-related factor 2. | Indoxyl sulphate-initiated activation of cardiac fibroblasts is modulated by aryl hydrocarbon receptor and nuclear factor-erythroid-2-related factor 2. Barisione C, Verzola D, Garibaldi S, Altieri P, Furfaro AL, Nitti M, Pratesi G, Palombo D, Ameri P., Free PMC Article | 03/22/2024 |
The aryl hydrocarbon receptor in beta-cells mediates the effects of TCDD on glucose homeostasis in mice. | The aryl hydrocarbon receptor in β-cells mediates the effects of TCDD on glucose homeostasis in mice. Hoyeck MP, Angela Ching ME, Basu L, van Allen K, Palaniyandi J, Perera I, Poleo-Giordani E, Hanson AA, Ghorbani P, Fullerton MD, Bruin JE., Free PMC Article | 03/11/2024 |
Immune cell-intrinsic Ah receptor facilitates the expression of antimicrobial REG3G in the small intestine. | Immune cell-intrinsic Ah receptor facilitates the expression of antimicrobial REG3G in the small intestine. Chakraborty D, Coslo DM, Murray IA, Vijay A, Patterson AD, Perdew GH. | 02/21/2024 |
Nuclear localization of STING1 competes with canonical signaling to activate AHR for commensal and intestinal homeostasis. | Nuclear localization of STING1 competes with canonical signaling to activate AHR for commensal and intestinal homeostasis. Zhang R, Yu C, Zeh HJ, Wang H, Kroemer G, Klionsky DJ, Billiar TR, Kang R, Tang D., | 12/21/2023 |
AhR and CYP1B1 Control Oxygen Effects on Bone Marrow Progenitor Cells: The Enrichment of Multiple Olfactory Receptors as Potential Microbiome Sensors. | AhR and CYP1B1 Control Oxygen Effects on Bone Marrow Progenitor Cells: The Enrichment of Multiple Olfactory Receptors as Potential Microbiome Sensors. Larsen MC, Rondelli CM, Almeldin A, Song YS, N'Jai A, Alexander DL, Forsberg EC, Sheibani N, Jefcoate CR., Free PMC Article | 12/20/2023 |
Involvement of the aryl hydrocarbon receptor (AhR) in the mechanism of action of elastin-derived peptide (VGVAPG) and its impact on neurosteroidogenesis. | Involvement of the aryl hydrocarbon receptor (AhR) in the mechanism of action of elastin-derived peptide (VGVAPG) and its impact on neurosteroidogenesis. Szychowski KA, Skóra B. | 12/15/2023 |
Deletion of the aryl hydrocarbon receptor in endothelial cells improves ischemic angiogenesis in chronic kidney disease. | Deletion of the aryl hydrocarbon receptor in endothelial cells improves ischemic angiogenesis in chronic kidney disease. Palzkill VR, Tan J, Yang Q, Morcos J, Laitano O, Ryan TE., | 12/6/2023 |
Activation of the aryl hydrocarbon receptor inhibits neuropilin-1 upregulation on IL-2-responding CD4[+] T cells. | Activation of the aryl hydrocarbon receptor inhibits neuropilin-1 upregulation on IL-2-responding CD4(+) T cells. Sandoval S, Malany K, Thongphanh K, Martinez CA, Goodson ML, Souza FDC, Lin LW, Sweeney N, Pennington J, Lein PJ, Kerkvliet NI, Ehrlich AK., Free PMC Article | 12/5/2023 |
Tumor cell-released kynurenine biases MEP differentiation into megakaryocytes in individuals with cancer by activating AhR-RUNX1. | Tumor cell-released kynurenine biases MEP differentiation into megakaryocytes in individuals with cancer by activating AhR-RUNX1. Zhou L, Wu D, Zhou Y, Wang D, Fu H, Huang Q, Qin G, Chen J, Lv J, Lai S, Zhang H, Tang K, Ma J, Fiskesund R, Zhang Y, Zhang X, Huang B., Free PMC Article | 11/30/2023 |
Commensal bacteria signal through TLR5 and AhR to improve barrier integrity and prevent allergic responses to food. | Commensal bacteria signal through TLR5 and AhR to improve barrier integrity and prevent allergic responses to food. Kemter AM, Patry RT, Arnold J, Hesser LA, Campbell E, Ionescu E, Mimee M, Wang S, Nagler CR., Free PMC Article | 11/8/2023 |
Aryl hydrocarbon receptor attenuates cholestatic liver injury by regulating bile acid metabolism. | Aryl hydrocarbon receptor attenuates cholestatic liver injury by regulating bile acid metabolism. Han Q, Yan X, Wang L, Zhang N, Zhang W, Li H, Chen W, You H, Yang A. | 11/2/2023 |
Endothelial AHR activity prevents lung barrier disruption in viral infection. | Endothelial AHR activity prevents lung barrier disruption in viral infection. Major J, Crotta S, Finsterbusch K, Chakravarty P, Shah K, Frederico B, D'Antuono R, Green M, Meader L, Suarez-Bonnet A, Priestnall S, Stockinger B, Wack A., Free PMC Article | 10/2/2023 |
Ligand Activation of the Aryl Hydrocarbon Receptor Upregulates Epidermal Uridine Diphosphate Glucose Ceramide Glucosyltransferase and Glucosylceramides. | Ligand Activation of the Aryl Hydrocarbon Receptor Upregulates Epidermal Uridine Diphosphate Glucose Ceramide Glucosyltransferase and Glucosylceramides. Sutter CH, Azim S, Wang A, Bhuju J, Simpson AS, Uberoi A, Grice EA, Sutter TR., Free PMC Article | 09/25/2023 |
The aryl hydrocarbon receptor directs the differentiation of murine progenitor blastomeres. | The aryl hydrocarbon receptor directs the differentiation of murine progenitor blastomeres. Ko CI, Biesiada J, Zablon HA, Zhang X, Medvedovic M, Puga A., Free PMC Article | 08/16/2023 |