The cell adhesion protein dystroglycan affects the structural remodeling of dendritic spines. | The cell adhesion protein dystroglycan affects the structural remodeling of dendritic spines. Figiel I, Bączyńska E, Wójtowicz T, Magnowska M, Buszka A, Bijata M, Włodarczyk J., Free PMC Article | 03/19/2022 |
MiR-132 down-regulates high glucose-induced beta-dystroglycan degradation through Matrix Metalloproteinases-9 up-regulation in primary neurons. | MiR-132 down-regulates high glucose-induced β-dystroglycan degradation through Matrix Metalloproteinases-9 up-regulation in primary neurons. Dou Y, Tan Y, Yu T, Ma X, Zhou Y, Zhao Y, Zhao Y, Liu X., Free PMC Article | 02/19/2022 |
The alteration of DG expression could regulate that of AQP4 expression after Traumatic Brain Injury . | Lost Polarization of Aquaporin4 and Dystroglycan in the Core Lesion after Traumatic Brain Injury Suggests Functional Divergence in Evolution. Liu H, Qiu Gp, Zhuo F, Yu Wh, Sun Sq, Li Fh, Yang M., Free PMC Article | 09/3/2016 |
a role for beta-dystroglycan in targeting and stabilizing AQP4 channel in astrocytic cells, which may be critical for water homeostasis in brain. | Loss of AQP4 polarized localization with loss of β-dystroglycan immunoreactivity may induce brain edema following intracerebral hemorrhage. Qiu GP, Xu J, Zhuo F, Sun SQ, Liu H, Yang M, Huang J, Lu WT, Huang SQ. | 08/29/2015 |
Dystroglycan binding to alpha-neurexin competes with neurexophilin-1 and neuroligin in the brain. | Dystroglycan binding to α-neurexin competes with neurexophilin-1 and neuroligin in the brain. Reissner C, Stahn J, Breuer D, Klose M, Pohlentz G, Mormann M, Missler M., Free PMC Article | 12/20/2014 |
These results suggest that dystroglycan-Lm interactions influence oligodendroglial process dynamics and therefore may regulate the myelination capacity of individual oligodendroglia. | Dystroglycan promotes filopodial formation and process branching in differentiating oligodendroglia. Eyermann C, Czaplinski K, Colognato H. | 06/2/2012 |
Alterations in the immunoreactivities and expressions of beta-dystroglycan, utrophin, and laminin seem to correlate with angiogenesis rather than BBB disruption during cerebral hypoperfusion. | Dynamics of dystroglycan complex proteins and laminin changes due to angiogenesis in rat cerebral hypoperfusion. Wappler EA, Adorján I, Gál A, Galgóczy P, Bindics K, Nagy Z. | 07/30/2011 |
we identified and examined a connection between dystroglycan and the ability of insulin-like growth factor-1 (IGF-1) to promote oligodendrocyte differentiation | Dystroglycan modulates the ability of insulin-like growth factor-1 to promote oligodendrocyte differentiation. Galvin J, Eyermann C, Colognato H., Free PMC Article | 01/29/2011 |
Findings demonstrate the interdependence between laminin binding to dystroglycan and GM1-containing lipid raft reorganization and provide novel insight into the dystrophin complex regulation of AQP4 polarization in astrocytes. | Interdependence of laminin-mediated clustering of lipid rafts and the dystrophin complex in astrocytes. Noël G, Tham DK, Moukhles H., Free PMC Article | 01/21/2010 |
These results suggest that exposure to cyclic stretch activates the metabolic sensing pathway AMPK in the lung epithelium and supports a novel role for dystroglycan in this mechanotransduction. | Stretch-induced activation of AMP kinase in the lung requires dystroglycan. Budinger GR, Urich D, DeBiase PJ, Chiarella SE, Burgess ZO, Baker CM, Soberanes S, Mutlu GM, Jones JC., Free PMC Article | 01/21/2010 |
astrocytes differentiated from dag1 fail to extend process and cell polarization is disrupted partially | Integrins and dystroglycan regulate astrocyte wound healing: the integrin beta1 subunit is necessary for process extension and orienting the microtubular network. Peng H, Shah W, Holland P, Carbonetto S. | 01/21/2010 |
functional damage of the dystroglycan complex is linked with structural changes in the glomerular basement membrane. | Podocyte flattening and disorder of glomerular basement membrane are associated with splitting of dystroglycan-matrix interaction. Kojima K, Davidovits A, Poczewski H, Langer B, Uchida S, Nagy-Bojarski K, Hovorka A, Sedivy R, Kerjaschki D. | 01/21/2010 |
Study reports that the myelinating glia of the CNS, oligodendrocytes, express and use dystroglycan receptors to regulate myelin formation. | Identification of dystroglycan as a second laminin receptor in oligodendrocytes, with a role in myelination. Colognato H, Galvin J, Wang Z, Relucio J, Nguyen T, Harrison D, Yurchenco PD, Ffrench-Constant C. | 01/21/2010 |
Dystroglycan regulates endocytosis possibly as a result of its interaction with dynamin. | Evidence that dystroglycan is associated with dynamin and regulates endocytosis. Zhan Y, Tremblay MR, Melian N, Carbonetto S. | 01/21/2010 |
Inhibition of dystroglycan caused a decrease in the ability of laminin-1 to stimulate cell migration. Dystroglycan function does not influence laminin-1-dependent increase in process dynamism and direction-changing activity. | Dystroglycan is involved in laminin-1-stimulated motility of Müller glial cells: combined velocity and directionality analysis. Méhes E, Czirók A, Hegedüs B, Szabó B, Vicsek T, Satz J, Campbell K, Jancsik V. | 01/21/2010 |