| COUP-TFII plays a role in cAMP-induced Schwann cell differentiation and in vitro myelination by up-regulating Krox20. | COUP-TFII plays a role in cAMP-induced Schwann cell differentiation and in vitro myelination by up-regulating Krox20.
Han SH, Kim YH, Park SJ, Cho JG, Shin YK, Hong YB, Yun J, Han JY, Park HT, Park JI. | 06/2/2023 |
| Nr2f2 mutation in the hinge region attenuates salt-sensitive hypertension | Mutation within the hinge region of the transcription factor Nr2f2 attenuates salt-sensitive hypertension.
Kumarasamy S, Waghulde H, Gopalakrishnan K, Mell B, Morgan E, Joe B., Free PMC Article | 03/19/2016 |
| These data demonstrate that Nr2f2 is a direct target of POU4F3 in vitro and that this regulatory relationship may be relevant to hair cell development and survival. | Regulation of the orphan nuclear receptor Nr2f2 by the DFNA15 deafness gene Pou4f3.
Tornari C, Towers ER, Gale JE, Dawson SJ., Free PMC Article | 11/28/2015 |
| Apoc3 expression is regulated by HNF4a and COUP-TFII but not by retinoic acid in rat hepatocytes. | The expression of Apoc3 mRNA is regulated by HNF4α and COUP-TFII, but not acute retinoid treatments, in primary rat hepatocytes and hepatoma cells.
Howell M, Li R, Zhang R, Li Y, Chen W, Chen G. | 09/27/2014 |
| oxygen-glucose deprivation could induce the expressions of VEGF, Ang-1, and Ang-2, with the expression of Shh signaling components increased. | Sonic hedgehog (Shh) regulates the expression of angiogenic growth factors in oxygen-glucose-deprived astrocytes by mediating the nuclear receptor NR2F2.
Li Y, Xia Y, Wang Y, Mao L, Gao Y, He Q, Huang M, Chen S, Hu B. | 11/16/2013 |
| Upregulation of COUP-II gene expression in the PPF may contribute to the diaphragmatic defect in the nitrofen congenital diaphragmatic hernia rat model by inhibiting the RSP. | COUP-TFII gene expression is upregulated in embryonic pleuroperitoneal folds in the nitrofen-induced congenital diaphragmatic hernia rat model.
Dingemann J, Doi T, Ruttenstock EM, Gosemann JH, Puri P. | 07/28/2012 |
| Cloning of rat pituitary COUP-TFII and EAR-2 genes, demonstrated that they are specifically expressed in lactotropes, and strongly suggested that they may play a role in modulating prolactin (PRL) gene expression during pregnancy. | Cloning, expression and regulation of chicken ovalbumin upstream promoter transcription factors (COUP-TFII and EAR-2) in the rat anterior pituitary gland.
Raccurt M, Smallwood S, Mertani HC, Devost D, Abbaci K, Boutin JM, Morel G. | 07/29/2011 |
| Characterization of COUP-TFII-expressing neurons suggests that this developmentally important transcription factor plays cell type-specific role(s) in the adult hippocampus. | Expression of COUP-TFII nuclear receptor in restricted GABAergic neuronal populations in the adult rat hippocampus.
Fuentealba P, Klausberger T, Karayannis T, Suen WY, Huck J, Tomioka R, Rockland K, Capogna M, Studer M, Morales M, Somogyi P., Free PMC Article | 03/8/2010 |
| up-regulation of COUP-TFII gene expression during the stage of branching lung morphogenesis may cause pulmonary hypoplasia by repressing the retinoid signaling pathway | Up-regulation of COUP-TFII gene expression in the nitrofen-induced hypoplastic lung.
Doi T, Sugimoto K, Puri P. | 01/21/2010 |
| COUP-TFII gene expression is repressed by secreted insulin in response to glucose through Foxo1 signaling and this negative glucose effect involves ChREBP expression. | The transcription factor COUP-TFII is negatively regulated by insulin and glucose via Foxo1- and ChREBP-controlled pathways.
Perilhou A, Tourrel-Cuzin C, Kharroubi I, Henique C, Fauveau V, Kitamura T, Magnan C, Postic C, Prip-Buus C, Vasseur-Cognet M., Free PMC Article | 01/21/2010 |
| ARP-1/COUP-TFII acts as both a transcriptional repressor of microsomal triglyceride transfer protein and as a transcription activator of CYP7A1. | ARP-1/COUP-TF II determines hepatoma phenotype by acting as both a transcriptional repressor of microsomal triglyceride transfer protein and an inducer of CYP7A1.
Kang S, Spann NJ, Hui TY, Davis RA. | 01/21/2010 |