| Tailored modulation of S100A1 and RASSF8 expression by butanediamide augments healing of rotator cuff tears. | Tailored modulation of S100A1 and RASSF8 expression by butanediamide augments healing of rotator cuff tears.
Lin Y, Guo R, R G, Xu B., Free PMC Article | 08/22/2023 |
| CircCERS6 Suppresses the Development of Epithelial Ovarian Cancer Through Mediating miR-630/RASSF8. | CircCERS6 Suppresses the Development of Epithelial Ovarian Cancer Through Mediating miR-630/RASSF8.
Li X, Jiang X, Lu J, Lin Y, Jiang L, Li Y, Wan F, Wang C. | 11/5/2022 |
| RASSF8-AS1 displays low expression in colorectal cancer and up-regulates RASSF8 to suppress cell invasion and migration. | RASSF8-AS1 displays low expression in colorectal cancer and up-regulates RASSF8 to suppress cell invasion and migration.
Zhang X, Sun P, Yang W, Li S, Jia H, Wang W, Jiang S, Wang L, Liu X, Liang L, Zi W. | 10/29/2022 |
| data provide evidence that E4BP4 attenuates RASSF8-mediated anti-proliferation and apoptosis, shedding mechanistic insights into RASSF8 down-regulation in breast cancers. | E4BP4/NFIL3 modulates the epigenetically repressed RAS effector RASSF8 function through histone methyltransferases.
Karthik IP, Desai P, Sukumar S, Dimitrijevic A, Rajalingam K, Mahalingam S., Free PMC Article | 12/22/2018 |
| MiR-505 mediated MTX resistance, propagation, cell cycle and metastasis by targeting RASSF8 in colorectal cancer | MiR-505 mediates methotrexate resistance in colorectal cancer by targeting RASSF8.
Chen Y, Bian L, Zhang Y. | 10/27/2018 |
| The miR-224 played an oncogenic role in the proliferation of NSCLC by direct targeting RASSF8. | The miR-224 promotes non-small cell lung cancer cell proliferation by directly targeting RASSF8.
Wang L, Liu W, Zhang YP, Huang XR. | 08/11/2018 |
| RASSF8 knockdown by specific RNAi showed similar effects in cervical cancer cells transfected with miR-224 mimic. Our findings suggest that miR-224 directly targets RASSF8 and thereby acts as a tumor promoter in cervical cancer progression | Over-Expressed miR-224 Promotes the Progression of Cervical Cancer via Targeting RASSF8.
Huang Y, Li Y, Wang FF, Lv W, Xie X, Cheng X., Free PMC Article | 08/5/2017 |
| These results indicate that hypoxia-inducible miR-224 promotes gastric cancer cell growth, migration and invasion by downregulating RASSF8 and acts as an oncogene, implying that inhibition of miR-224 may have potential as a therapeutic target for patients with hypoxic gastric tumors. | Hypoxia-inducible microRNA-224 promotes the cell growth, migration and invasion by directly targeting RASSF8 in gastric cancer.
He C, Wang L, Zhang J, Xu H., Free PMC Article | 07/29/2017 |
| RASSF8 acts as a tumor suppressor in squamous cell carcinoma | RASSF8 downregulation promotes lymphangiogenesis and metastasis in esophageal squamous cell carcinoma.
Zhang L, Wang JH, Liang RX, Huang ST, Xu J, Yuan LJ, Huang L, Zhou Y, Yu XJ, Wu SY, Luo RZ, Yun JP, Jia WH, Zheng M., Free PMC Article | 08/13/2016 |
| RASSF8 plays a significant role in suppressing the progression of cutaneous melanoma. | RASSF8 regulates progression of cutaneous melanoma through nuclear factor-κb.
Wang J, Hua W, Huang SK, Fan K, Takeshima L, Mao Y, Hoon DS., Free PMC Article | 08/6/2016 |
| RASSF8 as a tumor suppressor gene that is essential for maintaining AJs function in epithelial cells and have a role in epithelial cell migration. | The RASSF8 candidate tumor suppressor inhibits cell growth and regulates the Wnt and NF-kappaB signaling pathways.
Lock FE, Underhill-Day N, Dunwell T, Matallanas D, Cooper W, Hesson L, Recino A, Ward A, Pavlova T, Zabarovsky E, Grant MM, Maher ER, Chalmers AD, Kolch W, Latif F. | 08/23/2010 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | Common polymorphisms in D12S1034 flanking genes RASSF8 and BHLHB3 are not associated with lung adenocarcinoma risk.
Falvella FS, Spinola M, Manenti G, Conti B, Pastorino U, Skaug V, Haugen A, Dragani TA. | 03/13/2008 |
| Expression of RASSF8 protein by transfected lung cancer cells led to inhibition of anchorage-independent growth in soft agar in A549 cells and reduction of clonogenic activity in NCI-H520 cells | Identification of RASSF8 as a candidate lung tumor suppressor gene.
Falvella FS, Manenti G, Spinola M, Pignatiello C, Conti B, Pastorino U, Dragani TA. | 01/21/2010 |