| A severe neurocognitive phenotype caused by biallelic CHD3 variants in two siblings. | A severe neurocognitive phenotype caused by biallelic CHD3 variants in two siblings.
Goldfarb Yaacobi R, Sukenik Halevy R. | 03/11/2024 |
| Snijders Blok-Campeau Syndrome: Description of 20 Additional Individuals with Variants in CHD3 and Literature Review. | Snijders Blok-Campeau Syndrome: Description of 20 Additional Individuals with Variants in CHD3 and Literature Review.
Pascual P, Tenorio-Castano J, Mignot C, Afenjar A, Arias P, Gallego-Zazo N, Parra A, Miranda L, Cazalla M, Silván C, Heron D, Keren B, Popa I, Palomares M, Rikeros E, Ramos FJ, Almoguera B, Ayuso C, Swafiri ST, Barbero AIS, Srinivasan VM, Gowda VK, Morleo M, Nigro V, D'Arrigo S, Ciaccio C, Martin Mesa C, Paumard B, Guillen G, Anton ATS, Jimenez MD, Seidel V, Suárez J, Cormier-Daire V, Consortium TS, Nevado J, Lapunzina P., Free PMC Article | 10/6/2023 |
| Inherited variants in CHD3 show variable expressivity in Snijders Blok-Campeau syndrome. | Inherited variants in CHD3 show variable expressivity in Snijders Blok-Campeau syndrome.
van der Spek J, den Hoed J, Snijders Blok L, Dingemans AJM, Schijven D, Nellaker C, Venselaar H, Astuti GDN, Barakat TS, Bebin EM, Beck-Wödl S, Beunders G, Brown NJ, Brunet T, Brunner HG, Campeau PM, Čuturilo G, Gilissen C, Haack TB, Hüning I, Husain RA, Kamien B, Lim SC, Lovrecic L, Magg J, Maver A, Miranda V, Monteil DC, Ockeloen CW, Pais LS, Plaiasu V, Raiti L, Richmond C, Rieß A, Schwaibold EMC, Simon MEH, Spranger S, Tan TY, Thompson ML, de Vries BBA, Wilkins EJ, Willemsen MH, Francks C, Vissers LELM, Fisher SE, Kleefstra T. | 06/11/2022 |
| Sequence and functional differences in the ATPase domains of CHD3 and SNF2H promise potential for selective regulability and drugability. | Sequence and functional differences in the ATPase domains of CHD3 and SNF2H promise potential for selective regulability and drugability.
Hoffmeister H, Fuchs A, Komives E, Groebner-Ferreira R, Strobl L, Nazet J, Heizinger L, Merkl R, Dove S, Längst G. | 08/7/2021 |
| A second cohort of CHD3 patients expands the molecular mechanisms known to cause Snijders Blok-Campeau syndrome. | A second cohort of CHD3 patients expands the molecular mechanisms known to cause Snijders Blok-Campeau syndrome.
Drivas TG, Li D, Nair D, Alaimo JT, Alders M, Altmüller J, Barakat TS, Bebin EM, Bertsch NL, Blackburn PR, Blesson A, Bouman AM, Brockmann K, Brunelle P, Burmeister M, Cooper GM, Denecke J, Dieux-Coëslier A, Dubbs H, Ferrer A, Gal D, Bartik LE, Gunderson LB, Hasadsri L, Jain M, Karimov C, Keena B, Klee EW, Kloth K, Lace B, Macchiaiolo M, Marcadier JL, Milunsky JM, Napier MP, Ortiz-Gonzalez XR, Pichurin PN, Pinner J, Powis Z, Prasad C, Radio FC, Rasmussen KJ, Renaud DL, Rush ET, Saunders C, Selcen D, Seman AR, Shinde DN, Smith ED, Smol T, Snijders Blok L, Stoler JM, Tang S, Tartaglia M, Thompson ML, van de Kamp JM, Wang J, Weise D, Weiss K, Woitschach R, Wollnik B, Yan H, Zackai EH, Zampino G, Campeau P, Bhoj E., Free PMC Article | 06/12/2021 |
| A Multi-Trait Approach Identified Genetic Variants Including a Rare Mutation in RGS3 with Impact on Abnormalities of Cardiac Structure/Function. | A Multi-Trait Approach Identified Genetic Variants Including a Rare Mutation in RGS3 with Impact on Abnormalities of Cardiac Structure/Function.
Yazdani A, Yazdani A, Méndez Giráldez R, Aguilar D, Sartore L., Free PMC Article | 10/24/2020 |
| It has been proposed that the functional link between chromatin remodeling by CHD3 and deSUMOylation by SENP1 provides another level of control of gene expression. | The SUMO protease SENP1 and the chromatin remodeler CHD3 interact and jointly affect chromatin accessibility and gene expression.
Rodríguez-Castañeda F, Lemma RB, Cuervo I, Bengtsen M, Moen LM, Ledsaak M, Eskeland R, Gabrielsen OS., Free PMC Article | 03/9/2019 |
| The tandem PHD fingers of CHD3 bind histone H3 tails. | Covalent Modifications of Histone H3K9 Promote Binding of CHD3.
Tencer AH, Cox KL, Di L, Bridgers JB, Lyu J, Wang X, Sims JK, Weaver TM, Allen HF, Zhang Y, Gatchalian J, Darcy MA, Gibson MD, Ikebe J, Li W, Wade PA, Hayes JJ, Strahl BD, Kono H, Poirier MG, Musselman CA, Kutateladze TG., Free PMC Article | 06/16/2018 |
| CHD3 and CHD4 exhibit distinct nuclear localization patterns in unperturbed cells, revealing a subset of specific target genes. | CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.
Hoffmeister H, Fuchs A, Erdel F, Pinz S, Gröbner-Ferreira R, Bruckmann A, Deutzmann R, Schwartz U, Maldonado R, Huber C, Dendorfer AS, Rippe K, Längst G., Free PMC Article | 11/11/2017 |
| Mutations in CHD3 gene is associated with cutaneous T cell lymphoma and Sezary syndrome. | The mutational landscape of cutaneous T cell lymphoma and Sézary syndrome.
da Silva Almeida AC, Abate F, Khiabanian H, Martinez-Escala E, Guitart J, Tensen CP, Vermeer MH, Rabadan R, Ferrando A, Palomero T., Free PMC Article | 06/28/2016 |
| CHD3 was confirmed to interact with NES1 in NS2, and a disruption to this interaction by mutation in NES1 significantly delayed viral vRNPs export and viral propagation. | CHD3 facilitates vRNP nuclear export by interacting with NES1 of influenza A virus NS2.
Hu Y, Liu X, Zhang A, Zhou H, Liu Z, Chen H, Jin M., Free PMC Article | 04/11/2015 |
| CHD3.1 and ACF1-SNF2H display counteractive activities but similar histone affinities. | Opposing ISWI- and CHD-class chromatin remodeling activities orchestrate heterochromatic DNA repair.
Klement K, Luijsterburg MS, Pinder JB, Cena CS, Del Nero V, Wintersinger CM, Dellaire G, van Attikum H, Goodarzi AA., Free PMC Article | 02/28/2015 |
| In this study, the chromatin remodeler chromodomain helicase DNA binding (CHD3) protein is identified as an important component of the initial repression of the herpesvirus genome. | Epigenetic repression of herpes simplex virus infection by the nucleosome remodeler CHD3.
Arbuckle JH, Kristie TM., Free PMC Article | 08/30/2014 |
| UV radiation regulates Mi-2 through protein translation and stability | UV radiation regulates Mi-2 through protein translation and stability.
Burd CJ, Kinyamu HK, Miller FW, Archer TK., Free PMC Article | 01/21/2010 |
| Pericentrin forms complexes with CHD3 and CHD4, but a distinct CHD3-pericentrin complex is required for centrosomal anchoring of pericentrin/gamma-tubulin and for centrosome integrity. | Chromatin remodeling proteins interact with pericentrin to regulate centrosome integrity.
Sillibourne JE, Delaval B, Redick S, Sinha M, Doxsey SJ., Free PMC Article | 01/21/2010 |
| effect of progressive C-terminal deletions of CHD3, which indicated that sequences required for repression of PS1 lie between amino acids 1955 and 1877 | The C-terminal region of CHD3/ZFH interacts with the CIDD region of the Ets transcription factor ERM and represses transcription of the human presenilin 1 gene.
Pastorcic M, Das HK. | 01/21/2010 |