| Clinical Significance of CD66b Expression in Non-Small Cell Lung Cancer. | Clinical Significance of CD66b Expression in Non-Small Cell Lung Cancer.
Kovaleva OV, Podlesnaya PA, Mochalnikova VV, Kushlinskii NE, Gratchev AN. | 05/23/2023 |
| CD66b(+) monocytes represent a proinflammatory myeloid subpopulation in cancer. | CD66b(+) monocytes represent a proinflammatory myeloid subpopulation in cancer.
Horzum U, Yoyen-Ermis D, Taskiran EZ, Yilmaz KB, Hamaloglu E, Karakoc D, Esendagli G., Free PMC Article | 02/2/2021 |
| High CEACAM8 expression is associated with metastases in breast carcinoma. | Co-expression of carcinoembryonic antigen-related cell adhesion molecule 6 and 8 inhibits proliferation and invasiveness of breast carcinoma cells.
Iwabuchi E, Miki Y, Onodera Y, Shibahara Y, Takagi K, Suzuki T, Ishida T, Sasano H. | 04/11/2020 |
| Increased CD66b positive tumor-infiltrating neutrophils (CD66b + TINs) was significantly associated with presence of metastasis, S stage, and nonseminomatous germ cell tumor diagnosis. | Prognostic value of CD66b positive tumor-infiltrating neutrophils in testicular germ cell tumor.
Yamada Y, Nakagawa T, Sugihara T, Horiuchi T, Yoshizaki U, Fujimura T, Fukuhara H, Urano T, Takayama K, Inoue S, Kume H, Homma Y., Free PMC Article | 09/23/2017 |
| a 7-gene signature was identified which correctly predicted the primary prefibrotic myelofibrosis group with a sensitivity of 100% and a specificity of 89%. The 7 genes included MPO, CEACAM8, CRISP3, MS4A3, CEACAM6, HEMGN, and MMP8 | A 7-Gene Signature Depicts the Biochemical Profile of Early Prefibrotic Myelofibrosis.
Skov V, Burton M, Thomassen M, Stauffer Larsen T, Riley CH, Brinch Madelung A, Kjær L, Bondo H, Stamp I, Ehinger M, Dahl-Sørensen R, Brochmann N, Nielsen K, Thiele J, Jensen MK, Weis Bjerrum O, Kruse TA, Hasselbalch HC., Free PMC Article | 07/29/2017 |
| Inhibition of C5aR1 leads to a significant reduction of CD66b and CD11b expression indicating a lower neutrophil activation status and block of granule exocytosis. | CD66b Overexpression and Loss of C5a Receptors as Surface Markers for Staphylococcus aureus-Induced Neutrophil Dysfunction.
Schmidt T, Brodesser A, Schnitzler N, Grüger T, Brandenburg K, Zinserling J, Zündorf J., Free PMC Article | 04/30/2016 |
| Data suggest ways in which carcinoembryonic antigen-related cell adhesion molecules CEACAM6 and CEACAM8 regulate the biological functions of one another. | Diverse oligomeric states of CEACAM IgV domains.
Bonsor DA, Günther S, Beadenkopf R, Beckett D, Sundberg EJ., Free PMC Article | 03/19/2016 |
| CEACAM8 interacts with CEACAM1 inhibiting TLR2-triggered immune responses | Soluble CEACAM8 interacts with CEACAM1 inhibiting TLR2-triggered immune responses.
Singer BB, Opp L, Heinrich A, Schreiber F, Binding-Liermann R, Berrocal-Almanza LC, Heyl KA, Müller MM, Weimann A, Zweigner J, Slevogt H., Free PMC Article | 01/17/2015 |
| Granulocytes from type 2 diabetes patients display higher granulocyte cell surface expression of CD66b compared with values of healthy controls. | Fasting glucose level modulates cell surface expression of CD11b and CD66b in granulocytes and monocytes of patients with type 2 diabetes.
Horvath P, Oliver SR, Ganesan G, Zaldivar FP Jr, Radom-Aizik S, Galassetti PR., Free PMC Article | 07/12/2014 |
| The highly elevated gene expression of CEACAM6 and CEACAM8 in primary myelofibrosis can serve as molecular markers of myelofibrotic transformation. | High expression of carcinoembryonic antigen-related cell adhesion molecule (CEACAM) 6 and 8 in primary myelofibrosis.
Hasselbalch HC, Skov V, Larsen TS, Thomassen M, Riley CH, Jensen MK, Bjerrum OW, Kruse TA. | 11/26/2011 |
| Data show that desensitization of neutrophils to any two CEACAMs, 1, 3, 6, or 8, results in selective desensitization to those two CEACAMs, while the cells remain responsive to the other two neutrophil CEACAMs. | Interdependency of CEACAM-1, -3, -6, and -8 induced human neutrophil adhesion to endothelial cells.
Skubitz KM, Skubitz AP., Free PMC Article | 01/21/2010 |
| All the leukemic samples showed overexpression of CEACAM6 and 8 when compared with normal granulocytes. | High expression of CEACAM6 and CEACAM8 mRNA in acute lymphoblastic leukemias.
Lasa A, Serrano E, Carricondo M, Carnicer MJ, Brunet S, Badell I, Sierra J, Aventín A, Nomdedéu JF. | 01/21/2010 |
| CD66b molecules are involved in regulating adhesion and activation of eosinophils, possibly through their localization in lipid rafts and interaction with other cell surface molecules, such as CD11b. | CD66b regulates adhesion and activation of human eosinophils.
Yoon J, Terada A, Kita H. | 01/21/2010 |