| Pan-cancer mapping of single CD8[+] T cell profiles reveals a TCF1:CXCR6 axis regulating CD28 co-stimulation and anti-tumor immunity. | Pan-cancer mapping of single CD8(+) T cell profiles reveals a TCF1:CXCR6 axis regulating CD28 co-stimulation and anti-tumor immunity.
Tooley K, Jerby L, Escobar G, Krovi SH, Mangani D, Dandekar G, Cheng H, Madi A, Goldschmidt E, Lambden C, Krishnan RK, Rozenblatt-Rosen O, Regev A, Anderson AC., Free PMC Article | 08/16/2024 |
| MiR-625-5p is a potential therapeutic target in sepsis by regulating CXCL16/CXCR6 axis and endothelial barrier. | MiR-625-5p is a potential therapeutic target in sepsis by regulating CXCL16/CXCR6 axis and endothelial barrier.
Huang X, Fei Y, Qiu X, Qian T, Shang Q, Cui J, Song Y, Sheng S, Xiao W, Yu Q, Wang T, Wang X. | 08/5/2024 |
| rs71327024 Associated with COVID-19 Hospitalization Reduces CXCR6 Promoter Activity in Human CD4[+] T Cells via Disruption of c-Myb Binding. | rs71327024 Associated with COVID-19 Hospitalization Reduces CXCR6 Promoter Activity in Human CD4(+) T Cells via Disruption of c-Myb Binding.
Uvarova AN, Stasevich EM, Ustiugova AS, Mitkin NA, Zheremyan EA, Sheetikov SA, Zornikova KV, Bogolyubova AV, Rubtsov MA, Kulakovskiy IV, Kuprash DV, Korneev KV, Schwartz AM., Free PMC Article | 09/30/2023 |
| Association of 3p21.31 Locus (CXCR6 and LZTFL1) with COVID-19 Outcomes in Brazilian Hospitalyzed Subjects. | Association of 3p21.31 Locus (CXCR6 and LZTFL1) with COVID-19 Outcomes in Brazilian Hospitalyzed Subjects.
de Araújo JLF, Bonifácio VF, Batista LM, de Ávila RE, Aguiar RS, Bastos-Rodrigues L, de Souza RP. | 08/16/2023 |
| Clonally expanded, thyrotoxic effector CD8[+] T cells driven by IL-21 contribute to checkpoint inhibitor thyroiditis. | Clonally expanded, thyrotoxic effector CD8(+) T cells driven by IL-21 contribute to checkpoint inhibitor thyroiditis.
Lechner MG, Zhou Z, Hoang AT, Huang N, Ortega J, Scott LN, Chen HC, Patel AY, Yakhshi-Tafti R, Kim K, Hugo W, Famini P, Drakaki A, Ribas A, Angell TE, Su MA., Free PMC Article | 06/7/2023 |
| Platelet SR-PSOX/CXCL16-CXCR6 Axis Influences Thrombotic Propensity and Prognosis in Coronary Artery Disease. | Platelet SR-PSOX/CXCL16-CXCR6 Axis Influences Thrombotic Propensity and Prognosis in Coronary Artery Disease.
Guan T, Emschermann F, Schories C, Groga-Bada P, Martus P, Borst O, Gawaz M, Geisler T, Rath D, Chatterjee M., Free PMC Article | 10/22/2022 |
| CXCL16 Promotes Gastric Cancer Tumorigenesis via ADAM10-Dependent CXCL16/CXCR6 Axis and Activates Akt and MAPK Signaling Pathways. | CXCL16 Promotes Gastric Cancer Tumorigenesis via ADAM10-Dependent CXCL16/CXCR6 Axis and Activates Akt and MAPK Signaling Pathways.
Han J, Fu R, Chen C, Cheng X, Guo T, Huangfu L, Li X, Du H, Xing X, Ji J., Free PMC Article | 03/19/2022 |
| Phenotypic and Functional Plasticity of CXCR6(+) Peripheral Blood NK Cells. | Phenotypic and Functional Plasticity of CXCR6(+) Peripheral Blood NK Cells.
Angelo LS, Hogg GD, Abeynaike S, Bimler L, Vargas-Hernandez A, Paust S., Free PMC Article | 03/12/2022 |
| CXCL16/CXCR6 Axis in Adipocytes Differentiated from Human Adipose Derived Mesenchymal Stem Cells Regulates Macrophage Polarization. | CXCL16/CXCR6 Axis in Adipocytes Differentiated from Human Adipose Derived Mesenchymal Stem Cells Regulates Macrophage Polarization.
Lee SC, Lee YJ, Choi I, Kim M, Sung JS., Free PMC Article | 01/8/2022 |
| CXCR6 is required for antitumor efficacy of intratumoral CD8(+) T cell. | CXCR6 is required for antitumor efficacy of intratumoral CD8(+) T cell.
Wang B, Wang Y, Sun X, Deng G, Huang W, Wu X, Gu Y, Tian Z, Fan Z, Xu Q, Chen H, Sun Y., Free PMC Article | 01/8/2022 |
| Auto-aggressive CXCR6(+) CD8 T cells cause liver immune pathology in NASH. | Auto-aggressive CXCR6(+) CD8 T cells cause liver immune pathology in NASH.
Dudek M, Pfister D, Donakonda S, Filpe P, Schneider A, Laschinger M, Hartmann D, Hüser N, Meiser P, Bayerl F, Inverso D, Wigger J, Sebode M, Öllinger R, Rad R, Hegenbarth S, Anton M, Guillot A, Bowman A, Heide D, Müller F, Ramadori P, Leone V, Garcia-Caceres C, Gruber T, Seifert G, Kabat AM, Mallm JP, Reider S, Effenberger M, Roth S, Billeter AT, Müller-Stich B, Pearce EJ, Koch-Nolte F, Käser R, Tilg H, Thimme R, Boettler T, Tacke F, Dufour JF, Haller D, Murray PJ, Heeren R, Zehn D, Böttcher JP, Heikenwälder M, Knolle PA. | 12/11/2021 |
| Integrative approach identifies SLC6A20 and CXCR6 as putative causal genes for the COVID-19 GWAS signal in the 3p21.31 locus. | Integrative approach identifies SLC6A20 and CXCR6 as putative causal genes for the COVID-19 GWAS signal in the 3p21.31 locus.
Kasela S, Daniloski Z, Bollepalli S, Jordan TX, tenOever BR, Sanjana NE, Lappalainen T., Free PMC Article | 09/18/2021 |
| Association of CXCR6 with COVID-19 severity: delineating the host genetic factors in transcriptomic regulation. | Association of CXCR6 with COVID-19 severity: delineating the host genetic factors in transcriptomic regulation.
Dai Y, Wang J, Jeong HH, Chen W, Jia P, Zhao Z., Free PMC Article | 08/14/2021 |
| Long noncoding RNA JPX promotes gastric cancer progression by regulating CXCR6 and autophagy via inhibiting miR197. | Long non‑coding RNA JPX promotes gastric cancer progression by regulating CXCR6 and autophagy via inhibiting miR‑197.
Han X, Liu Z., Free PMC Article | 04/17/2021 |
| CXCL16/CXCR6 axis promotes bleomycin-induced fibrotic process in MRC-5 cells via the PI3K/AKT/FOXO3a pathway. | CXCL16/CXCR6 axis promotes bleomycin-induced fibrotic process in MRC-5 cells via the PI3K/AKT/FOXO3a pathway.
Ma Z, Yu R, Zhu Q, Sun L, Jian L, Wang X, Zhao J, Li C, Liu X. | 01/9/2021 |
| Higher CXCL16 exodomain is associated with aggressive ovarian cancer and promotes the disease by CXCR6 activation and MMP modulation. | Higher CXCL16 exodomain is associated with aggressive ovarian cancer and promotes the disease by CXCR6 activation and MMP modulation.
Mir H, Kaur G, Kapur N, Bae S, Lillard JW Jr, Singh S., Free PMC Article | 09/26/2020 |
| CXCR6(+) NK Cells in Human Fetal Liver and Spleen Possess Unique Phenotypic and Functional Capabilities. | CXCR6(+) NK Cells in Human Fetal Liver and Spleen Possess Unique Phenotypic and Functional Capabilities.
Angelo LS, Bimler LH, Nikzad R, Aviles-Padilla K, Paust S., Free PMC Article | 09/12/2020 |
| CXCL16/CXCR6-mediated adhesion of human peripheral blood mononuclear cells to inflamed endothelium. | CXCL16/CXCR6-mediated adhesion of human peripheral blood mononuclear cells to inflamed endothelium.
Linke B, Meyer Dos Santos S, Picard-Willems B, Keese M, Harder S, Geisslinger G, Scholich K. | 09/12/2020 |
| CXCL16/CXCR6 is involved in LPS-induced acute lung injury via P38 signalling. | CXCL16/CXCR6 is involved in LPS-induced acute lung injury via P38 signalling.
Tu GW, Ju MJ, Zheng YJ, Hao GW, Ma GG, Hou JY, Zhang XP, Luo Z, Lu LM., Free PMC Article | 08/15/2020 |
| we have identified a unique role for the chemokine receptor CXCR6 in directing the migration of TRM cells in the lung under steady-state conditions and maintaining the airway TRM cell pool. | CXCR6 regulates localization of tissue-resident memory CD8 T cells to the airways.
Wein AN, McMaster SR, Takamura S, Dunbar PR, Cartwright EK, Hayward SL, McManus DT, Shimaoka T, Ueha S, Tsukui T, Masumoto T, Kurachi M, Matsushima K, Kohlmeier JE., Free PMC Article | 06/20/2020 |
| Activation of CXCR6 resulted in increased GSK-3beta, NF-kappaB, ERK1/2 phosphorylation, and survivin expression, which reduce DTX response. | Prostate cancer cells hyper-activate CXCR6 signaling by cleaving CXCL16 to overcome effect of docetaxel.
Kapur N, Mir H, Sonpavde GP, Jain S, Bae S, Lillard JW Jr, Singh S., Free PMC Article | 04/11/2020 |
| CXCL16/CXCR6 signaling axis plays a functional role in metabolic syndrome endothelial dysfunction and abdominal aortic aneurysm formation. | Functional role of endothelial CXCL16/CXCR6-platelet-leucocyte axis in angiotensin II-associated metabolic disorders.
Collado A, Marques P, Escudero P, Rius C, Domingo E, Martinez-Hervás S, Real JT, Ascaso JF, Piqueras L, Sanz MJ. | 10/26/2019 |
| CXCL16/CXCR6 signaling acts directly on mouse glioma cells. | CXCL16/CXCR6 Axis Drives Microglia/Macrophages Phenotype in Physiological Conditions and Plays a Crucial Role in Glioma.
Lepore F, D'Alessandro G, Antonangeli F, Santoro A, Esposito V, Limatola C, Trettel F., Free PMC Article | 10/5/2019 |
| Activation of the CXCL16/CXCR6 Axis by TNF-alpha Contributes to Ectopic Endometrial Stromal Cells Migration and Invasion.. These findings indicate that the CXCL16/CXCR6 axis may contribute to the progression of endometriosis and could be served as a potential target for diagnosis and treatment. | Activation of the CXCL16/CXCR6 Axis by TNF-α Contributes to Ectopic Endometrial Stromal Cells Migration and Invasion.
Peng Y, Ma J, Lin J. | 04/20/2019 |
| IL-12 and IL-15 induce the expression of CXCR6 and CD49a on peripheral natural killer cells. | IL-12 and IL-15 induce the expression of CXCR6 and CD49a on peripheral natural killer cells.
Hydes T, Noll A, Salinas-Riester G, Abuhilal M, Armstrong T, Hamady Z, Primrose J, Takhar A, Walter L, Khakoo SI., Free PMC Article | 03/16/2019 |