| m[6]A-modified cenRNA stabilizes CENPA to ensure centromere integrity in cancer cells. | m(6)A-modified cenRNA stabilizes CENPA to ensure centromere integrity in cancer cells.
Kang Z, Li R, Liu C, Dong X, Hu Y, Xu L, Liu X, Xiang Y, Gao L, Si W, Wang L, Li Q, Zhang L, Wang H, Yang X, Liu J. | 10/28/2024 |
| beta-TrCP-Mediated Proteolysis of Mis18beta Prevents Mislocalization of CENP-A and Chromosomal Instability. | β-TrCP-Mediated Proteolysis of Mis18β Prevents Mislocalization of CENP-A and Chromosomal Instability.
Sethi SC, Shrestha RL, Balachandra V, Durairaj G, Au WC, Nirula M, Karpova TS, Kaiser P, Basrai MA., Free PMC Article | 10/16/2024 |
| Target Identification and Mechanistic Characterization of Indole Terpenoid Mimics: Proper Spindle Microtubule Assembly Is Essential for Cdh1-Mediated Proteolysis of CENP-A. | Target Identification and Mechanistic Characterization of Indole Terpenoid Mimics: Proper Spindle Microtubule Assembly Is Essential for Cdh1-Mediated Proteolysis of CENP-A.
Peng Y, Zhang Y, Fang R, Jiang H, Lan G, Xu Z, Liu Y, Nie Z, Ren L, Wang F, Zhang SD, Ma Y, Yang P, Ge HH, Zhang WD, Luo C, Li A, He W., Free PMC Article | 09/16/2024 |
| YTHDC1-dependent m6A modification modulated FOXM1 promotes glycolysis and tumor progression through CENPA in triple-negative breast cancer. | YTHDC1-dependent m6A modification modulated FOXM1 promotes glycolysis and tumor progression through CENPA in triple-negative breast cancer.
Shen X, Zhong J, Yu P, Liu F, Peng H, Chen N., Free PMC Article | 07/7/2024 |
| CENPA promotes glutamine metabolism and tumor progression by up-regulating SLC38A1 in endometrial cancer. | CENPA promotes glutamine metabolism and tumor progression by up-regulating SLC38A1 in endometrial cancer.
Li S, Zhang Z, Li Z, Yang L, Liu J, Liu Y, Liu Y, Hou Y, Mei M, Huang Y. | 03/15/2024 |
| CENPA functions as a transcriptional regulator to promote hepatocellular carcinoma progression via cooperating with YY1. | CENPA functions as a transcriptional regulator to promote hepatocellular carcinoma progression via cooperating with YY1.
Liao J, Chen Z, Chang R, Yuan T, Li G, Zhu C, Wen J, Wei Y, Huang Z, Ding Z, Chu L, Liang J, Zhang B., Free PMC Article | 11/21/2023 |
| The CENP-A nucleosome: where and when it happens during the inner kinetochore's assembly. | The CENP-A nucleosome: where and when it happens during the inner kinetochore's assembly.
Kale S, Boopathi R, Belotti E, Lone IN, Graies M, Schröder M, Petrova M, Papin C, Bednar J, Ugrinova I, Hamiche A, Dimitrov S. | 09/20/2023 |
| MLL methyltransferases regulate H3K4 methylation to ensure CENP-A assembly at human centromeres. | MLL methyltransferases regulate H3K4 methylation to ensure CENP-A assembly at human centromeres.
Malik KK, Sridhara SC, Lone KA, Katariya PD, Pulimamidi D, Tyagi S., Free PMC Article | 07/19/2023 |
| The Sequence Dependent Nanoscale Structure of CENP-A Nucleosomes. | The Sequence Dependent Nanoscale Structure of CENP-A Nucleosomes.
Stormberg T, Lyubchenko YL., Free PMC Article | 10/22/2022 |
| Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Yatskevich S, Muir KW, Bellini D, Zhang Z, Yang J, Tischer T, Predin M, Dendooven T, McLaughlin SH, Barford D., Free PMC Article | 05/28/2022 |
| Gene replacement strategies validate the use of functional tags on centromeric chromatin and invalidate an essential role for CENP-A(K124ub). | Gene replacement strategies validate the use of functional tags on centromeric chromatin and invalidate an essential role for CENP-A(K124ub).
Salinas-Luypaert C, Allu PK, Logsdon GA, Dawicki-McKenna JM, Gambogi CW, Fachinetti D, Black BE., Free PMC Article | 02/19/2022 |
| Centromere Protein A (CENPA) Regulates Metabolic Reprogramming in the Colon Cancer Cells by Transcriptionally Activating Karyopherin Subunit Alpha 2 (KPNA2). | Centromere Protein A (CENPA) Regulates Metabolic Reprogramming in the Colon Cancer Cells by Transcriptionally Activating Karyopherin Subunit Alpha 2 (KPNA2).
Liang YC, Su Q, Liu YJ, Xiao H, Yin HZ. | 12/11/2021 |
| CENP-A overexpression promotes aneuploidy with karyotypic heterogeneity. | CENP-A overexpression promotes aneuploidy with karyotypic heterogeneity.
Shrestha RL, Rossi A, Wangsa D, Hogan AK, Zaldana KS, Suva E, Chung YJ, Sanders CL, Difilippantonio S, Karpova TS, Karim B, Foltz DR, Fachinetti D, Aplan PD, Ried T, Basrai MA., Free PMC Article | 09/25/2021 |
| CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy. | CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy.
Giunta S, Hervé S, White RR, Wilhelm T, Dumont M, Scelfo A, Gamba R, Wong CK, Rancati G, Smogorzewska A, Funabiki H, Fachinetti D., Free PMC Article | 08/21/2021 |
| CENP-A overexpression promotes distinct fates in human cells, depending on p53 status. | CENP-A overexpression promotes distinct fates in human cells, depending on p53 status.
Jeffery D, Gatto A, Podsypanina K, Renaud-Pageot C, Ponce Landete R, Bonneville L, Dumont M, Fachinetti D, Almouzni G., Free PMC Article | 08/7/2021 |
| Centromeric chromatin integrity is compromised by loss of Cdk5rap2, a transcriptional activator of CENP-A. | Centromeric chromatin integrity is compromised by loss of Cdk5rap2, a transcriptional activator of CENP-A.
Wang X, Rosales JL, Gao X, Lee KY. | 07/24/2021 |
| CENP-A Nucleosome is a Sensitive Allosteric Scaffold for DNA and Chromatin Factors. | CENP-A Nucleosome is a Sensitive Allosteric Scaffold for DNA and Chromatin Factors.
Doğan D, Arslan M, Uluçay T, Kalyoncu S, Dimitrov S, Kale S. | 05/8/2021 |
| The Elusive Structure of Centro-Chromatin: Molecular Order or Dynamic Heterogenetity? | The Elusive Structure of Centro-Chromatin: Molecular Order or Dynamic Heterogenetity?
Nagpal H, Fierz B. | 05/8/2021 |
| A genetic memory initiates the epigenetic loop necessary to preserve centromere position. | A genetic memory initiates the epigenetic loop necessary to preserve centromere position.
Hoffmann S, Izquierdo HM, Gamba R, Chardon F, Dumont M, Keizer V, Hervé S, McNulty SM, Sullivan BA, Manel N, Fachinetti D., Free PMC Article | 04/17/2021 |
| Stable inheritance of CENP-A chromatin: Inner strength versus dynamic control. | Stable inheritance of CENP-A chromatin: Inner strength versus dynamic control.
Mitra S, Srinivasan B, Jansen LET., Free PMC Article | 03/28/2021 |
| Guarding the Genome: CENP-A-Chromatin in Health and Cancer. | Guarding the Genome: CENP-A-Chromatin in Health and Cancer.
Mahlke MA, Nechemia-Arbely Y., Free PMC Article | 03/6/2021 |
| The Oncogenic Role of CENPA in Hepatocellular Carcinoma Development: Evidence from Bioinformatic Analysis. | The Oncogenic Role of CENPA in Hepatocellular Carcinoma Development: Evidence from Bioinformatic Analysis.
Zhang Y, Yang L, Shi J, Lu Y, Chen X, Yang Z., Free PMC Article | 02/2/2021 |
| The role of the histone H3 variant CENPA in prostate cancer. | The role of the histone H3 variant CENPA in prostate cancer.
Saha AK, Contreras-Galindo R, Niknafs YS, Iyer M, Qin T, Padmanabhan K, Siddiqui J, Palande M, Wang C, Qian B, Ward E, Tang T, Tomlins SA, Gitlin SD, Sartor MA, Omenn GS, Chinnaiyan AM, Markovitz DM., Free PMC Article | 01/9/2021 |
| ""Lessons from the extremes: Epigenetic and genetic regulation in point monocentromere and holocentromere establishment on artificial chromosomes"". | "Lessons from the extremes: Epigenetic and genetic regulation in point monocentromere and holocentromere establishment on artificial chromosomes".
Wong CYY, Ling YH, Mak JKH, Zhu J, Yuen KWY. | 12/12/2020 |
| Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome. | Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome.
Takizawa Y, Ho CH, Tachiwana H, Matsunami H, Kobayashi W, Suzuki M, Arimura Y, Hori T, Fukagawa T, Ohi MD, Wolf M, Kurumizaka H. | 10/3/2020 |