| HTATIP2 Overexpression was Associated With a Good Prognosis in Gastric Cancer. | HTATIP2 Overexpression was Associated With a Good Prognosis in Gastric Cancer.
Park SY, Park JH, Yang JW, Jung EJ, Ju YT, Jeong CY, Kim JY, Park T, Park M, Lee YJ, Jeong SH., Free PMC Article | 02/6/2024 |
| HTATIP2 regulates arteriogenic activity in monocytes from patients with limb ischemia. | HTATIP2 regulates arteriogenic activity in monocytes from patients with limb ischemia.
Patel AS, Ludwinski FE, Mondragon A, Nuthall K, Saha P, Lyons O, Squadrito ML, Siow R, De Palma M, Smith A, Modarai B., Free PMC Article | 01/3/2024 |
| Genome-wide association study of the age of onset of type 1 diabetes reveals HTATIP2 as a novel T cell regulator. | Genome-wide association study of the age of onset of type 1 diabetes reveals HTATIP2 as a novel T cell regulator.
Cardinale CJ, Chang X, Wei Z, Qu HQ, Bradfield JP, Polychronakos C, Hakonarson H., Free PMC Article | 03/1/2023 |
| The potential role of human HIV-1 TAT-Interactive Protein 2 levels in the pathogenesis of contact dermatitis | The potential role of human HIV-1 TAT-Interactive Protein 2 levels in the pathogenesis of contact dermatitis.
Metin MS, Bilen H, Elmas ÖF, Akdeniz N., Free PMC Article | 01/8/2022 |
| TIP30 overcomes gefitinib resistance by regulating cytoplasmic and nuclear EGFR signaling in non-small-cell lung cancer. | TIP30 overcomes gefitinib resistance by regulating cytoplasmic and nuclear EGFR signaling in non-small-cell lung cancer.
Shuai S, Liao X, Wang H, Liu L, Mei S, Cao J, Wang S., Free PMC Article | 10/9/2021 |
| Clinical significance of changes in AFP, HTATIP2/TIP30, B7-H4 and inflammatory cytokines after transcatheter arterial chemoembolization. | Clinical significance of changes in AFP, HTATIP2/TIP30, B7-H4 and inflammatory cytokines after transcatheter arterial chemoembolization.
Zhang P, Chen Z, Chen L, Zang H, Zhu B, Shao W, Niu W. | 02/13/2021 |
| Here, we identified the tumor suppressor protein TIP30 as novel inhibitor of cardiac hypertrophy and dysfunction. The results are relevant for human disease, since the authors found diminished cardiac TIP30 levels in samples from patients suffering from end-stage heart failure or hypertrophic cardiomyopathy. | TIP30 counteracts cardiac hypertrophy and failure by inhibiting translational elongation.
Grund A, Szaroszyk M, Korf-Klingebiel M, Malek Mohammadi M, Trogisch FA, Schrameck U, Gigina A, Tiedje C, Gaestel M, Kraft T, Hegermann J, Batkai S, Thum T, Perrot A, Remedios CD, Riechert E, Völkers M, Doroudgar S, Jungmann A, Bauer R, Yin X, Mayr M, Wollert KC, Pich A, Xiao H, Katus HA, Bauersachs J, Müller OJ, Heineke J., Free PMC Article | 04/18/2020 |
| Serum Golgi protein-73, alpha-fetoprotein-L3 and Tat-interacting protein-30 levels were significantly different in the hepatocellular carcinoma patients compared to controls, and those with chronic hepatitis and liver cirrhosis (p<0.01 each). | Combined detection of AFP-L3, GP73 and TIP30 enhances diagnostic accuracy for HBV-related cirrhosis and hepatocellular carcinoma.
Yanming L, Yue C, Wencan C, Liangyin WU, Xijun L, Jiafeng Z, Fengping HE. | 02/22/2020 |
| These results suggest that TIP30, as a tumor suppressor in the bladder cancer, might be served as a target in cancer therapies in the future. | Overexpression of Tat-interacting protein 30 inhibits the proliferation, migration, invasion and promotes apoptosis in bladder cancer cells.
Li Y, Cai B, Chen S, Fu X, Pang X, Zhu X, Qi H, Tan W. | 11/3/2018 |
| Binding of HIV1 Tat to TIP30 enhanced epithelial-to-mesenchymal transition and metastasis by regulating the nuclear translocation of Snail. | Human immunodeficiency virus Tat-TIP30 interaction promotes metastasis by enhancing the nuclear translocation of Snail in lung cancer cell lines.
Liu YP, Chen CH, Yen CH, Tung CW, Chen CJ, Chen YA, Huang MS., Free PMC Article | 10/13/2018 |
| Cholangiocarcinoma patients who had high methylation of HTATIP2 and low methylation of UCHL1 showed longer overall survival than those with low HTATIP2 methylation and high UCHL1 methylation. | Aberrant methylation of HTATIP2 and UCHL1 as a predictive biomarker for cholangiocarcinoma.
Nanok C, Jearanaikoon P, Proungvitaya S, Limpaiboon T. | 08/18/2018 |
| the results suggest that downregulation of TIP30 may result from HBV infection, and subsequently promotes the progression of HCC. | Association of TIP30 expression and prognosis of hepatocellular carcinoma in patients with HBV infection.
Zhang X, Lv L, Ouyang X, Zhang S, Fang J, Cai L, Li D., Free PMC Article | 11/18/2017 |
| TIP30 expression is associated with a good prognosis in patients with tumors. | Tat-Interacting Protein 30 (TIP30) Expression Serves as a New Biomarker for Tumor Prognosis: A Systematic Review and Meta-Analysis.
Xu T, Jin Z, Yuan Y, Zheng H, Li C, Hou W, Guo Q, Hua B., Free PMC Article | 07/1/2017 |
| these data suggest that positive MCM2 and negative TIP30 expression are closely correlated with the clinical, pathological and biological parameters, in addition to poor prognosis in patients with gallbladder cancer. | MCM2 and TIP30 are prognostic markers in squamous cell/adenosquamous carcinoma and adenocarcinoma of the gallbladder.
Liu Z, Yang Z, Jiang S, Zou Q, Yuan Y, Li J, Li D, Liang L, Chen M, Chen S., Free PMC Article | 04/22/2017 |
| The results of the present study indicated that TIP30 may suppress oncogenesis and glioma progression, thereby improving the prognosis of patients with glioma. | Overexpression of TIP30 inhibits the growth and invasion of glioma cells.
Hu Y, Chen F, Liu F, Liu X, Huang N, Cai X, Sun Y, Li A, Luo R., Free PMC Article | 10/1/2016 |
| combination of sorafenib and metformin inhibits proliferation and invasion in vitro, prolongs median survival, and reduces lung metastasis of HCC in vivo. This effect is closely associated with the upregulation of TIP30 | Metformin inhibits the prometastatic effect of sorafenib in hepatocellular carcinoma by upregulating the expression of TIP30.
Guo Z, Cao M, You A, Gao J, Zhou H, Li H, Cui Y, Fang F, Zhang W, Song T, Li Q, Zhu X, Sun H, Zhang T., Free PMC Article | 08/27/2016 |
| Increased HMGB1 and cleaved caspase-3 stimulate the proliferation of tumor cells and are correlated with the poor prognosis in colorectal cancer | Increased HMGB1 and cleaved caspase-3 stimulate the proliferation of tumor cells and are correlated with the poor prognosis in colorectal cancer.
Zhang Z, Wang M, Zhou L, Feng X, Cheng J, Yu Y, Gong Y, Zhu Y, Li C, Tian L, Huang Q., Free PMC Article | 03/5/2016 |
| Data iindicate TIP30 was a marker in predicting the prognosis of esophageal squamous cell carcinoma (ESCC). | TGF-β1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma.
Bu F, Liu X, Li J, Chen S, Tong X, Ma C, Mao H, Pan F, Li X, Chen B, Xu L, Li E, Kou G, Han J, Guo S, Zhao J, Guo Y., Free PMC Article | 12/5/2015 |
| the present study showed that loss of HTATIP2 expression was a frequent event in glioma and is associated with poor prognosis. | Downregulation of HTATIP2 expression is associated with promoter methylation and poor prognosis in glioma.
Dong X, Deng Q, Nie X, Zhang M, Jia W, Chen C, Xu C, Xu R. | 06/20/2015 |
| The results suggest a novel and critical role of TIP30 involved in hepatocellular carcinoma progression and aggressiveness. | Decreased TIP30 promotes Snail-mediated epithelial-mesenchymal transition and tumor-initiating properties in hepatocellular carcinoma.
Zhu M, Yin F, Fan X, Jing W, Chen R, Liu L, Zhang L, Liu Y, Liang Y, Bu F, Tong X, Zheng H, Zhao J, Guo Y. | 06/20/2015 |
| Meta-analysis suggests that the rs2230199 C/G, rs1047286 C/T, rs11569536 G/A and rs2250656 A/G SNPs in the CC3 gene may be associated with age-related macular degeneration risk. | Nonsynonymous single nucleotide polymorphisms in the complement component 3 gene are associated with risk of age-related macular degeneration: a meta-analysis.
Qian-Qian Y, Yong Y, Jing Z, Xin B, Tian-Hua X, Chao S, Jia C. | 05/30/2015 |
| The combination of HTATIP2 and MVD predicts the converse survival of HCC with or without sorafenib intervention. | The combination of HTATIP2 expression and microvessel density predicts converse survival of hepatocellular carcinoma with or without sorafenib.
Wang WQ, Liu L, Xu HX, Sun HC, Wu CT, Zhu XD, Zhang W, Xu J, Liu C, Long J, Ni QX, Tang ZY, Yu XJ., Free PMC Article | 04/25/2015 |
| miR-10b promotes pancreatic cancer cell proliferation and invasion by suppressing TIP30. | microRNA-10b enhances pancreatic cancer cell invasion by suppressing TIP30 expression and promoting EGF and TGF-β actions.
Ouyang H, Gore J, Deitz S, Korc M., Free PMC Article | 11/22/2014 |
| TIP30-induced downregulation of cyclin D1 transcription antagonizes EGFR signaling and suppresses tumorigenesis | TIP30 nuclear translocation negatively regulates EGF-dependent cyclin D1 transcription in human lung adenocarcinoma.
Shuai S, Yan X, Zhang J, Kang S, Chen F, Luo R, Li A. | 11/22/2014 |
| Decreased TIP30 expression is associated with pancreatic cancer. | Decreased TIP30 expression predicts poor prognosis in pancreatic cancer patients.
Guo S, Jing W, Hu X, Zhou X, Liu L, Zhu M, Yin F, Chen R, Zhao J, Guo Y. | 03/1/2014 |