| FBLN5 was Regulated by PRDM9, and Promoted Senescence and Osteogenic Differentiation of Human Periodontal Ligament Stem Cells. | FBLN5 was Regulated by PRDM9, and Promoted Senescence and Osteogenic Differentiation of Human Periodontal Ligament Stem Cells.
Zhao M, Rong R, Zhang C, Yang H, Han X, Fan Z, Zheng Y, Zhang J., Free PMC Article | 01/12/2024 |
| Genetic screening for anticancer genes highlights FBLN5 as a synthetic lethal partner of MYC. | Genetic screening for anticancer genes highlights FBLN5 as a synthetic lethal partner of MYC.
Masood M, Ding Q, Cawte AD, Rueda DS, Grimm SW, Yagüe E, El-Bahrawy M., Free PMC Article | 11/3/2023 |
| Genetic variants and haplotypes in fibulin-5 (FBLN5) are associated with pseudoexfoliation glaucoma but not with pseudoexfoliation syndrome. | Genetic variants and haplotypes in fibulin-5 (FBLN5) are associated with pseudoexfoliation glaucoma but not with pseudoexfoliation syndrome.
Kapuganti RS, Bharati B, Mohanty PP, Alone DP., Free PMC Article | 03/10/2023 |
| Decreased Expression of EC-SOD and Fibulin-5 in Alveolar Walls of Lungs From COPD Patients. | Decreased Expression of EC-SOD and Fibulin-5 in Alveolar Walls of Lungs From COPD Patients.
García-Valero J, Olloquequi J, Rodríguez E, Martín-Satué M, Texidó L, Ferrer J. | 06/18/2022 |
| Knockdown of ubiquitin-conjugating enzyme E2T (UBE2T) suppresses lung adenocarcinoma progression via targeting fibulin-5 (FBLN5). | Knockdown of ubiquitin-conjugating enzyme E2T (UBE2T) suppresses lung adenocarcinoma progression via targeting fibulin-5 (FBLN5).
Li Y, Yang X, Lu D., Free PMC Article | 05/14/2022 |
| MiR-552-3p facilitated cell proliferation, migration and invasion by sponging Fibulin 5 in non-small cell lung cancer via activation of ERK/GSK3beta/beta-catenin signaling pathway. | MiR-552-3p facilitated cell proliferation, migration and invasion by sponging Fibulin 5 in non-small cell lung cancer via activation of ERK/GSK3β/β-catenin signaling pathway.
Huang M, Liao X, Li L, Li G, Chen M. | 03/5/2022 |
| PAD2-mediated citrullination of Fibulin-5 promotes elastogenesis. | PAD2-mediated citrullination of Fibulin-5 promotes elastogenesis.
Sun B, Tomita B, Salinger A, Tilvawala RR, Li L, Hakami H, Liu T, Tsoyi K, Rosas IO, Reinhardt DP, Thompson PR, Ho IC., Free PMC Article | 01/22/2022 |
| Demyelinating Charcot-Marie-Tooth neuropathy associated with FBLN5 mutations. | Demyelinating Charcot-Marie-Tooth neuropathy associated with FBLN5 mutations.
Safka Brozkova D, Stojkovic T, Haberlová J, Mazanec R, Windhager R, Fernandes Rosenegger P, Hacker S, Züchner S, Kochański A, Leonard-Louis S, Francou B, Latour P, Senderek J, Seeman P, Auer-Grumbach M. | 08/14/2021 |
| FBLN5 is targeted by microRNA27a3p and suppresses tumorigenesis and progression in highgrade serous ovarian carcinoma. | FBLN5 is targeted by microRNA‑27a‑3p and suppresses tumorigenesis and progression in high‑grade serous ovarian carcinoma.
Li R, Wu H, Jiang H, Wang Q, Dou Z, Ma H, Yan S, Yuan C, Yang N, Kong B., Free PMC Article | 07/24/2021 |
| Fibulin-5 protects the extracellular matrix of chondrocytes by inhibiting the Wnt/beta-catenin signaling pathway and relieves osteoarthritis. | Fibulin-5 protects the extracellular matrix of chondrocytes by inhibiting the Wnt/β-catenin signaling pathway and relieves osteoarthritis.
Gao JB, Lin L, Men XQ, Zhao JB, Zhang MH, Jin LP, Gao SJ, Zhao SQ, Dong JT. | 04/3/2021 |
| Network-based analysis reveals novel gene signatures in the peripheral blood of patients with sporadic nonsyndromic thoracic aortic aneurysm. | Network-based analysis reveals novel gene signatures in the peripheral blood of patients with sporadic nonsyndromic thoracic aortic aneurysm.
Xu H, Chen S, Zhang H, Zou Y, Zhao J, Yu J, Le S, Cui J, Jiang L, Wu J, Xia J. | 12/19/2020 |
| Identification of pelvic organ prolapse risk susceptibility gene SNP locus in Xinjiang women. | Identification of pelvic organ prolapse risk susceptibility gene SNP locus in Xinjiang women.
Abulaizi A, Abula A, Ababaikeli G, Wan X, Du R, Zhakeer A. | 12/5/2020 |
| Fibulin-5 contributes to colorectal cancer cell apoptosis via the ROS/MAPK and Akt signal pathways by downregulating transient receptor potential cation channel subfamily V member 1. | Fibulin-5 contributes to colorectal cancer cell apoptosis via the ROS/MAPK and Akt signal pathways by downregulating transient receptor potential cation channel subfamily V member 1.
Chen Y, Li J, Jin L, Lei K, Liu H, Yang Y. | 09/12/2020 |
| Evaluation of the fibulin 5 gene polymorphism as a factor related to the occurrence of pelvic organ prolapse. | Evaluation of the fibulin 5 gene polymorphism as a factor related to the occurrence of pelvic organ prolapse.
Paula MVB, Lira Júnior MAF, Monteiro VCESC, Souto RP, Fernandes CE, Oliveira E. | 09/5/2020 |
| This study unravels two novel risk variants within FBLN5 gene in the pathogenesis of pseudoexfoliation (PEX). Further, a decreased expression of FBLN5 in PEXS affected lens capsules implicates a pathogenic link between extracellular matrix maintenance and onset of PEX. | De novo variants in an extracellular matrix protein coding gene, fibulin-5 (FBLN5) are associated with pseudoexfoliation.
Padhy B, Kapuganti RS, Hayat B, Mohanty PP, Alone DP., Free PMC Article | 07/18/2020 |
| Fibulin-1 and -5 measurements might be used to exclude non-ST-elevation myocardial infarction (NSTEMI) in patients admitted to the emergency department with acute chest pain. | Fibulin‑1 and fibulin‑5 as rule‑out tests for non-ST‑elevation myocardial infarction in the emergency setting.
Zencir C, Sivri F, Gulasti S, Turkdogan AK, Yilmaz M, Gungor H. | 06/20/2020 |
| NOX1 and Fibulin-5 were increased and decreased in aortic dissection, respectively. NOX1 is a negative modulator of Fibulin-5. | NOX1 Negatively Modulates Fibulin-5 in Vascular Smooth Muscle Cells to Affect Aortic Dissection.
Hu X, Jiang W, Wang Z, Li L, Hu Z. | 02/1/2020 |
| Fibulin-5 is down-regulated in CRC and the reduced expression of fibulin-5 was correlated with malignant clinicopathological characteristics. | Fibulin-5 is Down-Regulated in Colorectal Cancer and Correlated with Clinicopathologic Characteristics.
Chen Z, Wang Z, Chen J, Li Z. | 09/14/2019 |
| Fibulin-5 silencing in non-small-cell lung cancer cells is due to the hypermethylation of its promoter through 2-hydroxyglutarate, production of which arises from a mutation in IDH1. | IDH1 mutation promotes lung cancer cell proliferation through methylation of Fibulin-5.
Yan B, Hu Y, Ma T, Wang Y., Free PMC Article | 07/20/2019 |
| We describe a novel, homozygous c.518A>G, p.R173H mutation in exon 6 of the FBLN5 gene, confirming the diagnosis of autosomal recessive cutis laxa. | Autosomal recessive cutis laxa: a novel mutation in the FBLN5 gene in a family.
Tekedereli I, Demiral E, Gokce IK, Esener Z, Camtosun E, Akinci A. | 06/15/2019 |
| study reports the first Chinese family with c.1117C>T mutation of FBLN5; findings confirm a novel subtype of autosomal-dominant Charcot-Marie-Tooth disease due to a mutation in the FBLN5 gene | Adult-onset demyelinating neuropathy associated with FBLN5 gene mutation.
Cheng S, Lv H, Zhang W, Wang Z, Shi X, Liang W, Yuan Y., Free PMC Article | 09/29/2018 |
| The results showed a significant upregulation of ECM1 and ITGB3, and a significant downregulation for FBLN5 in pelvic organ prolapse patients. | Expression of extracellular matrix and adhesion proteins in pelvic organ prolapse.
Cecati M, Corradetti A, Sartini D, Pozzi V, Giannubilo SR, Saccucci F, Ciavattini A, Emanuelli M. | 09/22/2018 |
| Serum fibulin-5 concentration can be regarded as a biomarker for evaluating disease severity and predicting prognosis in intracerebral hemorrhage patients. | Fibulin-5: a novel biomarker for evaluating severity and predicting prognosis in patients with acute intracerebral haemorrhage.
Hu L, Dong MX, Zhao H, Xu GH, Qin XY. | 01/13/2018 |
| Fibulin-5 expression is increased in the induced sputum of asthmatic patients. | Fibulin-5 promotes airway smooth muscle cell proliferation and migration via modulating Hippo-YAP/TAZ pathway.
Fu J, Zheng M, Zhang X, Zhang Y, Chen Y, Li H, Wang X, Zhang J. | 10/21/2017 |
| Data show that fibulin-5 strongly binds to the endothelial cell surface reducing endothelial cell viability and interfering with the signaling pathways of the Ang-1/TIE-2 receptor axis. | Fibulin-5 Regulates Angiopoietin-1/Tie-2 Receptor Signaling in Endothelial Cells.
Chan W, Ismail H, Mayaki D, Sanchez V, Tiedemann K, Davis EC, Hussain SN., Free PMC Article | 07/22/2017 |