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    GPNMB glycoprotein nmb [ Homo sapiens (human) ]

    Gene ID: 10457, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Glycoprotein non-metastatic melanoma protein B (GPNMB): An attractive target in atherosclerosis.

    Glycoprotein non-metastatic melanoma protein B (GPNMB): An attractive target in atherosclerosis.
    Yu X, Li M, Wang C, Guan X.

    09/9/2024
    The E3 ubiquitin-protein ligase UHRF1 promotes adipogenesis and limits fibrosis by suppressing GPNMB-mediated TGF-beta signaling.

    The E3 ubiquitin-protein ligase UHRF1 promotes adipogenesis and limits fibrosis by suppressing GPNMB-mediated TGF-β signaling.
    Vakayil M, Madani AY, Agha MV, Majeed Y, Hayat S, Yonuskunju S, Mohamoud YA, Malek J, Suhre K, Mazloum NA., Free PMC Article

    06/12/2024
    Glycoprotein non-metastatic melanoma protein B promotes tumor growth and is a biomarker for lymphangioleiomyomatosis.

    Glycoprotein non-metastatic melanoma protein B promotes tumor growth and is a biomarker for lymphangioleiomyomatosis.
    Gibbons E, Taya M, Wu H, Lopa SH, Moss J, Henske EP, McCormack FX, Hammes SR., Free PMC Article

    06/11/2024
    Glycoprotein nonmetastatic melanoma protein B impacts the malignant potential of bladder cancer cells through its hem-immunoreceptor tyrosine-based activation motif.

    Glycoprotein nonmetastatic melanoma protein B impacts the malignant potential of bladder cancer cells through its hem-immunoreceptor tyrosine-based activation motif.
    Kimura T, Okita Y, Nagumo Y, Chin JM, Fikry MA, Shiga M, Kandori S, Kawahara T, Suzuki H, Nishiyama H, Kato M.

    06/5/2024
    Tumor associated microglia/macrophages utilize GPNMB to promote tumor growth and alter immune cell infiltration in glioma.

    Tumor associated microglia/macrophages utilize GPNMB to promote tumor growth and alter immune cell infiltration in glioma.
    Yalcin F, Haneke H, Efe IE, Kuhrt LD, Motta E, Nickl B, Flüh C, Synowitz M, Dzaye O, Bader M, Kettenmann H., Free PMC Article

    04/5/2024
    The association between plasma GPNMB and Parkinson's disease and multiple system atrophy.

    The association between plasma GPNMB and Parkinson's disease and multiple system atrophy.
    Li K, Wang P, Li W, Yan JH, Ge YL, Zhang JR, Wang F, Mao CJ, Liu CF.

    02/27/2024
    HOMER3 promotes liver hepatocellular carcinoma cancer progression by -upregulating EZH2 and mediating miR-361/GPNMB axis.

    HOMER3 promotes liver hepatocellular carcinoma cancer progression by -upregulating EZH2 and mediating miR-361/GPNMB axis.
    Chen L, Shan X, Wan X, Zha W, Fan R.

    02/15/2024
    Gpnmb silencing protects against hyperoxia-induced acute lung injury by inhibition of mitochondrial-mediated apoptosis.

    Gpnmb silencing protects against hyperoxia-induced acute lung injury by inhibition of mitochondrial-mediated apoptosis.
    Wang X, Qin S, Ren Y, Feng B, Liu J, Yu K, Yu H, Liao Z, Mei H, Tan M.

    01/4/2024
    Glycoprotein Non-Metastatic Protein B (GPNMB): The Missing Link Between Lysosomes and Obesity.

    Glycoprotein Non-Metastatic Protein B (GPNMB): The Missing Link Between Lysosomes and Obesity.
    Bianco V, Kratky D., Free PMC Article

    12/16/2023
    Prognostic evaluation of oral squamous cell carcinoma based on pleiotrophin, urokinase plasminogen activator, and glycoprotein nonmetastatic melanoma protein B expression.

    Prognostic evaluation of oral squamous cell carcinoma based on pleiotrophin, urokinase plasminogen activator, and glycoprotein nonmetastatic melanoma protein B expression.
    Ma Y, Liu Y, Meng H., Free PMC Article

    11/18/2023
    miR-532-3p suppresses proliferation and invasion of ovarian cancer cells via GPNMB/HIF-1alpha/HK2 axis.

    miR-532-3p suppresses proliferation and invasion of ovarian cancer cells via GPNMB/HIF-1α/HK2 axis.
    Tuo X, Zhou Y, Yang X, Ma S, Liu D, Zhang X, Hou H, Wang R, Li X, Zhao L.

    10/29/2022
    GPNMB: a potent inducer of immunosuppression in cancer.

    GPNMB: a potent inducer of immunosuppression in cancer.
    Lazaratos AM, Annis MG, Siegel PM.

    10/15/2022
    GPNMB-Positive Cells in Head and Neck Squamous Cell Carcinoma-Their Roles in Cancer Stemness, Therapy Resistance, and Metastasis.

    GPNMB-Positive Cells in Head and Neck Squamous Cell Carcinoma-Their Roles in Cancer Stemness, Therapy Resistance, and Metastasis.
    Kawasaki Y, Suzuki H, Suzuki S, Yamada T, Suzuki M, Ito A, Hatakeyama H, Miura M, Omori Y., Free PMC Article

    09/17/2022
    GPNMB confers risk for Parkinson's disease through interaction with alpha-synuclein.

    GPNMB confers risk for Parkinson's disease through interaction with α-synuclein.
    Diaz-Ortiz ME, Seo Y, Posavi M, Carceles Cordon M, Clark E, Jain N, Charan R, Gallagher MD, Unger TL, Amari N, Skrinak RT, Davila-Rivera R, Brody EM, Han N, Zack R, Van Deerlin VM, Tropea TF, Luk KC, Lee EB, Weintraub D, Chen-Plotkin AS., Free PMC Article

    09/3/2022
    Glycoprotein nonmetastatic melanoma protein B (GNMPB) as a novel biomarker for cerebral adrenoleukodystrophy.

    Glycoprotein nonmetastatic melanoma protein B (GNMPB) as a novel biomarker for cerebral adrenoleukodystrophy.
    Taghizadeh LA, King CJ, Nascene DR, Gupta AO, Orchard PJ, Higgins L, Markowski TW, Nolan EE, Furcich JW, Lund TC., Free PMC Article

    05/28/2022
    GPNMB expression identifies TSC1/2/mTOR-associated and MiT family translocation-driven renal neoplasms.

    GPNMB expression identifies TSC1/2/mTOR-associated and MiT family translocation-driven renal neoplasms.
    Salles DC, Asrani K, Woo J, Vidotto T, Liu HB, Vidal I, Matoso A, Netto GJ, Argani P, Lotan TL., Free PMC Article

    05/7/2022
    GPNMB plays an active role in the M1/M2 balance.

    GPNMB plays an active role in the M1/M2 balance.
    Zhang H, Zhang S, Dang X, Lin L, Ren L, Song R.

    03/26/2022
    Two missense mutations in GPNMB cause autosomal recessive amyloidosis cutis dyschromica in the consanguineous pakistani families.

    Two missense mutations in GPNMB cause autosomal recessive amyloidosis cutis dyschromica in the consanguineous pakistani families.
    Rahman OU, Kim J, Mahon C, Jelani M, Kang C.

    03/19/2022
    Genetic ablation of Gpnmb does not alter synuclein-related pathology.

    Genetic ablation of Gpnmb does not alter synuclein-related pathology.
    Brendza R, Lin H, Stark K, Foreman O, Tao J, Pierce A, Ngu H, Shen K, Easton AE, Bhangale T, Chang D, Bingol B, Friedman BA.

    03/5/2022
    Amyloidosis cutis dyschromica cases caused by GPNMB mutations with different inheritance patterns.

    Amyloidosis cutis dyschromica cases caused by GPNMB mutations with different inheritance patterns.
    Qin W, Wang H, Zhong W, Bai J, Qiao J, Lin Z.

    02/19/2022
    Association Between Factors Involved in Bone Remodeling (Osteoactivin and OPG) With Plasma Levels of Irisin and Meteorin-Like Protein in People With T2D and Obesity.

    Association Between Factors Involved in Bone Remodeling (Osteoactivin and OPG) With Plasma Levels of Irisin and Meteorin-Like Protein in People With T2D and Obesity.
    Cherian P, Al-Khairi I, Jamal M, Al-Sabah S, Ali H, Dsouza C, Alshawaf E, Al-Ali W, Al-Khaledi G, Al-Mulla F, Abu-Farha M, Abubaker J., Free PMC Article

    02/12/2022
    Mapping the serum proteome to neurological diseases using whole genome sequencing.

    Mapping the serum proteome to neurological diseases using whole genome sequencing.
    Png G, Barysenka A, Repetto L, Navarro P, Shen X, Pietzner M, Wheeler E, Wareham NJ, Langenberg C, Tsafantakis E, Karaleftheri M, Dedoussis G, Mälarstig A, Wilson JF, Gilly A, Zeggini E., Free PMC Article

    01/8/2022
    The soluble glycoprotein NMB (GPNMB) produced by macrophages induces cancer stemness and metastasis via CD44 and IL-33.

    The soluble glycoprotein NMB (GPNMB) produced by macrophages induces cancer stemness and metastasis via CD44 and IL-33.
    Liguori M, Digifico E, Vacchini A, Avigni R, Colombo FS, Borroni EM, Farina FM, Milanesi S, Castagna A, Mannarino L, Craparotta I, Marchini S, Erba E, Panini N, Tamborini M, Rimoldi V, Allavena P, Belgiovine C., Free PMC Article

    01/1/2022
    Expression pattern and prognostic impact of glycoprotein non-metastatic B (GPNMB) in triple-negative breast cancer.

    Expression pattern and prognostic impact of glycoprotein non-metastatic B (GPNMB) in triple-negative breast cancer.
    Huang YH, Chu PY, Chen JL, Huang CT, Huang CC, Tsai YF, Wang YL, Lien PJ, Tseng LM, Liu CY., Free PMC Article

    11/6/2021
    Elevated Circulating Levels of Glycoprotein Non-Metastatic Melanoma Protein B as a Predictor of Gestational Diabetes Mellitus.

    Elevated Circulating Levels of Glycoprotein Non-Metastatic Melanoma Protein B as a Predictor of Gestational Diabetes Mellitus.
    Cao C, Wei L, Han Y, Wang Y, Zhang J, Zhang L, Kang Z, Zhang J.

    09/25/2021
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