| BRG1 promotes liver cancer cell proliferation and metastasis by enhancing mitochondrial function and ATP5A1 synthesis through TOMM40. | BRG1 promotes liver cancer cell proliferation and metastasis by enhancing mitochondrial function and ATP5A1 synthesis through TOMM40.
Hui Y, Leng J, Jin D, Wang G, Liu K, Bu Y, Wang Q., Free PMC Article | 07/26/2024 |
| Alzheimer's disease cortical morphological phenotypes are associated with TOMM40'523-APOE haplotypes. | Alzheimer's disease cortical morphological phenotypes are associated with TOMM40'523-APOE haplotypes.
Honea RA, Hunt S, Lepping RJ, Vidoni ED, Morris JK, Watts A, Michaelis E, Burns JM, Swerdlow RH., Free PMC Article | 12/5/2023 |
| TOMM40 '523 Genotype Distinguishes Patterns of Cognitive Improvement for Executive Function in APOEvarepsilon3 Homozygotes. | TOMM40 '523 Genotype Distinguishes Patterns of Cognitive Improvement for Executive Function in APOEɛ3 Homozygotes.
Watts A, Haneline S, Welsh-Bohmer KA, Wu J, Alexander R, Swerdlow RH, Burns DK, Saunders AM., Free PMC Article | 11/8/2023 |
| Genotypic Effects of the TOMM40'523 Variant and APOE on Longitudinal Cognitive Change over 4 Years: The TOMMORROW Study. | Genotypic Effects of the TOMM40'523 Variant and APOE on Longitudinal Cognitive Change over 4 Years: The TOMMORROW Study.
Zou H, Luo S, Liu H, Lutz MW, Bennett DA, Plassman BL, Welsh-Bohmer KA., Free PMC Article | 10/25/2023 |
| TOMM40 Genetic Variants Cause Neuroinflammation in Alzheimer's Disease. | TOMM40 Genetic Variants Cause Neuroinflammation in Alzheimer's Disease.
Chen YC, Chang SC, Lee YS, Ho WM, Huang YH, Wu YY, Chu YC, Wu KH, Wei LS, Wang HL, Chiu CC., Free PMC Article | 03/28/2023 |
| Associations of the APOE epsilon2 and epsilon4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease biomarkers. | Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease biomarkers.
Kulminski AM, Jain-Washburn E, Loiko E, Loika Y, Feng F, Culminskaya I, Alzheimer’s Disease Neuroimaging Initiative., Free PMC Article | 01/14/2023 |
| MicroRNA-22-3p Restrains the Proliferation, Phenotypic Transformation, and Migration of Vascular Smooth Muscle Cells by Manipulating TOMM40. | MicroRNA-22-3p Restrains the Proliferation, Phenotypic Transformation, and Migration of Vascular Smooth Muscle Cells by Manipulating TOMM40.
Tan W, Yang Y, Bao H, Kang X, Zeng H, Hong L, Shao L. | 01/7/2023 |
| TOMM40 genetic variants associated with healthy aging and longevity: a systematic review. | TOMM40 genetic variants associated with healthy aging and longevity: a systematic review.
Chen S, Sarasua SM, Davis NJ, DeLuca JM, Boccuto L, Thielke SM, Yu CE., Free PMC Article | 08/27/2022 |
| Association and interaction of TOMM40 and PVRL2 with plasma amyloid-beta and Alzheimer's disease among Chinese older adults: a population-based study. | Association and interaction of TOMM40 and PVRL2 with plasma amyloid-β and Alzheimer's disease among Chinese older adults: a population-based study.
Liang X, Liu C, Liu K, Cong L, Wang Y, Liu R, Fa W, Tian N, Cheng Y, Wang N, Hou T, Du Y, Qiu C. | 04/30/2022 |
| APOE, TOMM40, and sex interactions on neural network connectivity. | APOE, TOMM40, and sex interactions on neural network connectivity.
Li T, Pappas C, Le ST, Wang Q, Klinedinst BS, Larsen BA, Pollpeter A, Lee LY, Lutz MW, Gottschalk WK, Swerdlow RH, Nho K, Willette AA., Free PMC Article | 02/19/2022 |
| Definitive roles of TOMM40-APOE-APOC1 variants in the Alzheimer's risk. | Definitive roles of TOMM40-APOE-APOC1 variants in the Alzheimer's risk.
Kulminski AM, Philipp I, Shu L, Culminskaya I., Free PMC Article | 02/19/2022 |
| Protective association of the epsilon2/epsilon3 heterozygote with Alzheimer's disease is strengthened by TOMM40-APOE variants in men. | Protective association of the ε2/ε3 heterozygote with Alzheimer's disease is strengthened by TOMM40-APOE variants in men.
Kulminski AM, Philipp I, Loika Y, He L, Culminskaya I., Free PMC Article | 02/5/2022 |
| The TOMM40 '523' polymorphism in disease risk and age of symptom onset in two independent cohorts of Parkinson's disease. | The TOMM40 '523' polymorphism in disease risk and age of symptom onset in two independent cohorts of Parkinson's disease.
Bakeberg MC, Hoes ME, Gorecki AM, Theunissen F, Pfaff AL, Kenna JE, Plunkett K, Kõks S, Akkari PA, Mastaglia FL, Anderton RS., Free PMC Article | 10/16/2021 |
| TOMM40 RNA Transcription in Alzheimer's Disease Brain and Its Implication in Mitochondrial Dysfunction. | TOMM40 RNA Transcription in Alzheimer's Disease Brain and Its Implication in Mitochondrial Dysfunction.
Lee EG, Chen S, Leong L, Tulloch J, Yu CE., Free PMC Article | 09/25/2021 |
| Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer's dementia. | Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer's dementia.
Tang S, Buchman AS, De Jager PL, Bennett DA, Epstein MP, Yang J., Free PMC Article | 08/28/2021 |
| DNA methylation QTL analysis identifies new regulators of human longevity. | DNA methylation QTL analysis identifies new regulators of human longevity.
Szymczak S, Dose J, Torres GG, Heinsen FA, Venkatesh G, Datlinger P, Nygaard M, Mengel-From J, Flachsbart F, Klapper W, Christensen K, Lieb W, Schreiber S, Häsler R, Bock C, Franke A, Nebel A., Free PMC Article | 08/7/2021 |
| TOMM40 and APOE variants synergistically increase the risk of Alzheimer's disease in a Chinese population. | TOMM40 and APOE variants synergistically increase the risk of Alzheimer's disease in a Chinese population.
Zhu Z, Yang Y, Xiao Z, Zhao Q, Wu W, Liang X, Luo J, Cao Y, Shao M, Guo Q, Ding D. | 06/19/2021 |
| A TOMM40/APOE allele encoding APOE-E3 predicts high likelihood of late-onset Alzheimer's disease in autopsy cases. | A TOMM40/APOE allele encoding APOE-E3 predicts high likelihood of late-onset Alzheimer's disease in autopsy cases.
Soyal SM, Kwik M, Kalev O, Lenz S, Zara G, Strasser P, Patsch W, Weis S., Free PMC Article | 05/15/2021 |
| TOMM40 '523 Associations with Baseline and Longitudinal Cognition in APOE varepsilon3 Homozygotes. | TOMM40 '523 Associations with Baseline and Longitudinal Cognition in APOE ɛ3 Homozygotes.
Watts A, Wilkins HM, Michaelis E, Swerdlow RH., Free PMC Article | 10/10/2020 |
| Genome-wide association study of hippocampal atrophy rate in non-demented elders. | Genome-wide association study of hippocampal atrophy rate in non-demented elders.
Guo Y, Xu W, Li JQ, Ou YN, Shen XN, Huang YY, Dong Q, Tan L, Yu JT., Free PMC Article | 10/3/2020 |
| that TOMM40 rs157581-G plays a harmful role in Alzheimer's disease patients | TOMM40 polymorphism is associated with resting-state functional MRI results in patients with Alzheimer's disease.
Xiao X, Wei J, Zhang W, Jiao B, Liao X, Pan C, Liu X, Yan X, Tang B, Zhang Y, Wang D, Xing W, Liao W, Shen L. | 07/18/2020 |
| BAP31 interacts with mitochondria-localized proteins, including Tom40, to stimulate the translocation of NDUFS4, the component of complex I from the cytosol to the mitochondria. | BAP31 regulates mitochondrial function via interaction with Tom40 within ER-mitochondria contact sites.
Namba T., Free PMC Article | 05/2/2020 |
| The connection between the success of the acquisition of the brain-computer, eye-tracking, electromyographic, and respiratory interfaces and SNP of the TOMM40, BDNF, HTR2A and TPH2 genes. | Connection between polymorphisms in HTR2A, TPH2, BDNF, TOMM40 genes and the successful mastering of human-computer interfaces.
Turovsky YA, Gureev AP, Vitkalova IY, Popov VN. | 04/11/2020 |
| TOMM40 and APOE variants are independently and additively associated with body mass index. | Independent associations of TOMM40 and APOE variants with body mass index.
Kulminski AM, Loika Y, Culminskaya I, Huang J, Arbeev KG, Bagley O, Feitosa MF, Zmuda JM, Christensen K, Yashin AI, Long Life Family Study Research Group., Free PMC Article | 04/4/2020 |
| TOM40 over-expression blocked Ab-elicited decreases in the mitochondrial membrane potential, cellular ATP levels, and cellular viability in the control cells. These data suggest elevated expression of TOM40 may be protective of mitochondrial function. | The biological foundation of the genetic association of TOMM40 with late-onset Alzheimer's disease.
Zeitlow K, Charlambous L, Ng I, Gagrani S, Mihovilovic M, Luo S, Rock DL, Saunders A, Roses AD, Gottschalk WK., Free PMC Article | 12/1/2018 |