Long noncoding RNA GHET1 promotes cell proliferation through oxidative stress in prostate cancer. | Long noncoding RNA GHET1 promotes cell proliferation through oxidative stress in prostate cancer. Wen Y, Huang H, Huang B, Liao X. | 07/21/2023 |
A review on the role of GHET1 in different cancers. | A review on the role of GHET1 in different cancers. Ghafouri-Fard S, Ahmadi Teshnizi S, Hussen BM, Taheri M, Zali H. | 06/16/2023 |
LncRNA GHET1 promotes osteoblast proliferation and differentiation by inhibiting PTEN. | LncRNA GHET1 promotes osteoblast proliferation and differentiation by inhibiting PTEN. Li D, Li L, Chen X, Gao Y, Cao Y, Hao B. | 03/26/2022 |
LncRNA GHET1 promotes cervical cancer progression through regulating AKT/mTOR and Wnt/beta-catenin signaling pathways. | LncRNA GHET1 promotes cervical cancer progression through regulating AKT/mTOR and Wnt/β-catenin signaling pathways. Liu Z, Luo S, Wu M, Huang C, Shi H, Song X., Free PMC Article | 03/20/2021 |
Long noncoding RNA GHET1 promotes osteosarcoma development and progression via Wnt/betacatenin signaling pathway. | Long non‑coding RNA GHET1 promotes osteosarcoma development and progression via Wnt/β‑catenin signaling pathway. Chen X, Zhao W, Fan W. | 03/13/2021 |
Knockdown of long non-coding RNA GHET1 suppresses cervical carcinoma in vitro and in vivo. | Knockdown of long non-coding RNA GHET1 suppresses cervical carcinoma in vitro and in vivo. Ling W, Yangchun X, Wei W, Qiang W. | 02/6/2021 |
Prognostic significance of LncRNA GHET1 expression in various cancers: a systematic review and meta-analysis. | Prognostic significance of LncRNA GHET1 expression in various cancers: a systematic review and meta-analysis. Ye J, Sun H, Feng Z, Zhang Q, Xia Y, Ji Y, Zhang Q., Free PMC Article | 10/3/2020 |
lncRNA GHET1 has effects in development of pre-eclampsia. | lncRNA GHET1 has effects in development of pre-eclampsia. Li S, Liu J, Kong F, Wang Y, Li N, Zou Y. | 09/19/2020 |
The GHET1 might promote U251 cells by down-regulating miR-216a. | Long non-coding RNA GHET1 promotes viability, migration and invasion of glioma cell line U251 by down-regulation of miR-216a. Cao W, Liu B, Ma H. | 08/1/2020 |
Findings indicate that non-coding RNA gastric carcinoma high expressed transcript 1 (GHET1) interacted with von Hippel-Lindau (VHL) and up-regulated hypoxia inducible factor 1 subunit alpha (HIF1alpha). | Long non-coding RNA GEHT1 promoted the proliferation of ovarian cancer cells via modulating the protein stability of HIF1α. Liu D, Li H., Free PMC Article | 07/11/2020 |
GHET1 expression is significantly increased in cervical cancer.GHET1 role in the cervical cancer cell proliferation, migration, and invasion. | GHET1 acts as a prognostic indicator and functions as an oncogenic lncRNA in cervical cancer. Zhang Q, Zhang Y, Wang Y., Free PMC Article | 06/20/2020 |
Elevated lncRNA GHET1 levels in cancer tissues are significantly related to a greater risk of mortality, progression, and metastasis. Therefore, lncRNA GHET1 could be used as a novel clinical biomarker. [Meta-Analysis] | The Value of lncRNA GHET1 as a Prognostic Factor for Survival of Chinese Cancer Outcome: A Meta-Analysis. Song J, Chen X, Tian Q, Lun L, Wang Q, Wang H, Li X, Liu Z, Tian L, Jing X, Zhang Y, Tian R., Free PMC Article | 05/9/2020 |
High expression of GHET1 was related with the low sensitivity to Gemcitabine of bladder cancer; GHET1 contributed to chemotherapeutic resistance to Gemcitabine through up-regulating ABCC1 expression. | Long non-coding RNA GHET1 contributes to chemotherapeutic resistance to Gemcitabine in bladder cancer. Li B, Xie D, Zhang H. | 03/28/2020 |
LncRNA GHET1 might be a biomarker and molecular target of non-small cell lung cancer (NSCLC), providing a potential therapeutic target of NSCLC | LncRNA GHET1 predicts a poor prognosis of the patients with non-small cell lung cancer. Shen QM, Wang HY, Xu S. | 11/2/2019 |
GHET1 could epigenetically repress transcription of Kruppel-like factor 2 in hepatocellular carcinoma cells by recruiting PRC2 into KLF2 promoter region and predicts poor prognosis. | LncRNA GHET1 predicts poor prognosis in hepatocellular carcinoma and promotes cell proliferation by silencing KLF2. Jin L, He Y, Tang S, Huang S. | 04/20/2019 |
GHET1 was up-regulated in osteosarcoma tissues and cell lines, inhibited cell apoptosis, promoted cell proliferation, invasion and migration by affecting EMT in vitro, and was correlated with the tumor growth and metastasis in vivo. GHET1 may be a potential therapeutic target of osteosarcoma treatment | Knockdown of lncRNA GHET1 inhibits osteosarcoma cells proliferation, invasion, migration and EMT in vitro and in vivo. Yang W, Shan Z, Zhou X, Peng L, Zhi C, Chai J, Liu H, Yang J, Zhang Z. | 04/6/2019 |
The GHET1 performs key functions in carcinogenesis and progression, suggesting that GHET1 is expected to be a prospective biomarker or therapeutic target for cancers. | Long noncoding RNA GHET1 in human cancer. Li J, Jiang X, Li Z, Huang L, Zhou Y, Liu Y, Cui Y. | 03/2/2019 |
the downregulation of GHET1 not only inhibits the migration and invasion of gastric cancer cells, but also inhibits their proliferation, at least in part by upregulating P21 expression and downregulating cyclin and CDK expression to inhibit the G0/G1 to S phase transition. | Knockdown of long noncoding RNA GHET1 inhibits cell‑cycle progression and invasion of gastric cancer cells. Xia Y, Yan Z, Wan Y, Wei S, Bi Y, Zhao J, Liu J, Liao DJ, Huang H., Free PMC Article | 11/10/2018 |
Our results demonstrated that GHET1 was up-regulated in breast cancer tissues and cell lines, and promoted breast cancer cell proliferation, invasion and migration by affecting EMT. | Long non-coding RNA GHET1 promotes human breast cancer cell proliferation, invasion and migration via affecting epithelial mesenchymal transition. Song R, Zhang J, Huang J, Hai T. | 10/20/2018 |
GHET1 were significantly upregulated in NSCLC tissues and cells. Furthermore, inhibition of GHET suppressed cell proliferation, invasion and EMT process. | Knockdown of lncRNA GHET1 suppresses cell proliferation, invasion and LATS1/YAP pathway in non small cell lung cancer. Guan ZB, Cao YS, Li Y, Tong WN, Zhuo AS. | 09/1/2018 |
GHET1 was relatively highly expressed in pancreatic cancer tissues and cells, and the highly expressed GHET1 was positively correlated with TNM staging. The inhibition of GHET1 expression inhibited the proliferation capacity of tumor cells, arrested cell cycle in G1/G0 phase and promoted apoptosis. | Expression and clinical significance of long-non-coding RNA GHET1 in pancreatic cancer. Zhou HY, Zhu H, Wu XY, Chen XD, Qiao ZG, Ling X, Yao XM, Tang JH. | 07/28/2018 |
Our study indicates that GHET1 acts as an oncogene in esophageal squamous cell carcinoma (ESCC)and may represent a novel therapeutic target for the treatment of ESCC patients. | LncRNA GHET1 promotes esophageal squamous cell carcinoma cells proliferation and invasion via induction of EMT. Liu H, Zhen Q, Fan Y. | 06/16/2018 |
LncRNA GHET1 was intimately involved in the occurrence and development of HCC through regulating ATF1. | LncRNA GHET1 activated by H3K27 acetylation promotes cell tumorigenesis through regulating ATF1 in hepatocellular carcinoma. Ding G, Li W, Liu J, Zeng Y, Mao C, Kang Y, Shang J. | 05/19/2018 |
GHET1 gene and protein expressions were significantly increased in gastric cancer tissues. | Knockdown of long noncoding RNA GHET1 inhibits cell activation of gastric cancer. Huang H, Liao W, Zhu X, Liu H, Cai L. | 04/7/2018 |
the expression of GHET1 was significantly upregulated in CRC tissues compared with the matched adjacent normal tissues. We also showed that GHET1 promoted the proliferation and invasion of CRC cells. | Knockdown of Long Noncoding RNA GHET1 Inhibits Cell Proliferation and Invasion of Colorectal Cancer. Zhou J, Li X, Wu M, Lin C, Guo Y, Tian B., Free PMC Article | 03/18/2017 |