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    OLIG2 oligodendrocyte transcription factor 2 [ Homo sapiens (human) ]

    Gene ID: 10215, updated on 10-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    OLIG2 translocates to chromosomes during mitosis via a temperature downshift: A novel neural cold response of mitotic bookmarking.

    OLIG2 translocates to chromosomes during mitosis via a temperature downshift: A novel neural cold response of mitotic bookmarking.
    Hayashi S, Seki-Omura R, Yamada S, Kamata T, Sato Y, Oe S, Koike T, Nakano Y, Iwashita H, Hirahara Y, Tanaka S, Sekijima T, Ito T, Yasukochi Y, Higasa K, Kitada M.

    10/24/2023
    OLIG2 expression level could be used as an independent prognostic factor for patients with cerebellar Glioblastoma (cGBM).

    OLIG2 expression level could be used as an independent prognostic factor for patients with cerebellar Glioblastoma (cGBM).
    Zhou J, Shi LF, Wang Z, Li M, Zhang JS, Mao Y, Hua W., Free PMC Article

    04/7/2023
    Identifying an oligodendrocyte enhancer that regulates Olig2 expression.

    Identifying an oligodendrocyte enhancer that regulates Olig2 expression.
    Fan C, Kim D, An H, Park Y., Free PMC Article

    02/24/2023
    OLIG2 Is a Determinant for the Relapse of MYC-Amplified Medulloblastoma.

    OLIG2 Is a Determinant for the Relapse of MYC-Amplified Medulloblastoma.
    Xu Z, Murad N, Malawsky D, Tao R, Rivero-Hinojosa S, Holdhof D, Schüller U, Zhang P, Lazarski C, Rood BR, Packer R, Gershon T, Pei Y., Free PMC Article

    10/8/2022
    Investigation of OLIG2 as a candidate gene for schizophrenia and autism spectrum disorder.

    Investigation of OLIG2 as a candidate gene for schizophrenia and autism spectrum disorder.
    Furuta S, Aleksic B, Nawa Y, Kimura H, Kushima I, Ishizuka K, Kato H, Toyama M, Arioka Y, Mori D, Morikawa M, Inada T, Ozaki N., Free PMC Article

    09/10/2022
    Isocitrate Dehydrogenase Mutations Are Associated with Different Expression and DNA Methylation Patterns of OLIG2 in Adult Gliomas.

    Isocitrate Dehydrogenase Mutations Are Associated with Different Expression and DNA Methylation Patterns of OLIG2 in Adult Gliomas.
    Mo H, Magaki S, Deisch JK, Raghavan R., Free PMC Article

    09/3/2022
    The Epigenetic Regulation of OLIG2 by Histone Demethylase KDM6B in Glioma Cells.

    The Epigenetic Regulation of OLIG2 by Histone Demethylase KDM6B in Glioma Cells.
    Sui A, Han B, Ren W, He W, Gao C, Han X, Liu S, Zhang Y, Qi X, Guo X.

    05/7/2022
    One-step Reprogramming of Human Fibroblasts into Oligodendrocyte-like Cells by SOX10, OLIG2, and NKX6.2.

    One-step Reprogramming of Human Fibroblasts into Oligodendrocyte-like Cells by SOX10, OLIG2, and NKX6.2.
    Chanoumidou K, Hernández-Rodríguez B, Windener F, Thomas C, Stehling M, Mozafari S, Albrecht S, Ottoboni L, Antel J, Kim KP, Velychko S, Cui QL, Xu YKT, Martino G, Winkler J, Schöler HR, Baron-Van Evercooren A, Boespflug-Tanguy O, Vaquerizas JM, Ehrlich M, Kuhlmann T., Free PMC Article

    03/5/2022
    Can oligodendrocyte transcriptional factor-2 (Olig2) be used as an alternative for 1p/19q co-deletions to distinguish oligodendrogliomas from other glial neoplasms?

    Can oligodendrocyte transcriptional factor-2 (Olig2) be used as an alternative for 1p/19q co-deletions to distinguish oligodendrogliomas from other glial neoplasms?
    Kurdi M, Alkhatabi H, Butt N, Albayjani H, Aljhdali H, Mohamed F, Alsinani T, Baeesa S, Almuhaini E, Al-Ghafari A, Hakamy S, Faizo E, Bahakeem B.

    02/12/2022
    Profiling Glioblastoma Cases with an Expression of DCX, OLIG2 and NES.

    Profiling Glioblastoma Cases with an Expression of DCX, OLIG2 and NES.
    Odrzywolski A, Jarosz B, Kiełbus M, Telejko I, Ziemianek D, Knaga S, Rola R., Free PMC Article

    02/5/2022
    Olig2 SUMOylation protects against genotoxic damage response by antagonizing p53 gene targeting.

    Olig2 SUMOylation protects against genotoxic damage response by antagonizing p53 gene targeting.
    Liu H, Weng W, Guo R, Zhou J, Xue J, Zhong S, Cheng J, Zhu MX, Pan SJ, Li Y., Free PMC Article

    11/22/2021
    Olig2 regulates p53-mediated apoptosis, migration and invasion of melanoma cells.

    Olig2 regulates p53-mediated apoptosis, migration and invasion of melanoma cells.
    Lee JE, Ahn S, Jeong H, An S, Myung CH, Lee JA, Hong SC, Kim YJ, Kim JY, Ryu JH, Noh M, Nam KT, Hwang JS., Free PMC Article

    11/13/2021
    Gene clusters based on OLIG2 and CD276 could distinguish molecular profiling in glioblastoma.

    Gene clusters based on OLIG2 and CD276 could distinguish molecular profiling in glioblastoma.
    Fu M, Zhang J, Li W, He S, Zhang J, Tennant D, Hua W, Mao Y., Free PMC Article

    11/6/2021
    Ethnicity-Dependent Effects of Schizophrenia Risk Variants of the OLIG2 Gene on OLIG2 Transcription and White Matter Integrity.

    Ethnicity-Dependent Effects of Schizophrenia Risk Variants of the OLIG2 Gene on OLIG2 Transcription and White Matter Integrity.
    Komatsu H, Takeuchi H, Kikuchi Y, Ono C, Yu Z, Iizuka K, Takano Y, Kakuto Y, Funakoshi S, Ono T, Ito J, Kunii Y, Hino M, Nagaoka A, Iwasaki Y, Yamamori H, Yasuda Y, Fujimoto M, Azechi H, Kudo N, Hashimoto R, Yabe H, Yoshida M, Saito Y, Kakita A, Fuse N, Kawashima R, Taki Y, Tomita H., Free PMC Article

    10/30/2021
    OLIG2 maintenance is not essential for diffuse intrinsic pontine glioma cell line growth but regulates tumor phenotypes.

    OLIG2 maintenance is not essential for diffuse intrinsic pontine glioma cell line growth but regulates tumor phenotypes.
    Liao Y, Luo Z, Deng Y, Zhang F, Rao R, Wang J, Xu L, Kumar SS, Sengupta S, DeWire-Schottmiller M, Berry K, Garrett M, Fouladi M, Drissi R, Lu QR., Free PMC Article

    09/18/2021
    Pediatric Soft Tissue Tumors With BCOR ITD Express EGFR but Not OLIG2.

    Pediatric Soft Tissue Tumors With BCOR ITD Express EGFR but Not OLIG2.
    Salgado CM, Zin A, Garrido M, Kletskaya I, DeVito R, Reyes-Múgica M, Bisogno G, Donofrio V, Alaggio R.

    09/11/2021
    Rapid induction of gliogenesis in OLIG2 and NKX2.2-expressing progenitors-derived spheroids.

    Rapid induction of gliogenesis in OLIG2 and NKX2.2-expressing progenitors-derived spheroids.
    Yun W, Kim IY, Song G, You S., Free PMC Article

    09/4/2021
    Association of rs1059004 polymorphism in the OLIG2 locus with whole-brain functional connectivity in first-episode schizophrenia.

    Association of rs1059004 polymorphism in the OLIG2 locus with whole-brain functional connectivity in first-episode schizophrenia.
    Cai S, Lv Y, Huang K, Zhang W, Kang Y, Huang L, Wang J.

    05/8/2021
    Prognostic impact of glioblastoma stem cell markers OLIG2 and CCND2.

    Prognostic impact of glioblastoma stem cell markers OLIG2 and CCND2.
    Bouchart C, Trépant AL, Hein M, Van Gestel D, Demetter P., Free PMC Article

    05/1/2021
    Association of rs1059004 polymorphism in the OLIG2 locus with functional brain network in first-episode negative schizophrenia.

    Association of rs1059004 polymorphism in the OLIG2 locus with functional brain network in first-episode negative schizophrenia.
    Lv Y, Wu S, Lin Y, Wang X, Wang J, Cai S, Huang L.

    12/19/2020
    Variants of the OLIG2 Gene are Associated with Cerebral Palsy in Chinese Han Infants with Hypoxic-Ischemic Encephalopathy.

    Variants of the OLIG2 Gene are Associated with Cerebral Palsy in Chinese Han Infants with Hypoxic-Ischemic Encephalopathy.
    Sun L, Xia L, Wang M, Zhu D, Wang Y, Bi D, Song J, Ma C, Gao C, Zhang X, Sun Y, Wang X, Zhu C, Xing Q.

    10/3/2020
    altered OLIG2 expression may underlie neurodevelopmental abnormalities and cognitive defects in Down syndrome patients

    OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome.
    Xu R, Brawner AT, Li S, Liu JJ, Kim H, Xue H, Pang ZP, Kim WY, Hart RP, Liu Y, Jiang P., Free PMC Article

    07/25/2020
    Our findings identify OLIG2 expression as a unique manifestation of a neurodevelopmental gene expression signature driven by the oncogenic fusion protein characteristic of alveolar rhabdomyosarcoma

    OLIG2 is a marker of the fusion protein-driven neurodevelopmental transcriptional signature in alveolar rhabdomyosarcoma.
    Raghavan SS, Mooney KL, Folpe AL, Charville GW.

    06/13/2020
    Positive reaction with OLIG2 (6 tumours) was always associated with the presence of PAX3/7-FOXO1 rearrangement

    OLIG2 is a novel immunohistochemical marker associated with the presence of PAX3/7-FOXO1 translocation in rhabdomyosarcomas.
    Kaleta M, Wakulińska A, Karkucińska-Więckowska A, Dembowska-Bagińska B, Grajkowska W, Pronicki M, Łastowska M., Free PMC Article

    03/14/2020
    The OLIG2 gene may be involved in obsessive-compulsive disorder

    OLIG2 gene polymorphisms are associated with nasty, unpleasant and uncontrollable thoughts in obsessive-compulsive disorder.
    Vieira-Fonseca T, Fontenelle LF, Kohlrausch FB.

    02/8/2020
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