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    THORLNC testis associated oncogenic lncRNA [ Homo sapiens (human) ]

    Gene ID: 100506797, updated on 10-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The lncRNA THOR interacts with and stabilizes hnRNPD to promote cell proliferation and metastasis in breast cancer.

    The lncRNA THOR interacts with and stabilizes hnRNPD to promote cell proliferation and metastasis in breast cancer.
    Hu H, Zhang H, Xing Y, Zhou Y, Chen J, Li C, Xu J, Guo Y, Wang J, He Q, Liu X, Sheng J, Song E, Wu Y, Huang H.

    12/10/2022
    LncRNA THOR promotes endometrial cancer progression through the AKT and ERK signaling pathways.

    LncRNA THOR promotes endometrial cancer progression through the AKT and ERK signaling pathways.
    Zhang HQ, Li T, Li C, Hu HT, Zhu SM, Lu JQ, Chen XJ, Huang HF, Wu YT.

    10/8/2022
    Carboxymethylated chitosan alleviated oxidative stress injury in retinal ganglion cells via IncRNA-THOR/IGF2BP1 axis.

    Carboxymethylated chitosan alleviated oxidative stress injury in retinal ganglion cells via IncRNA-THOR/IGF2BP1 axis.
    Wu X, Liu Y, Ji Y.

    03/5/2022
    Long Non-Coding RNA THOR Enhances the Stem Cell-Like Traits of Triple-Negative Breast Cancer Cells Through Activating beta-Catenin Signaling.

    Long Non-Coding RNA THOR Enhances the Stem Cell-Like Traits of Triple-Negative Breast Cancer Cells Through Activating β-Catenin Signaling.
    Wang B, Ye Q, Zou C., Free PMC Article

    05/8/2021
    A novel N6-methyladenosine (m6A)-dependent fate decision for the lncRNA THOR.

    A novel N6-methyladenosine (m6A)-dependent fate decision for the lncRNA THOR.
    Liu H, Xu Y, Yao B, Sui T, Lai L, Li Z., Free PMC Article

    03/28/2021
    Lnc-THOR silencing inhibits human glioma cell survival by activating MAGEA6-AMPK signaling.

    Lnc-THOR silencing inhibits human glioma cell survival by activating MAGEA6-AMPK signaling.
    Xue J, Zhong S, Sun BM, Sun QF, Hu LY, Pan SJ., Free PMC Article

    08/29/2020
    THOR mediated IGF2 expression via interacting with IGF2BP1, and affected the downstream MEK-ERK signaling pathway to regulate tongue squamous cell carcinomas cells proliferation.

    LncRNA THOR promotes tongue squamous cell carcinomas by stabilizing IGF2BP1 downstream targets.
    Yang H, Fu G, Liu F, Hu C, Lin J, Tan Z, Fu Y, Ji F, Cao M.

    02/29/2020
    THOR expression promotes renal cell carcinoma cell growth in vitro and in vivo.

    LncRNA THOR promotes human renal cell carcinoma cell growth.
    Ye XT, Huang H, Huang WP, Hu WL.

    05/18/2019
    THOR could potentiate the stemness of gastric cancer cells via directly binding to SOX9 3'UTR.

    LncRNA THOR increases the stemness of gastric cancer cells via enhancing SOX9 mRNA stability.
    Song H, Xu Y, Shi L, Xu T, Fan R, Cao M, Xu W, Song J.

    03/16/2019
    lncRNA THOR is up-regulated in retinoblastoma, and its over-expression significantly enhances the malignant phenotype transformation of retinoblastoma cells by up-regulating c-myc and TGF2BP1 expression.

    LncRNA THOR acts as a retinoblastoma promoter through enhancing the combination of c-myc mRNA and IGF2BP1 protein.
    Shang Y.

    12/22/2018
    results demonstrate that lncRNA THOR could attenuate cisplatin sensitivity of NPC cells by enhancing cells stemness through promoting YAP transcriptional activity

    LncRNA THOR attenuates cisplatin sensitivity of nasopharyngeal carcinoma cells via enhancing cells stemness.
    Gao L, Cheng XL, Cao H.

    12/1/2018
    Data demonstrated that THOR expression is upregulated in hepatocellular carcinoma (HCC) tissues, and THOR siRNA silencing suppresses the growth and metastasis of HCC cells. Moreover, THOR promoted HCC cell progression by activating PTEN/AKT signaling in vitro.

    Long non-coding RNA THOR promotes cell proliferation and metastasis in hepatocellular carcinoma.
    Cheng Z, Lei Z, Yang P, Si A, Xiang D, Zhou J, Hüser N.

    10/27/2018
    Lnc-THOR expression is essential for human osteosarcoma cell growth.

    Long non-coding RNA THOR promotes human osteosarcoma cell growth in vitro and in vivo.
    Chen W, Chen M, Xu Y, Chen X, Zhou P, Zhao X, Pang F, Liang W.

    10/13/2018
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