| Repression of Smad4 by MicroRNA-1285 moderates TGF-beta-induced epithelial-mesenchymal transition in proliferative vitreoretinopathy. | Repression of Smad4 by MicroRNA-1285 moderates TGF-β-induced epithelial-mesenchymal transition in proliferative vitreoretinopathy.
Pao SI, Lin LT, Chen YH, Chen CL, Chen JT., Free PMC Article | 12/4/2021 |
| Circular RNA hsa_circ_0000376 Participates in Tumorigenesis of Breast Cancer by Targeting miR-1285-3p. | Circular RNA hsa_circ_0000376 Participates in Tumorigenesis of Breast Cancer by Targeting miR-1285-3p.
Peng Z, Xu B, Jin F., Free PMC Article | 01/9/2021 |
| Data showed the tumor-suppressive role of miR-1285 and detailed its mechanism of action in breast cancer. Its overexpression significantly inhibited cell proliferation in breast cancer cells regardless of the tumor subtype. Also, miR-1285 was found to regulate TMEM194A expression by binding to its 3'-UTR. | MiR-1285-5p/TMEM194A axis affects cell proliferation in breast cancer.
Hironaka-Mitsuhashi A, Otsuka K, Gailhouste L, Sanchez Calle A, Kumazaki M, Yamamoto Y, Fujiwara Y, Ochiya T., Free PMC Article | 02/22/2020 |
| MiR-1285-3p was down regulated in osteosarcoma tissues and cell lines and reduction of miR-1285-3p expression predicted a poor overall survival of osteosarcoma patients. Ectopic expression of miR-1285-3p inhibited osteosarcoma cell proliferation, colony formation and invasion. | miR-1285-3p is a potential prognostic marker in human osteosarcoma and functions as a tumor suppressor by targeting YAP1.
Hu XH, Dai J, Shang HL, Zhao ZX, Hao YD. | 01/25/2020 |
| Methylation dependent microRNA 1285-5p and sterol carrier proteins 2 in type 2 diabetes mellitus | Methylation dependent microRNA 1285-5p and sterol carrier proteins 2 in type 2 diabetes mellitus.
Bai L, Li J, Panagal M, M B, Sekar D. | 01/11/2020 |
| miR-1285 suppressed cell proliferation as well as increased the sensitivity of pancreatic ductal adenocarcinoma cells to gemcitabine; miR-1285 inhibited pancreatic cancer cell migration and invasion | MicroRNA-1285 inhibits malignant biological behaviors of human pancreatic cancer cells by negative regulation of YAP1.
Huang H, Xiong G, Shen P, Cao Z, Zheng L, Zhang T, Zhao Y. | 04/27/2019 |
| The combination of plasma miR-324-3p and miR-1285 could further improve the diagnostic accuracy of lung squamous cell carcinoma (LSCC). | Plasma miR-324-3p and miR-1285 as diagnostic and prognostic biomarkers for early stage lung squamous cell carcinoma.
Gao X, Wang Y, Zhao H, Wei F, Zhang X, Su Y, Wang C, Li H, Ren X., Free PMC Article | 02/10/2018 |
| our data suggest that miR-1285-5p functions as a tumor promoter in the development of non-small-cell lung carcinoma by targeting Smad4 and CDH1, indicating a novel therapeutic strategy for non-small-cell lung carcinoma patients. | MicroRNA-1285-5p influences the proliferation and metastasis of non-small-cell lung carcinoma cells via downregulating CDH1 and Smad4.
Zhou S, Zhang Z, Zheng P, Zhao W, Han N. | 07/22/2017 |
| Data show that four cardiac fibroblast-derived microRNAS miR-660-3p, miR-665, miR-1285-3p and miR-4491 were found significantly upregulated in heart and plasma during heart failure. | Identification of cardiac-related circulating microRNA profile in human chronic heart failure.
Li H, Fan J, Yin Z, Wang F, Chen C, Wang DW., Free PMC Article | 11/5/2016 |
| Human miR-1285-3p could directly repress JUN oncogene expression in hepatocellular carcinoma cells. | miR-1285-3p acts as a potential tumor suppressor miRNA via downregulating JUN expression in hepatocellular carcinoma.
Liu J, Yan J, Zhou C, Ma Q, Jin Q, Yang Z. | 05/16/2015 |
| miR-1285 modulates a novel molecular target and provides new insights into potential mechanisms of renal cell carcinoma oncogenesis. | Tumor suppressive microRNA-1285 regulates novel molecular targets: aberrant expression and functional significance in renal cell carcinoma.
Hidaka H, Seki N, Yoshino H, Yamasaki T, Yamada Y, Nohata N, Fuse M, Nakagawa M, Enokida H., Free PMC Article | 07/7/2012 |