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    Shisa3 shisa family member 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498356, updated on 9-Dec-2024

    Summary

    Official Symbol
    Shisa3provided by RGD
    Official Full Name
    shisa family member 3provided by RGD
    Primary source
    RGD:1565710
    See related
    EnsemblRapid:ENSRNOG00000025670 AllianceGenome:RGD:1565710
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1565710
    Summary
    Predicted to act upstream of or within negative regulation of canonical Wnt signaling pathway. Predicted to be located in membrane. Orthologous to human SHISA3 (shisa family member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 23.7), Brain (RPKM 16.9) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Shisa3 in Genome Data Viewer
    Location:
    14p11
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (40917563..40922135, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (40563672..40568244, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (42216653..42221225, complement)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120096602 Neighboring gene ATPase phospholipid transporting 8A1 Neighboring gene uncharacterized LOC134481745 Neighboring gene uncharacterized LOC120096535

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    protein shisa-3 homolog
    Names
    shisa homolog 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109087.2NP_001102557.1  protein shisa-3 homolog precursor

      See identical proteins and their annotated locations for NP_001102557.1

      Status: PROVISIONAL

      Source sequence(s)
      BC168960
      UniProtKB/TrEMBL
      B5DF81, F7FMB1
      Related
      ENSRNOP00000033959.3, ENSRNOT00000036103.5
      Conserved Domains (1) summary
      pfam13908
      Location:25161
      Shisa; Wnt and FGF inhibitory regulator

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      40917563..40922135 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)