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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_042870.2 RefSeqGene
- Range
-
5000..12503
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001272101.2 → NP_001259030.1 matrix metalloproteinase-19 isoform 3 preproprotein
See identical proteins and their annotated locations for NP_001259030.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) contains multiple differences in the coding region, compared to variant 1, one of which results in a frameshift. The encoded isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1.
- Source sequence(s)
-
AC023055
- Consensus CDS
-
CCDS61146.1
- UniProtKB/Swiss-Prot
-
Q99542
- Related
- ENSP00000386625.3, ENST00000409200.7
- Conserved Domains (3) summary
-
- pfam00413
Location:103 → 174
- Peptidase_M10; Matrixin
- pfam01471
Location:31 → 80
- PG_binding_1; Putative peptidoglycan binding domain
- cl00064
Location:103 → 174
- ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...
-
NM_001414375.1 → NP_001401304.1 matrix metalloproteinase-19 isoform 4 preproprotein
Status: REVIEWED
- Source sequence(s)
-
AC023055
- UniProtKB/TrEMBL
-
F8W1C3
-
NM_002429.6 → NP_002420.1 matrix metalloproteinase-19 isoform 1 preproprotein
See identical proteins and their annotated locations for NP_002420.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1, also known as rasi-1).
- Source sequence(s)
-
AC023055
- Consensus CDS
-
CCDS8895.1
- UniProtKB/Swiss-Prot
- B4E030, O15278, O95606, Q99542, Q99580
- UniProtKB/TrEMBL
-
F8W1C3
- Related
- ENSP00000313437.4, ENST00000322569.9
- Conserved Domains (3) summary
-
- cd00094
Location:286 → 472
- HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
- cd04278
Location:103 → 256
- ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
- pfam01471
Location:31 → 80
- PG_binding_1; Putative peptidoglycan binding domain
RNA
-
NR_073606.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) uses two alternate splice sites at internal exons, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC023055
-
NR_182299.1 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC023055
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000012.12 Reference GRCh38.p14 Primary Assembly
- Range
-
55835433..55842936 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047428863.1 → XP_047284819.1 matrix metalloproteinase-19 isoform X1
- UniProtKB/TrEMBL
-
F8W1C3
Alternate T2T-CHM13v2.0
Genomic
-
NC_060936.1 Alternate T2T-CHM13v2.0
- Range
-
55802080..55809587 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054372076.1 → XP_054228051.1 matrix metalloproteinase-19 isoform X1
- UniProtKB/TrEMBL
-
F8W1C3
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_001032360.1: Suppressed sequence
- Description
- NM_001032360.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
-
NM_022790.1: Suppressed sequence
- Description
- NM_022790.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
-
NM_022792.2: Suppressed sequence
- Description
- NM_022792.2: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.