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    CG13442 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37349, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG13442provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034546
    Locus tag
    Dmel_CG13442
    See related
    AllianceGenome:FB:FBgn0034546
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG13442
    Summary
    Predicted to enable ubiquitin protein ligase activity and zinc ion binding activity. Predicted to be involved in protein polyubiquitination. Predicted to be located in endosome and lysosome. Is expressed in adult head. Orthologous to human MARCHF3 (membrane associated ring-CH-type finger 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG13442 in Genome Data Viewer
    Location:
    57B1-57B1; 2-92 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20727829..20730610, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16615334..16618115, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene defective proboscis extension response 1 Neighboring gene long non-coding RNA:CR44660 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Large-scale RNAi screen identified Dhpr as a regulator of mitochondrial morphology and tissue homeostasis. Zhou J, et al. Sci Adv, 2019 Sep. PMID 31555733, Free PMC Article
    2. Comprehensively surveying structure and function of RING domains from Drosophila melanogaster. Ying M, et al. PLoS One, 2011. PMID 21912646, Free PMC Article
    3. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article
    4. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
    5. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables ubiquitin-protein transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin-protein transferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein polyubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in endosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in lysosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG13442-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      20727829..20730610 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137667.4 → NP_611511.3  uncharacterized protein Dmel_CG13442 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611511.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBY4, Q8MZF9
      Related
      FBpp0085553
      Conserved Domains (2) summary
      smart00744
      Location:166 → 213
      RINGv; The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins
      cl07893
      Location:36 → 151
      AmyAc_family; Alpha amylase catalytic domain family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1ZBY4 A1ZBY4
    Q8MZF9 Q8MZF9

    Gene LinkOut

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