U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    TAS2R60 taste 2 receptor member 60 [ Homo sapiens (human) ]

    Gene ID: 338398, updated on 9-Dec-2024

    Summary

    Official Symbol
    TAS2R60provided by HGNC
    Official Full Name
    taste 2 receptor member 60provided by HGNC
    Primary source
    HGNC:HGNC:20639
    See related
    Ensembl:ENSG00000185899 MIM:613968; AllianceGenome:HGNC:20639
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    T2R56; T2R60
    Summary
    This gene encodes a member of the bitter taste receptor family which belong to the G protein-coupled receptor superfamily and are predominantly expressed in taste receptor cells of the tongue and palate epithelia. This intronless taste receptor gene encodes a seven-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered together with eight other taste receptor genes on chromosome 7. [provided by RefSeq, Jul 2017]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See TAS2R60 in Genome Data Viewer
    Location:
    7q35
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (143443453..143444409)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (144798817..144799773)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (143140546..143141502)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:143088659-143089259 Neighboring gene Sharpr-MPRA regulatory region 10434 Neighboring gene Sharpr-MPRA regulatory region 2529 Neighboring gene EPH receptor A1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:143101922-143102436 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:143106021-143106633 Neighboring gene EPHA1 antisense RNA 1 Neighboring gene Sharpr-MPRA regulatory region 12322 Neighboring gene taste 2 receptor member 62 pseudogene Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr7:143169186-143170385 Neighboring gene taste 2 receptor member 41 Neighboring gene olfactory receptor family 2 subfamily R member 1, pseudogene

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    taste receptor type 2 member 60
    Names
    taste receptor type 2 member 56
    taste receptor, type 2, member 60

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177437.1NP_803186.1  taste receptor type 2 member 60

      See identical proteins and their annotated locations for NP_803186.1

      Status: REVIEWED

      Source sequence(s)
      AY114094
      Consensus CDS
      CCDS5885.1
      UniProtKB/Swiss-Prot
      A4D2G8, P59551, Q645W8, Q7RTR7
      UniProtKB/TrEMBL
      Q50KC8
      Related
      ENSP00000327724.1, ENST00000332690.1
      Conserved Domains (1) summary
      cd15018
      Location:31308
      7tm_TAS2R41-like; mammalian taste receptor 2, subtype 41, member of the seven-transmembrane G protein-coupled receptor superfamily

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

      Range
      143443453..143444409
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_018654714.1 Reference GRCh38.p14 PATCHES

      Range
      62817..63773
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060931.1 Alternate T2T-CHM13v2.0

      Range
      144798817..144799773
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)