U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Fastkd1 FAST kinase domains 1 [ Mus musculus (house mouse) ]

    Gene ID: 320720, updated on 9-Dec-2024

    Summary

    Official Symbol
    Fastkd1provided by MGI
    Official Full Name
    FAST kinase domains 1provided by MGI
    Primary source
    MGI:MGI:2444596
    See related
    Ensembl:ENSMUSG00000027086 AllianceGenome:MGI:2444596
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA1800; 5330408N05Rik
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in mitochondrial RNA metabolic process; mitochondrial RNA processing; and regulation of mitochondrial mRNA stability. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial matrix and ribonucleoprotein granule. Is expressed in central nervous system; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human FASTKD1 (FAST kinase domains 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 4.3), CNS E11.5 (RPKM 3.6) and 27 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Fastkd1 in Genome Data Viewer
    Location:
    2 C2; 2 40.93 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (69517159..69543875, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (69686820..69712606, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene Bardet-Biedl syndrome 5 Neighboring gene kelch-like 41 Neighboring gene STARR-seq mESC enhancer starr_04743 Neighboring gene STARR-positive B cell enhancer ABC_E10110 Neighboring gene peptidyl-prolyl isomerase G (cyclophilin G) Neighboring gene STARR-positive B cell enhancer mm9_chr2:69582878-69583179 Neighboring gene 60S ribosomal protein L13-like Neighboring gene cilia and flagella associated protein 210 Neighboring gene STARR-seq mESC enhancer starr_04744

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • KIAA1800

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial RNA metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitochondrial RNA metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in mitochondrial RNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of mitochondrial mRNA stability IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of mitochondrial mRNA stability ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of mitochondrial mRNA stability ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    is_active_in ribonucleoprotein granule IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    FAST kinase domain-containing protein 1, mitochondrial

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177244.3NP_796218.2  FAST kinase domain-containing protein 1, mitochondrial

      See identical proteins and their annotated locations for NP_796218.2

      Status: PROVISIONAL

      Source sequence(s)
      BC075689
      Consensus CDS
      CCDS16096.1
      UniProtKB/Swiss-Prot
      A2AR00, B0R0D3, Q5DTU7, Q6DI86, Q6IS39, Q8BSV8, Q8C429, Q8R1N6
      Related
      ENSMUSP00000072896.7, ENSMUST00000073152.13
      Conserved Domains (3) summary
      smart00952
      Location:763821
      RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
      pfam06743
      Location:560628
      FAST_1; FAST kinase-like protein, subdomain 1
      pfam08368
      Location:648729
      FAST_2; FAST kinase-like protein, subdomain 2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      69517159..69543875 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036162311.1XP_036018204.1  FAST kinase domain-containing protein 1, mitochondrial isoform X1

      Conserved Domains (3) summary
      smart00952
      Location:635693
      RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
      pfam06743
      Location:432500
      FAST_1; FAST kinase-like protein, subdomain 1
      pfam08368
      Location:519601
      FAST_2; FAST kinase-like protein, subdomain 2

    RNA

    1. XR_004940626.1 RNA Sequence