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    Vha36-3 Vacuolar H[+] ATPase 36kD subunit 3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31235, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Vha36-3provided by FlyBase
    Official Full Name
    Vacuolar H[+] ATPase 36kD subunit 3provided by FlyBase
    Primary source
    FLYBASE:FBgn0040377
    Locus tag
    Dmel_CG8310
    See related
    AllianceGenome:FB:FBgn0040377
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8310; Dmel\CG8310; EG:BACR25B3.4; vha36-3
    Summary
    Predicted to contribute to proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in proton transmembrane transport. Predicted to be part of proton-transporting V-type ATPase complex. Is expressed in adult head. Orthologous to human ATP6V1D (ATPase H+ transporting V1 subunit D). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Vha36-3 in Genome Data Viewer
    Location:
    3A6-3A6; 1-1 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2579091..2580560, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (2473124..2474593, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene terribly reduced optic lobes Neighboring gene mir-4955 stem loop Neighboring gene Pigment-dispersing factor receptor Neighboring gene Arylalkylamine N-acetyltransferase-like 7 Neighboring gene uncharacterized protein Neighboring gene will die slowly

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington disease. Greco TM, et al. Cell Syst, 2022 Apr 20. PMID 35148841, Free PMC Article
    2. A G protein-coupled receptor, groom-of-PDF, is required for PDF neuron action in circadian behavior. Lear BC, et al. Neuron, 2005 Oct 20. PMID 16242403
    3. Recent origins of sperm genes in Drosophila. Dorus S, et al. Mol Biol Evol, 2008 Oct. PMID 18653731, Free PMC Article
    4. Genome-wide survey of V-ATPase genes in Drosophila reveals a conserved renal phenotype for lethal alleles. Allan AK, et al. Physiol Genomics, 2005 Jul 14. PMID 15855386
    5. Endolysosomal trafficking controls yolk granule biogenesis in vitellogenic Drosophila oocytes. Yu Y, et al. PLoS Genet, 2024 Feb. PMID 38315726, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    contributes_to proton-transporting ATPase activity, rotational mechanism IC
    Inferred by Curator
    more info
    		  
    enables proton-transporting ATPase activity, rotational mechanism IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proton transmembrane transport IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of proton-transporting V-type ATPase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of proton-transporting V-type ATPase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    vacuolar H[+] ATPase 36kD subunit 3
    Names
    CG8310-PB
    CG8310-PC
    Vha36-3-PB
    Vha36-3-PC
    vacuolar H[+] ATPase subunit 36-3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      2579091..2580560 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001297899.1 → NP_001284828.1  vacuolar H[+] ATPase 36kD subunit 3, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284828.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9I7X1, Q9NEF6
      UniProtKB/TrEMBL
      X2JE14
      Conserved Domains (1) summary
      pfam01813
      Location:17 → 206
      ATP-synt_D; ATP synthase subunit D

    2. NM_130652.4 → NP_570008.1  vacuolar H[+] ATPase 36kD subunit 3, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_570008.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9I7X1, Q9NEF6
      UniProtKB/TrEMBL
      X2JE14
      Related
      FBpp0308493
      Conserved Domains (1) summary
      pfam01813
      Location:17 → 206
      ATP-synt_D; ATP synthase subunit D
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9NEF6.1 Q9NEF6
    X2JE14 X2JE14

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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