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    Nyap1 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 304376, updated on 9-Dec-2024

    Summary

    Symbol
    Nyap1provided by RGD
    Full Name
    neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1provided by RGD
    Primary source
    RGD:1310964
    See related
    EnsemblRapid:ENSRNOG00000024641 AllianceGenome:RGD:1310964
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310964
    Summary
    Predicted to be involved in neuron projection morphogenesis and phosphatidylinositol 3-kinase/protein kinase B signal transduction. Orthologous to human NYAP1 (neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 61.0), Kidney (RPKM 14.0) and 7 other tissues See more
    Orthologs
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    Genomic context

    See Nyap1 in Genome Data Viewer
    Location:
    12q12
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (24591574..24604417)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (18956192..18967624)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (22025186..22037428)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134481171 Neighboring gene sperm acrosome developmental regulator Neighboring gene TSC22 domain family, member 4 Neighboring gene enoyl CoA hydratase domain containing 2, pseudogene 1 Neighboring gene ArfGAP with FG repeats 2 Neighboring gene insulin receptor substrate 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1
    Names
    neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107132.1NP_001100602.1  neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1

      See identical proteins and their annotated locations for NP_001100602.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473973
      UniProtKB/TrEMBL
      A6J004
      Conserved Domains (2) summary
      pfam15439
      Location:15413
      NYAP_N; Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter
      pfam15452
      Location:574835
      NYAP_C; Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      24591574..24604417
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006249144.5XP_006249206.1  neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1 isoform X1

      See identical proteins and their annotated locations for XP_006249206.1

      UniProtKB/TrEMBL
      D3ZDP7
      Related
      ENSRNOP00000031656.5, ENSRNOT00000029041.6
      Conserved Domains (2) summary
      pfam15439
      Location:15413
      NYAP_N; Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter
      pfam15452
      Location:574836
      NYAP_C; Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter
    2. XM_017598325.3XP_017453814.1  neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1 isoform X1

      UniProtKB/TrEMBL
      D3ZDP7
      Conserved Domains (2) summary
      pfam15439
      Location:15413
      NYAP_N; Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter
      pfam15452
      Location:574836
      NYAP_C; Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter
    3. XM_006249147.5XP_006249209.1  neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1 isoform X1

      See identical proteins and their annotated locations for XP_006249209.1

      UniProtKB/TrEMBL
      D3ZDP7
      Conserved Domains (2) summary
      pfam15439
      Location:15413
      NYAP_N; Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter
      pfam15452
      Location:574836
      NYAP_C; Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter
    4. XM_006249145.5XP_006249207.1  neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1 isoform X1

      See identical proteins and their annotated locations for XP_006249207.1

      UniProtKB/TrEMBL
      D3ZDP7
      Conserved Domains (2) summary
      pfam15439
      Location:15413
      NYAP_N; Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter
      pfam15452
      Location:574836
      NYAP_C; Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter