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    VEL1 vernalization5/VIN3-like protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829143, updated on 18-Sep-2024

    Summary

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    Official Symbol
    VEL1
    Official Full Name
    vernalization5/VIN3-like protein
    Primary source
    TAIR:AT4G30200
    Locus tag
    AT4G30200
    See related
    Araport:AT4G30200
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    vernalization5/VIN3-like; vernalization5/VIN3-like 1; VIL2; VIN3-Like 2
    Summary
    Encodes a protein with similarity to VRN5 and VIN3.Contains both a fibronectin III and PHD finger domain. VEL1 is a part of a polycomb repressive complex (PRC2) that is involved in epigenetic silencing of the FLC flowering locus.
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    Genomic context

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    See VEL1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Sequence:
    Chromosome: 4; NC_003075.7 (14786532..14790501, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene H[+]-ATPase 2 Neighboring gene P450 reductase 2 Neighboring gene small nuclear ribonucleoprotein F

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Plant Homeo Domain finger protein, VIN3-LIKE 2, is necessary for photoperiod-mediated epigenetic regulation of the floral repressor, MAF5. Kim DH, et al. Proc Natl Acad Sci U S A, 2010 Sep 28. PMID 20837520, Free PMC Article
    2. A PHD finger protein involved in both the vernalization and photoperiod pathways in Arabidopsis. Sung S, et al. Genes Dev, 2006 Dec 1. PMID 17114575, Free PMC Article
    3. A PHD-polycomb repressive complex 2 triggers the epigenetic silencing of FLC during vernalization. De Lucia F, et al. Proc Natl Acad Sci U S A, 2008 Nov 4. PMID 18854416, Free PMC Article
    4. Arabidopsis MSI1 connects LHP1 to PRC2 complexes. Derkacheva M, et al. EMBO J, 2013 Jul 17. PMID 23778966, Free PMC Article
    5. Proteome-wide screens for small ubiquitin-like modifier (SUMO) substrates identify Arabidopsis proteins implicated in diverse biological processes. Elrouby N, et al. Proc Natl Acad Sci U S A, 2010 Oct 5. PMID 20855607, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. the repression of MAF5 by VIL2 provides a mechanism to promote flowering in noninductive photoperiods, which contributes to the facultative nature of the Arabidopsis photoperiodic response.
      Title: The Plant Homeo Domain finger protein, VIN3-LIKE 2, is necessary for photoperiod-mediated epigenetic regulation of the floral repressor, MAF5.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001203942.1
    NM_119166.5
    NM_179140.2
    NM_202910.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables identical protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables methylated histone binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in circadian regulation of gene expression IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in negative regulation of gene expression, epigenetic IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of short-day photoperiodism, flowering IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within vegetative to reproductive phase transition of meristem IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    involved_in vernalization response IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of PcG protein complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of chromatin silencing complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    vernalization5/VIN3-like protein
    NP_001190871.1
    • vernalization5/VIN3-like (VEL1); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: vegetative to reproductive phase transition of meristem; LOCATED IN: PcG protein complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1423, plant (InterPro:IPR004082), Fibronectin, type III-like fold (InterPro:IPR008957), Fibronectin, type III (InterPro:IPR003961); BEST Arabidopsis thaliana protein match is: Fibronectin type III domain-containing protein (TAIR:AT5G57380.1).
    NP_194749.1
    • vernalization5/VIN3-like (VEL1); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1423, plant (InterPro:IPR004082), Fibronectin, type III-like fold (InterPro:IPR008957), Fibronectin, type III (InterPro:IPR003961); BEST Arabidopsis thaliana protein match is: Fibronectin type III domain-containing protein (TAIR:AT5G57380.1); Has 283 Blast hits to 258 proteins in 40 species: Archae - 0; Bacteria - 10; Metazoa - 3; Fungi - 23; Plants - 240; Viruses - 0; Other Eukaryotes - 7 (source: NCBI BLink).
    NP_849471.1
    • vernalization5/VIN3-like (VEL1); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1423, plant (InterPro:IPR004082), Fibronectin, type III-like fold (InterPro:IPR008957), Fibronectin, type III (InterPro:IPR003961); BEST Arabidopsis thaliana protein match is: Fibronectin type III domain-containing protein (TAIR:AT5G57380.1); Has 270 Blast hits to 250 proteins in 39 species: Archae - 0; Bacteria - 2; Metazoa - 8; Fungi - 14; Plants - 239; Viruses - 0; Other Eukaryotes - 7 (source: NCBI BLink).
    NP_974639.1
    • vernalization5/VIN3-like (VEL1); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1423, plant (InterPro:IPR004082), Fibronectin, type III-like fold (InterPro:IPR008957), Fibronectin, type III (InterPro:IPR003961); BEST Arabidopsis thaliana protein match is: Fibronectin type III domain-containing protein (TAIR:AT5G57380.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      14786532..14790501 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_202910.4 → NP_974639.1  vernalization5/VIN3-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974639.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V2Q4
      Conserved Domains (2) summary
      smart00060
      Location:356 → 433
      FN3; Fibronectin type 3 domain
      pfam07227
      Location:146 → 264
      PHD_Oberon; PHD - plant homeodomain finger protein

    2. NM_119166.5 → NP_194749.1  vernalization5/VIN3-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194749.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DFL9, F4JPJ8, F4JPK1, Q2QJG1, Q8GUH6, Q9SUM4
      UniProtKB/TrEMBL
      A0A178V1S1, A0A5S9XX75
      Conserved Domains (2) summary
      smart00060
      Location:368 → 445
      FN3; Fibronectin type 3 domain
      pfam07227
      Location:146 → 264
      PHD_Oberon; PHD - plant homeodomain finger protein

    3. NM_179140.2 → NP_849471.1  vernalization5/VIN3-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849471.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V2Q4
      Conserved Domains (2) summary
      smart00060
      Location:339 → 416
      FN3; Fibronectin type 3 domain
      pfam07227
      Location:129 → 247
      PHD_Oberon; PHD - plant homeodomain finger protein

    4. NM_001203942.1 → NP_001190871.1  vernalization5/VIN3-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190871.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V1S1, A0A5S9XX75
      Conserved Domains (2) summary
      smart00060
      Location:368 → 445
      FN3; Fibronectin type 3 domain
      pfam07227
      Location:146 → 264
      PHD_Oberon; PHD - plant homeodomain finger protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SUM4.1

    Gene LinkOut

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