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    ADF7 actin depolymerizing factor 7 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828664, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ADF7
    Official Full Name
    actin depolymerizing factor 7
    Primary source
    TAIR:AT4G25590
    Locus tag
    AT4G25590
    See related
    Araport:AT4G25590
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    actin depolymerizing factor 7; M7J2.40; M7J2_40
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    Genomic context

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    See ADF7 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    3
    Sequence:
    Chromosome: 4; NC_003075.7 (13058936..13060250, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene CAP160 protein Neighboring gene tRNA-Ser Neighboring gene Oxoglutarate/iron-dependent oxygenase Neighboring gene C2H2-like zinc finger protein Neighboring gene hydroxyproline-rich glycoprotein family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis actin-depolymerizing factor7 severs actin filaments and regulates actin cable turnover to promote normal pollen tube growth. Zheng Y, et al. Plant Cell, 2013 Sep. PMID 24058157, Free PMC Article
    2. Differential sensitivity of ADF isovariants to a pH gradient promotes pollen tube growth. Wang J, et al. J Cell Biol, 2023 Nov 6. PMID 37610419, Free PMC Article
    3. Actin depolymerizing factors ADF7 and ADF10 play distinct roles during pollen development and pollen tube growth. Daher FB, et al. Plant Signal Behav, 2012 Jul. PMID 22751315, Free PMC Article
    4. Spatial and temporal expression of actin depolymerizing factors ADF7 and ADF10 during male gametophyte development in Arabidopsis thaliana. Bou Daher F, et al. Plant Cell Physiol, 2011 Jul. PMID 21632657
    5. Plant Actin-Depolymerizing Factors Possess Opposing Biochemical Properties Arising from Key Amino Acid Changes throughout Evolution. Nan Q, et al. Plant Cell, 2017 Feb. PMID 28123105, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Differential sensitivity of ADF isovariants to a pH gradient promotes pollen tube growth.
      Title: Differential sensitivity of ADF isovariants to a pH gradient promotes pollen tube growth.
    2. ADF7 evolved to promote turnover of longitudinal actin cables by severing actin filaments in pollen tubes.
      Title: Arabidopsis actin-depolymerizing factor7 severs actin filaments and regulates actin cable turnover to promote normal pollen tube growth.
    3. ADF7 and ADF10 play distinct roles during pollen development and pollen tube growth.
      Title: Actin depolymerizing factors ADF7 and ADF10 play distinct roles during pollen development and pollen tube growth.
    4. ADF7 and ADF10 were differentially expressed with the ADF7 signal appearing in the microspore stage and that of ADF10 only during the polarized microspore stage. ADF7 was associated with the subapical actin fringe in germinating pollen grains.
      Title: Spatial and temporal expression of actin depolymerizing factors ADF7 and ADF10 during male gametophyte development in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_001341753.1
    NM_118691.3

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    acts_upstream_of_or_within actin filament depolymerization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin filament IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    actin depolymerizing factor 7
    NP_194289.2
    • actin depolymerizing factor 7 (ADF7); FUNCTIONS IN: actin binding; INVOLVED IN: biological_process unknown; LOCATED IN: intracellular; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, C globular stage, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Actin-binding, cofilin/tropomyosin type (InterPro:IPR002108); BEST Arabidopsis thaliana protein match is: actin depolymerizing factor 10 (TAIR:AT5G52360.1); Has 1500 Blast hits to 1497 proteins in 263 species: Archae - 0; Bacteria - 3; Metazoa - 654; Fungi - 151; Plants - 513; Viruses - 0; Other Eukaryotes - 179 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      13058936..13060250 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118691.3 → NP_194289.2  actin depolymerizing factor 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194289.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O65603, Q67ZM4, Q7FEI4
      UniProtKB/TrEMBL
      A0A5S9YD99, A0A654GAR4
      Conserved Domains (1) summary
      cd11286
      Location:6 → 136
      ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors

    2. NM_001341753.1 → NP_001329121.1  actin depolymerizing factor 7 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V4Q0, A0A1P8B6R9, A0A384L7F8, A0A5S9YD99, A0A654GAR4
      Conserved Domains (1) summary
      cl15697
      Location:1 → 129
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q67ZM4.1

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