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    GPRI1 GBF's pro-rich region-interacting factor 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816579, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GPRI1
    Official Full Name
    GBF's pro-rich region-interacting factor 1
    Primary source
    TAIR:AT2G20570
    Locus tag
    AT2G20570
    See related
    Araport:AT2G20570
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS GOLDEN2-LIKE 1; ATGLK1; GBF's pro-rich region-interacting factor 1; GLK1; GOLDEN2-LIKE 1; T13C7.1
    Summary
    Encodes GLK1, Golden2-like 1, one of a pair of partially redundant nuclear transcription factors that regulate chloroplast development in a cell-autonomous manner. GLK2, Golden2-like 2, is encoded by At5g44190. GLK1 and GLK2 regulate the expression of the photosynthetic apparatus.
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    Genomic context

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    See GPRI1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Sequence:
    Chromosome: 2; NC_003071.7 (8855302..8857758)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene DNAJ heat shock family protein Neighboring gene taximin Neighboring gene 26S proteasome regulatory subunit S2 1A Neighboring gene nuclear fusion defective 6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcription factor GLK1 promotes anthocyanin biosynthesis via an MBW complex-dependent pathway in Arabidopsis thaliana. Li Y, et al. J Integr Plant Biol, 2023 Jun. PMID 36856341
    2. The GLK1 'regulon' encodes disease defense related proteins and confers resistance to Fusarium graminearum in Arabidopsis. Savitch LV, et al. Biochem Biophys Res Commun, 2007 Jul 27. PMID 17533111
    3. Coordination of plastid protein import and nuclear gene expression by plastid-to-nucleus retrograde signaling. Kakizaki T, et al. Plant Physiol, 2009 Nov. PMID 19726569, Free PMC Article
    4. Arabidopsis GOLDEN2-LIKE (GLK) transcription factors activate jasmonic acid (JA)-dependent disease susceptibility to the biotrophic pathogen Hyaloperonospora arabidopsidis, as well as JA-independent plant immunity against the necrotrophic pathogen Botrytis cinerea. Murmu J, et al. Mol Plant Pathol, 2014 Feb. PMID 24393452, Free PMC Article
    5. Ubiquitin-Proteasome Dependent Regulation of the GOLDEN2-LIKE 1 Transcription Factor in Response to Plastid Signals. Tokumaru M, et al. Plant Physiol, 2017 Jan. PMID 27821720, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Natural genetic variation in GLK1-mediated photosynthetic acclimation in response to light.
      Title: Natural genetic variation in GLK1-mediated photosynthetic acclimation in response to light.
    2. Transcription factor GLK1 promotes anthocyanin biosynthesis via an MBW complex-dependent pathway in Arabidopsis thaliana.
      Title: Transcription factor GLK1 promotes anthocyanin biosynthesis via an MBW complex-dependent pathway in Arabidopsis thaliana.
    3. Shade represses photosynthetic genes by disrupting the DNA binding of GOLDEN2-LIKE1.
      Title: Shade represses photosynthetic genes by disrupting the DNA binding of GOLDEN2-LIKE1.
    4. Long-term abscisic acid promotes golden2-like1 degradation through constitutive photomorphogenic 1 in a light intensity-dependent manner to suppress chloroplast development.
      Title: Long-term abscisic acid promotes golden2-like1 degradation through constitutive photomorphogenic 1 in a light intensity-dependent manner to suppress chloroplast development.
    5. A BIN2-GLK1 Signaling Module Integrates Brassinosteroid and Light Signaling to Repress Chloroplast Development in the Dark.
      Title: A BIN2-GLK1 Signaling Module Integrates Brassinosteroid and Light Signaling to Repress Chloroplast Development in the Dark.
    6. The transcription factor AtGLK1 acts upstream of MYBL2 to genetically regulate sucrose-induced anthocyanin biosynthesis in Arabidopsis.
      Title: The transcription factor AtGLK1 acts upstream of MYBL2 to genetically regulate sucrose-induced anthocyanin biosynthesis in Arabidopsis.
    7. P69 binding to GLK proteins may interfere with the interaction between GLK proteins and upstream transcription factors, causing defective binding of GLK proteins to their targets.
      Title: Turnip Yellow Mosaic Virus P69 Interacts with and Suppresses GLK Transcription Factors to Cause Pale-Green Symptoms in Arabidopsis.
    8. silencing of AtRAP by AtlsiRNA-1 upon bacterial infection triggers defense responses through regulation of LSU2 and GLK1.
      Title: Silencing of AtRAP, a target gene of a bacteria-induced small RNA, triggers antibacterial defense responses through activation of LSU2 and down-regulation of GLK1.
    9. Plastid signals down-regulate the accumulation of GLK1 through the ubiquitin-proteasome pathway.
      Title: Ubiquitin-Proteasome Dependent Regulation of the GOLDEN2-LIKE 1 Transcription Factor in Response to Plastid Signals.
    10. Overexpressors of the Golden2-like transcription factors GLK1 and GLK2 were identified as genomes uncoupled mutants.
      Title: Definition of a core module for the nuclear retrograde response to altered organellar gene expression identifies GLK overexpressors as gun mutants.
    Submit: New GeneRIF Correction See all GeneRIFs (18)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001202633.1
    NM_001335694.1
    NM_127617.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within chloroplast organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of flower development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in negative regulation of leaf senescence IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of chlorophyll biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within signal transduction IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    GBF's pro-rich region-interacting factor 1
    NP_001189562.1
    • GBF's pro-rich region-interacting factor 1 (GPRI1); CONTAINS InterPro DOMAIN/s: Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), Myb-like DNA-binding domain, SHAQKYF class (InterPro:IPR006447), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: GOLDEN2-like 2 (TAIR:AT5G44190.1).
    NP_565476.1
    • GBF's pro-rich region-interacting factor 1 (GPRI1); CONTAINS InterPro DOMAIN/s: Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), Myb-like DNA-binding domain, SHAQKYF class (InterPro:IPR006447), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: GOLDEN2-like 2 (TAIR:AT5G44190.1); Has 2420 Blast hits to 2125 proteins in 147 species: Archae - 0; Bacteria - 17; Metazoa - 163; Fungi - 64; Plants - 2094; Viruses - 12; Other Eukaryotes - 70 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      8855302..8857758
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127617.3 → NP_565476.1  GBF's pro-rich region-interacting factor 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565476.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9C532, Q9SIV3
      UniProtKB/TrEMBL
      A0A178VXX4
      Conserved Domains (2) summary
      TIGR01557
      Location:153 → 208
      myb_SHAQKYF; myb-like DNA-binding domain, SHAQKYF class
      PLN03162
      Location:109 → 416
      PLN03162; golden-2 like transcription factor; Provisional

    2. NM_001202633.1 → NP_001189562.1  GBF's pro-rich region-interacting factor 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189562.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VXX4, F4IVF9
      Conserved Domains (2) summary
      TIGR01557
      Location:171 → 224
      myb_SHAQKYF; myb-like DNA-binding domain, SHAQKYF class
      PLN03162
      Location:109 → 432
      PLN03162; golden-2 like transcription factor; Provisional

    3. NM_001335694.1 → NP_001325394.1  GBF's pro-rich region-interacting factor 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VXX4, A0A1P8B320
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SIV3.2

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