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Links from Protein Clusters

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    ERF2 ethylene responsive element binding factor 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834768, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ERF2
    Official Full Name
    ethylene responsive element binding factor 2
    Primary source
    TAIR:AT5G47220
    Locus tag
    AT5G47220
    See related
    Araport:AT5G47220
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATERF-2; ATERF2; ETHYLENE RESPONSE FACTOR- 2; ethylene responsive element binding factor 2; ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 2; MQL5.7; MQL5_7
    Summary
    Encodes a member of the ERF (ethylene response factor) subfamily B-3 of ERF/AP2 transcription factor family (ATERF-2). The protein contains one AP2 domain. Functions as activator of GCC box#Aeidependent transcription. Positive regulator of JA-responsive defense genes and resistance to F. oxysporum and enhances JA inhibition of root elongation.
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    Genomic context

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    See ERF2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    1
    Sequence:
    Chromosome: 5; NC_003076.8 (19171643..19172956, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Ribosomal protein L19 family protein Neighboring gene RAB GTPase homolog 1A Neighboring gene Hyaluronan / mRNA binding family Neighboring gene pseudo Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ethylene plays an essential role in the recovery of Arabidopsis during post-anaerobiosis reoxygenation. Tsai KJ, et al. Plant Cell Environ, 2014 Oct. PMID 24506560
    2. Repressor- and activator-type ethylene response factors functioning in jasmonate signaling and disease resistance identified via a genome-wide screen of Arabidopsis transcription factor gene expression. McGrath KC, et al. Plant Physiol, 2005 Oct. PMID 16183832, Free PMC Article
    3. Arabidopsis ethylene-responsive element binding factors act as transcriptional activators or repressors of GCC box-mediated gene expression. Fujimoto SY, et al. Plant Cell, 2000 Mar. PMID 10715325, Free PMC Article
    4. Plant vascular cell division is maintained by an interaction between PXY and ethylene signalling. Etchells JP, et al. PLoS Genet, 2012. PMID 23166504, Free PMC Article
    5. The AP2/EREBP family of plant transcription factors. Riechmann JL, et al. Biol Chem, 1998 Jun. PMID 9687012

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Expression of several ethylene biosynthetic genes and ethylene-responsive factors, including ERF1 and ERF2, was induced during reoxygenation.
      Title: Ethylene plays an essential role in the recovery of Arabidopsis during post-anaerobiosis reoxygenation.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_124093.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell division IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within ethylene-activated signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within induced systemic resistance, jasmonic acid mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within phloem or xylem histogenesis IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in intracellular anatomical structure TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ethylene responsive element binding factor 2
    NP_199533.1
    • ethylene responsive element binding factor 2 (ERF2); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: ethylene responsive element binding factor 1 (TAIR:AT4G17500.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      19171643..19172956 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124093.3 → NP_199533.1  ethylene responsive element binding factor 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199533.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80338, Q682Y8, Q8LBU9
      UniProtKB/TrEMBL
      A0A178UCP3, A0A5S9YC34
      Conserved Domains (1) summary
      smart00380
      Location:116 → 180
      AP2; DNA-binding domain in plant proteins such as APETALA2 and EREBPs
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O80338.1

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