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    PAK6 p21 (RAC1) activated kinase 6 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 701589, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PAK6provided by VGNC
    Official Full Name
    p21 (RAC1) activated kinase 6provided by VGNC
    Primary source
    VGNC:VGNC:99207
    Locus tag
    EGK_17355
    See related
    Ensembl:ENSMMUG00000020534
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PAK6 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (16647502..16687158)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (16539690..16600828)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene Bcl2 modifying factor Neighboring gene BUB1 mitotic checkpoint serine/threonine kinase B Neighboring gene uncharacterized LOC114679380 Neighboring gene PAK6 antisense RNA 1 Neighboring gene ankyrin repeat domain 63 Neighboring gene phospholipase C beta 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase PAK 6
    Names
    p21(CDKN1A)-activated kinase 6
    NP_001248582.1
    XP_014997344.1
    XP_014997346.1
    XP_014997347.1
    XP_014997349.1
    XP_014997350.1
    XP_028706114.1
    XP_028706115.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261653.1 → NP_001248582.1  serine/threonine-protein kinase PAK 6

      See identical proteins and their annotated locations for NP_001248582.1

      Status: PROVISIONAL

      Source sequence(s)
      JV047705
      UniProtKB/TrEMBL
      A0A8J8Y883, F6TWF0, F7D8F1, G7MWM9
      Related
      ENSMMUP00000033842.1, ENSMMUT00000040817.3
      Conserved Domains (2) summary
      cd06659
      Location:385 → 681
      STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
      pfam00786
      Location:11 → 63
      PBD; P21-Rho-binding domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      16647502..16687158
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015141861.2 → XP_014997347.1  serine/threonine-protein kinase PAK 6 isoform X2

      UniProtKB/TrEMBL
      A0A8J8Y883, F6TWF0, F7D8F1, G7MWM9
      Related
      ENSMMUP00000027042.4, ENSMMUT00000028897.4
      Conserved Domains (2) summary
      cd06659
      Location:385 → 681
      STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
      pfam00786
      Location:11 → 63
      PBD; P21-Rho-binding domain

    2. XM_015141860.2 → XP_014997346.1  serine/threonine-protein kinase PAK 6 isoform X2

      UniProtKB/TrEMBL
      A0A8J8Y883, F6TWF0, F7D8F1, G7MWM9
      Conserved Domains (2) summary
      cd06659
      Location:385 → 681
      STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
      pfam00786
      Location:11 → 63
      PBD; P21-Rho-binding domain

    3. XM_015141863.1 → XP_014997349.1  serine/threonine-protein kinase PAK 6 isoform X2

      UniProtKB/TrEMBL
      A0A8J8Y883, F6TWF0, F7D8F1, G7MWM9
      Conserved Domains (2) summary
      cd06659
      Location:385 → 681
      STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
      pfam00786
      Location:11 → 63
      PBD; P21-Rho-binding domain

    4. XM_028850281.1 → XP_028706114.1  serine/threonine-protein kinase PAK 6 isoform X2

      UniProtKB/TrEMBL
      A0A8J8Y883, F6TWF0, F7D8F1, G7MWM9
      Conserved Domains (2) summary
      cd06659
      Location:385 → 681
      STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
      pfam00786
      Location:11 → 63
      PBD; P21-Rho-binding domain

    5. XM_028850282.1 → XP_028706115.1  serine/threonine-protein kinase PAK 6 isoform X2

      UniProtKB/TrEMBL
      A0A8J8Y883, F6TWF0, F7D8F1, G7MWM9
      Conserved Domains (2) summary
      cd06659
      Location:385 → 681
      STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
      pfam00786
      Location:11 → 63
      PBD; P21-Rho-binding domain

    6. XM_015141858.2 → XP_014997344.1  serine/threonine-protein kinase PAK 6 isoform X1

      Conserved Domains (3) summary
      smart00220
      Location:436 → 682
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd06659
      Location:409 → 705
      STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
      pfam00786
      Location:35 → 87
      PBD; P21-Rho-binding domain

    7. XM_015141864.2 → XP_014997350.1  serine/threonine-protein kinase PAK 6 isoform X2

      UniProtKB/TrEMBL
      A0A8J8Y883, F6TWF0, F7D8F1, G7MWM9
      Conserved Domains (2) summary
      cd06659
      Location:385 → 681
      STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
      pfam00786
      Location:11 → 63
      PBD; P21-Rho-binding domain
    Nucleotide Protein
    Heading Accession and Version

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