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    BUD5 Ras family guanine nucleotide exchange factor BUD5 [ Nakaseomyces glabratus ]

    Gene ID: 2886679, updated on 6-Dec-2024

    Summary

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    Gene symbol
    BUD5
    Gene description
    Ras family guanine nucleotide exchange factor BUD5
    Locus tag
    GVI51_B01133
    See related
    FungiDB:GVI51_B01133; VEuPathDB:GVI51_B01133
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Nakaseomyces glabratus (strain: ATCC 2001, nat-host: Homo sapiens, culture-collection: ATCC:2001, type-material: type material of Cryptococcus glabratus)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Nakaseomyces
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    Genomic context

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    See BUD5 in Genome Data Viewer
    Location:
    chromosome: B
    Exon count:
    1
    Sequence:
    Chromosome: B; NC_088952.1 (117842..121585)

    Chromosome B - NC_088952.1Genomic Context describing neighboring genes Neighboring gene EMG1 Neighboring gene transcriptional co-activator mating type protein alpha Neighboring gene MATalpha2 Neighboring gene tRNA-Thr Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_088952.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. De novo genome assembly of Candida glabrata reveals cell wall protein complement and structure of dispersed tandem repeat arrays. Xu Z, et al. Mol Microbiol, 2020 Jun. PMID 32068314
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    • CAGL0B01287g
      Has domain(s) with predicted guanyl-nucleotide exchange factor activity, role in regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction and intracellular localization

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Ras protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Ras family guanine nucleotide exchange factor BUD5
    XP_445026.1
    • CAGL0B01287g
      Has domain(s) with predicted guanyl-nucleotide exchange factor activity, role in regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction and intracellular localization

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_088952.1 Reference assembly

      Range
      117842..121585
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_445026.1 → XP_445026.1  Ras family guanine nucleotide exchange factor BUD5 [Nakaseomyces glabratus]

      See identical proteins and their annotated locations for XP_445026.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A0W0DXB2, Q6FXB3
      Conserved Domains (3) summary
      cd06224
      Location:688 → 821
      REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
      pfam00617
      Location:968 → 1163
      RasGEF; RasGEF domain
      cl17036
      Location:152 → 210
      SH3; Src Homology 3 domain superfamily
    Nucleotide Protein
    Heading Accession and Version

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