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    Mb21d2 Mab-21 domain containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 239796, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mb21d2provided by MGI
    Official Full Name
    Mab-21 domain containing 2provided by MGI
    Primary source
    MGI:MGI:1917028
    See related
    Ensembl:ENSMUSG00000051065 AllianceGenome:MGI:1917028
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A430031N04; 1600021P15Rik
    Summary
    Predicted to enable nucleotidyltransferase activity. Orthologous to human MB21D2 (Mab-21 domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 10.6), whole brain E14.5 (RPKM 9.5) and 27 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Mb21d2 in Genome Data Viewer
    Location:
    16 B2; 16 19.71 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (28644928..28748802, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (28826176..28929712, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene fibroblast growth factor 12 Neighboring gene predicted gene, 46548 Neighboring gene STARR-seq mESC enhancer starr_40512 Neighboring gene STARR-seq mESC enhancer starr_40513 Neighboring gene STARR-seq mESC enhancer starr_40515 Neighboring gene STARR-seq mESC enhancer starr_40516 Neighboring gene predicted gene, 20018 Neighboring gene STARR-seq mESC enhancer starr_40518 Neighboring gene STARR-seq mESC enhancer starr_40520 Neighboring gene predicted gene 8253 Neighboring gene STARR-seq mESC enhancer starr_40521 Neighboring gene phospholipase A and acyltransferase 1 Neighboring gene ATPase type 13A5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression. Ahmed SM, et al. J Cell Biol, 2012 Dec 10. PMID 23209302, Free PMC Article
    2. The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis. Menon S, et al. Mol Biol Cell, 2021 Feb 15. PMID 33378226, Free PMC Article
    3. Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Munton RP, et al. Mol Cell Proteomics, 2007 Feb. PMID 17114649
    4. The central role of EED in the orchestration of polycomb group complexes. Cao Q, et al. Nat Commun, 2014. PMID 24457600, Free PMC Article
    5. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (5) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC103296

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables nucleotidyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nucleotidyltransferase MB21D2
    Names
    mab-21 domain-containing protein 2
    protein MB21D2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001405899.1 → NP_001392828.1  nucleotidyltransferase MB21D2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC154807
      UniProtKB/Swiss-Prot
      Q5U4H4, Q8C525

    2. NM_001405900.1 → NP_001392829.1  nucleotidyltransferase MB21D2 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC154807
      UniProtKB/Swiss-Prot
      Q5U4H4, Q8C525

    3. NM_177718.4 → NP_808386.2  nucleotidyltransferase MB21D2 isoform 1

      See identical proteins and their annotated locations for NP_808386.2

      Status: VALIDATED

      Source sequence(s)
      AC154807
      Consensus CDS
      CCDS28093.1
      UniProtKB/Swiss-Prot
      Q5U4H4, Q8C525
      UniProtKB/TrEMBL
      D3Z742
      Related
      ENSMUSP00000097600.2, ENSMUST00000100023.3
      Conserved Domains (1) summary
      pfam03281
      Location:176 → 401
      Mab-21; Mab-21 protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      28644928..28748802 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006522117.1 → XP_006522180.1  nucleotidyltransferase MB21D2 isoform X3

      UniProtKB/Swiss-Prot
      Q5U4H4, Q8C525
      Conserved Domains (1) summary
      pfam03281
      Location:117 → 342
      Mab-21; Mab-21 protein
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8C525.1 GenPept UniProtKB/Swiss-Prot:Q8C525

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