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    znf-236 C2H2-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 3565634, updated on 9-Dec-2024

    Summary

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    Official Symbol
    znf-236
    Official Full Name
    C2H2-type domain-containing protein
    Primary source
    WormBase:WBGene00021689
    Locus tag
    CELE_Y48G8AL.10
    See related
    AllianceGenome:WB:WBGene00021689
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including ZNF208 (zinc finger protein 208); ZNF729 (zinc finger protein 729); and ZNF845 (zinc finger protein 845). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See znf-236 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    13
    Sequence:
    Chromosome: I; NC_003279.8 (1136366..1154388, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Homeobox domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene AP complex mu/sigma subunit domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Caenorhabditis elegans fibroblast growth factor receptor signaling can occur independently of the multi-substrate adaptor FRS2. Lo TW, et al. Genetics, 2010 Jun. PMID 20308281, Free PMC Article
    2. Identification and characterization of novel nicotinic receptor-associated proteins in Caenorhabditis elegans. Gottschalk A, et al. EMBO J, 2005 Jul 20. PMID 15990870, Free PMC Article
    3. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    C2H2-type domain-containing protein
    NP_001293225.1
    • Confirmed by transcript evidence
    NP_001293226.1
    • Confirmed by transcript evidence
    NP_001293227.1
    • Confirmed by transcript evidence
    NP_001293228.1
    • Confirmed by transcript evidence
    NP_001293229.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      1136366..1154388 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001306296.3 → NP_001293225.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293225.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      V6CKC3
      Conserved Domains (3) summary
      sd00017
      Location:854 → 874
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:515 → 536
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:924 → 948
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001306297.3 → NP_001293226.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293226.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      V6CLQ3
      Conserved Domains (3) summary
      sd00017
      Location:491 → 511
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:152 → 173
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:561 → 585
      zf-H2C2_2; Zinc-finger double domain

    3. NM_001306298.3 → NP_001293227.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293227.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      V6CLP6
      Conserved Domains (3) summary
      sd00017
      Location:479 → 499
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:140 → 161
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:549 → 573
      zf-H2C2_2; Zinc-finger double domain

    4. NM_001306299.3 → NP_001293228.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293228.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      V6CLK2
      Conserved Domains (3) summary
      sd00017
      Location:179 → 199
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:234 → 256
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:249 → 273
      zf-H2C2_2; Zinc-finger double domain

    5. NM_001306300.3 → NP_001293229.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293229.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      V6CJ81
    Nucleotide Protein
    Heading Accession and Version

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