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    FASLG Fas ligand [ Cercocebus atys (sooty mangabey) ]

    Gene ID: 105597557, updated on 13-Mar-2024

    Summary

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    Gene symbol
    FASLG
    Gene description
    Fas ligand
    See related
    Ensembl:ENSCATG00000034389
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Cercocebus atys
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
    Also known as
    FASL; CD95L; CD95-L; TNFSF6
    Orthologs
    human mouse all
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    Genomic context

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    See FASLG in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012002093.1 (1069035..1077048)

    NW_012002093.1Genomic Context describing neighboring genes Neighboring gene zinc finger homeobox protein 4-like Neighboring gene uncharacterized LOC105597554 Neighboring gene SUN domain containing ossification factor Neighboring gene uncharacterized LOC105597558 Neighboring gene TNF superfamily member 18

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_012002093.1 Unplaced Scaffold Reference Caty_1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning, sequencing, and homology analysis of nonhuman primate Fas/Fas-ligand and co-stimulatory molecules. Villinger F, et al. Immunogenetics, 2001 May-Jun. PMID 11491535
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables tumor necrosis factor receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in extrinsic apoptotic signaling pathway via death domain receptors IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tumor necrosis factor ligand superfamily member 6
    Names
    CD95 ligand
    Fas antigen ligand

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001305960.1 → NP_001292889.1  tumor necrosis factor ligand superfamily member 6

      See identical proteins and their annotated locations for NP_001292889.1

      Status: PROVISIONAL

      Source sequence(s)
      AF344847
      UniProtKB/Swiss-Prot
      Q9BDN1
      Conserved Domains (1) summary
      cd00184
      Location:145 → 278
      TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...

    RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Caty_1.0

    Genomic

    1. NW_012002093.1 Reference Caty_1.0

      Range
      1069035..1077048
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012085910.1 → XP_011941300.1  tumor necrosis factor ligand superfamily member 6

      Related
      ENSCATP00000021314.1, ENSCATT00000045516.1
      Conserved Domains (1) summary
      cd00184
      Location:145 → 278
      TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9BDN1.1 GenPept UniProtKB/Swiss-Prot:Q9BDN1

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