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    TRAF6 TNF receptor associated factor 6 [ Cercocebus atys (sooty mangabey) ]

    Gene ID: 105586809, updated on 13-Mar-2024

    Summary

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    Gene symbol
    TRAF6
    Gene description
    TNF receptor associated factor 6
    See related
    Ensembl:ENSCATG00000030633
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Cercocebus atys
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
    Orthologs
    human mouse all
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    Genomic context

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    See TRAF6 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012010243.1 (8501821..8524375, complement)

    NW_012010243.1Genomic Context describing neighboring genes Neighboring gene COMM domain containing 9 Neighboring gene proline rich 5 like Neighboring gene recombination activating 1 Neighboring gene intraflagellar transport associated protein Neighboring gene recombination activating 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_012010243.1 Unplaced Scaffold Reference Caty_1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections. Mandl JN, et al. Nat Med, 2008 Oct. PMID 18806803
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables tumor necrosis factor receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in interleukin-1-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of JNK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of NF-kappaB transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein K63-linked ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tumor necrosis factor-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of plasma membrane signaling receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    TNF receptor-associated factor 6
    Names
    E3 ubiquitin-protein ligase TRAF6
    RING-type E3 ubiquitin transferase TRAF6
    XP_011917665.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001305961.1 → NP_001292890.1  TNF receptor-associated factor 6

      See identical proteins and their annotated locations for NP_001292890.1

      Status: PROVISIONAL

      Source sequence(s)
      EU204928
      UniProtKB/Swiss-Prot
      B6CJY4
      Conserved Domains (5) summary
      PRK04778
      Location:287 → 348
      PRK04778; septation ring formation regulator EzrA; Provisional
      cd03776
      Location:351 → 500
      MATH_TRAF6; Tumor Necrosis Factor Receptor (TNFR)-Associated Factor (TRAF) family, TRAF6 subfamily, TRAF domain, C-terminal MATH subdomain; composed of proteins with similarity to human TRAF6, including the Drosophila protein DTRAF2. TRAF molecules serve as adapter ...
      pfam02176
      Location:204 → 261
      zf-TRAF; TRAF-type zinc finger
      pfam18048
      Location:157 → 183
      TRAF6_Z2; TNF receptor-associated factor 6 zinc finger 2
      cd16643
      Location:67 → 124
      mRING-HC-C3HC3D_TRAF6; Modified RING finger, HC subclass (C3HC3D-type), found in tumor necrosis factor (TNF) receptor-associated factor 6 (TRAF6) and similar proteins

    RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Caty_1.0

    Genomic

    1. NW_012010243.1 Reference Caty_1.0

      Range
      8501821..8524375 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012062275.1 → XP_011917665.1  TNF receptor-associated factor 6

      Related
      ENSCATP00000012971.1, ENSCATT00000037104.1
      Conserved Domains (5) summary
      PRK04778
      Location:287 → 348
      PRK04778; septation ring formation regulator EzrA; Provisional
      cd03776
      Location:351 → 500
      MATH_TRAF6; Tumor Necrosis Factor Receptor (TNFR)-Associated Factor (TRAF) family, TRAF6 subfamily, TRAF domain, C-terminal MATH subdomain; composed of proteins with similarity to human TRAF6, including the Drosophila protein DTRAF2. TRAF molecules serve as adapter ...
      pfam02176
      Location:204 → 261
      zf-TRAF; TRAF-type zinc finger
      pfam18048
      Location:157 → 183
      TRAF6_Z2; TNF receptor-associated factor 6 zinc finger 2
      cd16643
      Location:67 → 124
      mRING-HC-C3HC3D_TRAF6; Modified RING finger, HC subclass (C3HC3D-type), found in tumor necrosis factor (TNF) receptor-associated factor 6 (TRAF6) and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B6CJY4.1 GenPept UniProtKB/Swiss-Prot:B6CJY4

    Gene LinkOut

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