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    TET8 tetraspanin8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816913, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TET8
    Official Full Name
    tetraspanin8
    Primary source
    TAIR:AT2G23810
    Locus tag
    AT2G23810
    See related
    Araport:AT2G23810
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F27L4.1; F27L4_1; tetraspanin8
    Summary
    Member of TETRASPANIN family
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    Genomic context

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    See TET8 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    2
    Sequence:
    Chromosome: 2; NC_003071.7 (10135605..10137595, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene geranylgeranyl pyrophosphate synthase 2 Neighboring gene miscRNA Neighboring gene Metal-dependent phosphohydrolase Neighboring gene PapD-like superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis TETRASPANIN8 mediates exosome secretion and glycosyl inositol phosphoceramide sorting and trafficking. Liu N, et al. Plant Cell, 2024 Feb 26. PMID 37950906, Free PMC Article
    2. Functional Analysis of the Arabidopsis TETRASPANIN Gene Family in Plant Growth and Development. Wang F, et al. Plant Physiol, 2015 Nov. PMID 26417009, Free PMC Article
    3. Arabidopsis Tetraspanins Facilitate Virus Infection via Membrane-Recognition GCCK/RP Motif and Cysteine Residues. Zhu T, et al. Front Plant Sci, 2022. PMID 35310653, Free PMC Article
    4. Identification of new intrinsic proteins in Arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2004 Jul. PMID 15060130
    5. Mapping the Arabidopsis organelle proteome. Dunkley TP, et al. Proc Natl Acad Sci U S A, 2006 Apr 25. PMID 16618929, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_179714.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables sphingolipid binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in COPII-coated vesicle cargo loading IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    involved_in auxin-activated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within defense response to Gram-negative bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    involved_in sphingolipid translocation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in extracellular exosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasmodesma HDA PubMed 
    located_in vacuole HDA PubMed 

    General protein information

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    Preferred Names
    tetraspanin8
    NP_850045.2
    • tetraspanin8 (TET8); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: aging; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Tetraspanin (InterPro:IPR018499), Tetraspanin, conserved site (InterPro:IPR018503), Tetraspanin, subgroup (InterPro:IPR000301); BEST Arabidopsis thaliana protein match is: tetraspanin9 (TAIR:AT4G30430.1); Has 603 Blast hits to 600 proteins in 63 species: Archae - 0; Bacteria - 0; Metazoa - 159; Fungi - 0; Plants - 433; Viruses - 0; Other Eukaryotes - 11 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      10135605..10137595 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_179714.5 → NP_850045.2  tetraspanin8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850045.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O64822, Q683G1, Q8S8N8, Q8S8Q6
      UniProtKB/TrEMBL
      A0A178VYI5, A0A5S9X0Q4, A0A7G2EEI0
      Conserved Domains (1) summary
      pfam00335
      Location:5 → 254
      Tetraspannin; Tetraspanin family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8S8Q6.1

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