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    KPNA1 karyopherin subunit alpha 1 [ Cercocebus atys (sooty mangabey) ]

    Gene ID: 105589776, updated on 13-Mar-2024

    Summary

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    Gene symbol
    KPNA1
    Gene description
    karyopherin subunit alpha 1
    See related
    Ensembl:ENSCATG00000039950
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cercocebus atys
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
    Orthologs
    human mouse all
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    Genomic context

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    See KPNA1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012001053.1 (5321544..5411408, complement)

    NW_012001053.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105589774 Neighboring gene family with sequence similarity 162 member A Neighboring gene WD repeat domain 5B Neighboring gene poly(ADP-ribose) polymerase family member 9 Neighboring gene poly [ADP-ribose] polymerase 15-like Neighboring gene deltex E3 ubiquitin ligase 3L

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_012001053.1 Unplaced Scaffold Reference Caty_1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables nuclear import signal receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear localization sequence binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in NLS-bearing protein import into nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in postsynapse to nucleus signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    importin subunit alpha-5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Caty_1.0

    Genomic

    1. NW_012001053.1 Reference Caty_1.0

      Range
      5321544..5411408 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012068535.1 → XP_011923925.1  importin subunit alpha-5 isoform X2

      See identical proteins and their annotated locations for XP_011923925.1

      UniProtKB/TrEMBL
      A0A2K5N988
      Related
      ENSCATP00000034024.1, ENSCATT00000058300.1
      Conserved Domains (3) summary
      COG5064
      Location:33 → 516
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      sd00044
      Location:88 → 116
      HEAT; HEAT repeat [structural motif]
      sd00043
      Location:128 → 154
      ARM; armadillo repeat [structural motif]

    2. XM_012068534.1 → XP_011923924.1  importin subunit alpha-5 isoform X1

      Conserved Domains (2) summary
      COG5064
      Location:25 → 455
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      sd00043
      Location:67 → 93
      ARM; armadillo repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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