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    ORC1 origin recognition complex subunit 1 [ Mandrillus leucophaeus (drill) ]

    Gene ID: 105534860, updated on 13-Mar-2024

    Summary

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    Gene symbol
    ORC1
    Gene description
    origin recognition complex subunit 1
    See related
    Ensembl:ENSMLEG00000038870
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Mandrillus leucophaeus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Mandrillus
    Orthologs
    human mouse all
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    Genomic context

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    See ORC1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    100 current Mleu.le_1.0 (GCF_000951045.1) Unplaced Scaffold NW_012101365.1 (1817503..1859047, complement)

    NW_012101365.1Genomic Context describing neighboring genes Neighboring gene zinc finger FYVE-type containing 9 Neighboring gene anaphase-promoting complex subunit 10 pseudogene Neighboring gene coiled-coil and C2 domain containing 1B Neighboring gene pre-mRNA processing factor 38A Neighboring gene terminal uridylyl transferase 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_012101365.1 Unplaced Scaffold Reference Mleu.le_1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA replication origin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables chromatin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA replication initiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitotic DNA replication checkpoint signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of nuclear origin of replication recognition complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    origin recognition complex subunit 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Mandrillus leucophaeus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mleu.le_1.0

    Genomic

    1. NW_012101365.1 Reference Mleu.le_1.0

      Range
      1817503..1859047 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011973766.1 → XP_011829156.1  origin recognition complex subunit 1

      See identical proteins and their annotated locations for XP_011829156.1

      UniProtKB/TrEMBL
      A0A2K5ZNC6, A0A2K5ZNH6
      Related
      ENSMLEP00000029330.1, ENSMLET00000052886.1
      Conserved Domains (5) summary
      cd04719
      Location:44 → 170
      BAH_Orc1p_animal; BAH, or Bromo Adjacent Homology domain, as present in animal homologs of Saccharomyces cerevisiae Orc1p. Orc1 is part of the Yeast Sir1-origin recognition complex. The Orc1p BAH doman functions in epigenetic silencing. In vertebrates, a similar ORC ...
      TIGR02928
      Location:494 → 826
      TIGR02928; orc1/cdc6 family replication initiation protein
      pfam09079
      Location:777 → 850
      Cdc6_C; CDC6, C terminal
      pfam13191
      Location:503 → 553
      AAA_16; AAA ATPase domain
      cl21455
      Location:529 → 674
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    2. XM_011973765.1 → XP_011829155.1  origin recognition complex subunit 1

      See identical proteins and their annotated locations for XP_011829155.1

      UniProtKB/TrEMBL
      A0A2K5ZNC6, A0A2K5ZNH6
      Related
      ENSMLEP00000029326.1, ENSMLET00000052882.1
      Conserved Domains (5) summary
      cd04719
      Location:44 → 170
      BAH_Orc1p_animal; BAH, or Bromo Adjacent Homology domain, as present in animal homologs of Saccharomyces cerevisiae Orc1p. Orc1 is part of the Yeast Sir1-origin recognition complex. The Orc1p BAH doman functions in epigenetic silencing. In vertebrates, a similar ORC ...
      TIGR02928
      Location:494 → 826
      TIGR02928; orc1/cdc6 family replication initiation protein
      pfam09079
      Location:777 → 850
      Cdc6_C; CDC6, C terminal
      pfam13191
      Location:503 → 553
      AAA_16; AAA ATPase domain
      cl21455
      Location:529 → 674
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein
    Heading Accession and Version

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