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    GRB2 growth factor receptor bound protein 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 535298, updated on 4-Oct-2024

    Summary

    Official Symbol
    GRB2provided by VGNC
    Official Full Name
    growth factor receptor bound protein 2provided by VGNC
    Primary source
    VGNC:VGNC:29631
    See related
    BGD:BT17792; Ensembl:ENSBTAG00000004736
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    NEW
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    Genomic context

    See GRB2 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (56117213..56183327)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene CASK interacting protein 2 Neighboring gene transmembrane protein 94 Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene solute carrier family 25 member 19 Neighboring gene MIF4G domain containing Neighboring gene mitochondrial ribosomal protein S7

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Pathways from PubChem

    General protein information

    Preferred Names
    growth factor receptor-bound protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034630.1NP_001029802.1  growth factor receptor-bound protein 2

      See identical proteins and their annotated locations for NP_001029802.1

      Status: PROVISIONAL

      Source sequence(s)
      BC102411
      UniProtKB/TrEMBL
      A0AAA9TWK5, Q3T0F9
      Related
      ENSBTAP00000006216.5, ENSBTAT00000006216.6
      Conserved Domains (3) summary
      cd09941
      Location:56150
      SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
      cd11946
      Location:156
      SH3_GRB2_N; N-terminal Src homology 3 domain of Growth factor receptor-bound protein 2
      cd11949
      Location:160212
      SH3_GRB2_C; C-terminal Src homology 3 domain of Growth factor receptor-bound protein 2

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      56117213..56183327
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010816566.3XP_010814868.1  growth factor receptor-bound protein 2 isoform X1

      See identical proteins and their annotated locations for XP_010814868.1

      UniProtKB/TrEMBL
      A0AAA9TWK5, Q3T0F9
      Conserved Domains (3) summary
      cd09941
      Location:56150
      SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
      cd11946
      Location:156
      SH3_GRB2_N; N-terminal Src homology 3 domain of Growth factor receptor-bound protein 2
      cd11949
      Location:160212
      SH3_GRB2_C; C-terminal Src homology 3 domain of Growth factor receptor-bound protein 2
    2. XM_024980286.1XP_024836054.1  growth factor receptor-bound protein 2 isoform X2

      UniProtKB/TrEMBL
      A0AAA9SNB1
      Related
      ENSBTAP00000084332.1, ENSBTAT00000128468.1
      Conserved Domains (3) summary
      cd09941
      Location:39133
      SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
      cd11949
      Location:143195
      SH3_GRB2_C; C-terminal Src homology 3 domain of Growth factor receptor-bound protein 2
      cl17036
      Location:939
      SH3; Src Homology 3 domain superfamily