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    Sec22a SEC22 homolog A, vesicle trafficking protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 117513, updated on 9-Dec-2024

    Summary

    Official Symbol
    Sec22aprovided by RGD
    Official Full Name
    SEC22 homolog A, vesicle trafficking proteinprovided by RGD
    Primary source
    RGD:621659
    See related
    EnsemblRapid:ENSRNOG00000043069 AllianceGenome:RGD:621659
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Sec22l2
    Summary
    Involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in endoplasmic reticulum membrane. Orthologous to human SEC22A (SEC22 homolog A, vesicle trafficking protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 123.3), Liver (RPKM 79.8) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Sec22a in Genome Data Viewer
    Location:
    11q22
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (78907552..78967575)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (65402583..65462329)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (68633080..68686553)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene protein disulfide isomerase family A, member 5 Neighboring gene uncharacterized LOC120095661 Neighboring gene uncharacterized LOC120095660 Neighboring gene uncharacterized LOC102551038 Neighboring gene adenylate cyclase 5 Neighboring gene uncharacterized LOC134481009

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    vesicle-trafficking protein SEC22a
    Names
    SEC22 vesicle trafficking protein homolog A
    SEC22 vesicle-trafficking protein-like 2
    rSec22a

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_057147.2NP_476488.2  vesicle-trafficking protein SEC22a

      See identical proteins and their annotated locations for NP_476488.2

      Status: PROVISIONAL

      Source sequence(s)
      BC081746
      UniProtKB/Swiss-Prot
      Q62891, Q642F4
      UniProtKB/TrEMBL
      A0A8I6G2P2, A6IRG9
      Related
      ENSRNOP00000061258.2, ENSRNOT00000063795.4
      Conserved Domains (1) summary
      cd14824
      Location:5126
      Longin; longin domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      78907552..78967575
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008768693.4XP_008766915.3  vesicle-trafficking protein SEC22a isoform X1

      Related
      ENSRNOP00000104395.1, ENSRNOT00000166378.1
    2. XM_039087918.2XP_038943846.1  vesicle-trafficking protein SEC22a isoform X2

      Conserved Domains (1) summary
      cd14824
      Location:156
      Longin; longin domain