U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    TEK TEK receptor tyrosine kinase [ Pteropus vampyrus (large flying fox) ]

    Gene ID: 105308731, updated on 11-Apr-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    TEK
    Gene description
    TEK receptor tyrosine kinase
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pteropus vampyrus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Pteropodinae; Pteropus
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See TEK in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    101 current Pvam_2.0 (GCF_000151845.1) Unplaced Scaffold NW_011889400.1 (451915..553069, complement)

    NW_011889400.1Genomic Context describing neighboring genes Neighboring gene MOB kinase activator 3B Neighboring gene 5S ribosomal RNA Neighboring gene equatorin Neighboring gene 5S ribosomal RNA Neighboring gene intraflagellar transport 74 Neighboring gene leucine rich repeat containing 19

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NW_011889400 Unplaced Scaffold Reference Pvam_2.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane receptor protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in angiogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in endothelial cell proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of endothelial cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    angiopoietin-1 receptor

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Pteropus vampyrus Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Pvam_2.0

    Genomic

    1. NW_011889400.1 Reference Pvam_2.0

      Range
      451915..553069 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011384728.1 → XP_011383030.1  angiopoietin-1 receptor isoform X3

      UniProtKB/TrEMBL
      A0A6P3S0G4
      Conserved Domains (5) summary
      cd05088
      Location:669 → 971
      PTKc_Tie2; Catalytic domain of the Protein Tyrosine Kinase, Tie2
      smart00221
      Location:677 → 945
      STYKc; Protein kinase; unclassified specificity
      cd00055
      Location:126 → 171
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00063
      Location:493 → 585
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:397 → 480
      fn3; Fibronectin type III domain

    2. XM_011384727.1 → XP_011383029.1  angiopoietin-1 receptor isoform X2

      UniProtKB/TrEMBL
      A0A6P3RN22
      Conserved Domains (6) summary
      cd05088
      Location:774 → 1076
      PTKc_Tie2; Catalytic domain of the Protein Tyrosine Kinase, Tie2
      smart00221
      Location:782 → 1050
      STYKc; Protein kinase; unclassified specificity
      cd00055
      Location:230 → 275
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00063
      Location:597 → 689
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:501 → 584
      fn3; Fibronectin type III domain
      pfam10430
      Location:24 → 118
      Ig_Tie2_1; Tie-2 Ig-like domain 1

    3. XM_011384726.1 → XP_011383028.1  angiopoietin-1 receptor isoform X1

      UniProtKB/TrEMBL
      A0A6P3RKJ4
      Conserved Domains (6) summary
      cd05088
      Location:817 → 1119
      PTKc_Tie2; Catalytic domain of the Protein Tyrosine Kinase, Tie2
      smart00221
      Location:825 → 1093
      STYKc; Protein kinase; unclassified specificity
      cd00055
      Location:230 → 275
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00063
      Location:640 → 732
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:544 → 627
      fn3; Fibronectin type III domain
      pfam10430
      Location:24 → 118
      Ig_Tie2_1; Tie-2 Ig-like domain 1
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.