bsk146 brain specific kinase 146 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: bsk146provided by ZNC
Official Full Name: brain specific kinase 146provided by ZNC
Primary source: ZFIN:ZDB-GENE-060313-3
See related: Ensembl:ENSDARG00000099069 AllianceGenome:ZFIN:ZDB-GENE-060313-3
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: sbk1
Summary: Enables protein kinase activity. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in cytoplasm. Is expressed in brain; eye; and immature eye. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 12

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (546279..558201, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (542336..552471, complement)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

BSK146 is a brain-specific protein kinase zebrafish
Title: Expression and characterization of a brain-specific protein kinase BSK146 from zebrafish.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables protein kinase activity	IDA Inferred from Direct Assay more info	PubMed
enables protein kinase activity	IEA Inferred from Electronic Annotation more info
enables protein serine kinase activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein phosphorylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: serine/threonine-protein kinase SBK1

Names: SH3 domain-binding kinase 1; SH3-binding kinase 1; brain-specific protein kinase BSK146; protein kinase Bsk146

NP_998006.2

EC 2.7.11.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_212841.2 → NP_998006.2 serine/threonine-protein kinase SBK1

Status: VALIDATED

Source sequence(s)

BX000348

UniProtKB/Swiss-Prot

Q90ZY4

UniProtKB/TrEMBL

A0A8M3B753, B3DGG2

Related

ENSDARP00000134385.1, ENSDART00000158355.2

Conserved Domains (1) summary

cd13987
Location:38 → 296

STKc_SBK1; Catalytic domain of the Serine/Threonine kinase, SH3 Binding Kinase 1